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Publikováno v:
Transl Res
Post-thrombotic syndrome (PTS) is an end stage manifestation of deep vein thrombosis. This is an inherently inflammatory process, with consequent fibrosis. Multiple cellular types are involved, and are likely driven by leukocytes. Herein, we review t
Akademický článek
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Autor:
Cathy Luke, Joe F. Baldwin, D.D. Myers, Peter K. Henke, Jose A. Diaz, Megan Elfline, Vikram Sood, Thomas W. Wakefield, Nicholas A. Dewyer
Publikováno v:
Journal of Vascular Surgery. 56(4):1089-1097
ObjectiveDeep vein thrombosis (DVT) resolution instigates an inflammatory response, resulting in vessel wall damage and scarring. Urokinase-plasminogen activator (uPA) and its inhibitor, plasminogen activator inhibitor-1 (PAI-1), are integral compone
Autor:
D.D. Myers, Erin M. Miller, Mayo Mitsuya, Thomas W. Wakefield, Cathy Luke, Peter K. Henke, Vikram Sood, Gilbert R. Upchurch
Publikováno v:
Annals of Vascular Surgery. 24:233-241
Venous thrombus resolution sets up an early intense inflammatory reaction, from which vein wall damage results. Tissue response to injury includes matrix metalloproteinase (MMP) activation and extracellular matrix protein turnover. This study sought
Autor:
D.D. Myers, Erin M. Miller, Cathy Luke, Mayo Mitsuya, Vikram Sood, Peter K. Henke, Thomas W. Wakefield, Gilbert R. Upchurch
Publikováno v:
Annales de Chirurgie Vasculaire. 24:256-265
La resolution du thrombus veineux est a la source d’une reaction inflammatoire intense precoce, provoquant les lesions de la paroi veineuse. La reponse des tissus aux lesions inclut l’activation de metalloproteinases de la matrice (MMP) et la reg
Autor:
D.D. Myers, Joseph D. Raffetto, Kathleen J. Ozsvath, Brajesh K. Lal, Jose A. Diaz, Faisal Aziz
Publikováno v:
Journal of Vascular Surgery: Venous and Lymphatic Disorders. 4:148-149
Autor:
M.M. Gokhale, D.D. Myers
Publikováno v:
2007 IEEE International Engineering Management Conference.
Roadmaps serve as a useful graphical tool to integrate strategic objectives, technology-assessment, technology-roadmapping and product road mapping against an axis of time. Much research has been done related to linking specific technologies with the
Autor:
Matthew O'Donnell, Salavat R. Aglyamov, D.D. Myers, Hua Xie, Jonathan M. Rubin, Kang Kim, Stanislav Emelianov, Thomas W. Wakefield
Publikováno v:
Medical Imaging 2004: Ultrasonic Imaging and Signal Processing.
Recently, it was suggested that ultrasound elasticity imaging can be used to age deep vein thrombosis (DVT) since blood clot hardness changes with fibrin content. The main components of ultrasound elasticity imaging are deformation of the object, spe
Autor:
Thomas W. Wakefield, Angela E. Hawley, Vita V. Sullivan, Matthew J. Eagleton, Shirley K. Wrobleski, Andrea Varga, Diana M. Farris, J. B. Fowlkes, D.D. Myers, P Thanapron, Brian S. Knipp
Publikováno v:
The Journal of surgical research. 109(1)
The purpose of this study was to quantify the fibrin content of thrombi produced in a mouse model of venous thrombosis and correlate this to thrombus mass. The role of P-selectin, E-selectin, and IL-10 on thrombus fibrin content was analyzed using kn