Zobrazeno 1 - 10
of 113
pro vyhledávání: '"D.E. Duggan"'
Autor:
D.E. Duggan, Jane K. Setlow
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects. 87:664-668
Micrococcus radiodurans seems to have a very efficient DNA repair mechanism. The organism is very resistant to ultraviolet radiation, although the DNA is not exceptionally resistant to ultraviolet damage, as indicated by thymine dimerization.
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects. 68:519-525
6-Methylaminopurine-free base is efficiently utilized by growing cultures of various mutants of Salmonella typhimurium for the biosynthesis of polynucleotide purines. In the “purineless” mutant Ade-11 it competes favorably with adenine, guanine a
Autor:
D.E. Duggan, R.M. Noll
Publikováno v:
Archives of Biochemistry and Biophysics. 109:388-396
Adenosinetriphosphatase systems have been isolated from renal cortex of several species. In guinea pig preparation, the “membrane ATPase,” or Na + -K + -Mg ++ -dependent and ouabain-sensitive component comprises 80–85% of total activity, and is
Autor:
D.E. Duggan, E. Titus
Publikováno v:
Biochimica et Biophysica Acta. 55:273-275
Autor:
D.E. Duggan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects. 68:319-321
Publikováno v:
Analytical biochemistry. 77(1)
Studies have been carried out to develop a gas-liquid chromatographic-mass spectrometric assay for determining the uric acid body pool size in animals. A known quantity of [1,3-15N]uric acid is administered and the uric acid fraction is isolated from
Publikováno v:
Clinical pharmacology and therapeutics. 33(2)
Four subjects were studied by continuous intraduodenal sampling to establish the existence and determine the extent of enterohepatic recirculation of sulindac and its sulfide and sulfone metabolites. Sulindac, 200 mg by mouth, was given every 12 hr f
Publikováno v:
Clinical pharmacology and therapeutics. 21(3)
The disposition of sulindac, a new nonsteroid anti-inflammatory drug, has been studied in normal volunteers in five separate clinical studies. Based upon material balance considerations, a minimum of approximately 88% of an oral dose is absorbed. The
Publikováno v:
Analytical biochemistry. 94(2)
An isotope dilution procedure for oxalate based upon [1,2- 13 C 2 ]oxalic acid is described. For routine determinations of urinary concentration, a known quantity of sodium [1,2- 13 C]oxalate is admixed with the sample, total oxalate precipitated as
Publikováno v:
Analytical biochemistry. 94(2)
An analytical procedure for the estimation of urinary oxalate is described which satisfies the requirements of specificity, recovery, and negligible generation of oxalate from progenitors. The procedure involves precipitation of oxalate from urine as