Real-time quantification of osteoclastic resorptive activity by electric cell-substrate impedance sensing

Autor: Ineke D.C. Jansen, Thijs van Velzen, Teun J. de Vries, Robert Szulcek, Jack J. W. A. van Loon

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

In several diseases, bone resorption by osteoclasts is dysregulated. Thus far, no simple technique for real-time measurement of resorption is available. Here, we introduce an impedimetric bioassay for real-time monitoring of resorption by making use

Externí odkaz: https://doaj.org/article/cffc2a5da4434f02b05351321264cb40

Increase in the Number of Bone Marrow Osteoclast Precursors at Different Skeletal Sites, Particularly in Long Bone and Jaw Marrow in Mice Lacking IL-1RA

Autor: Giuliana Ascone, Yixuan Cao, Ineke D.C. Jansen, Irene Di Ceglie, Martijn H.J. van den Bosch, Arjen B. Blom, Peter L.E.M. van Lent, Vincent Everts, Teun J. de Vries

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 11, p 3774 (2020)

Recently, it was shown that interleukin-1β (IL-1β) has diverse stimulatory effects on different murine long bone marrow osteoclast precursors (OCPs) in vitro. In this study, interleukin-1 receptor antagonist deficient (Il1rn−/−) and wild-type (

Externí odkaz: https://doaj.org/article/da720f86e7904826b80b026330bc8d43

Endogenous expression and endocytosis of tartrate-resistant acid phosphatase (TRACP) by osteoblast-like cells

Autor: Ton Schoenmaker, Jussi M. Halleen, Vincent Everts, Sari L. Alatalo, S. Perez-Amodio, Wouter Beertsen, Ilse M. C. Vogels, D.C. Jansen

Publikováno v: Perez Amodio, S G, Vogels, I M, Schoenmaker, A M, Jansen, D C, Alatalo, S L, Halleen, J M, Beertsen, W & Everts, V 2005, ' Endogenous expression and endocytosis of tartrate-resistant acid phosphatase (TRACP) by osteoblast-like cells ', Bone, vol. 36, pp. 1065-1077 . https://doi.org/10.1016/j.bone.2005.03.005
Bone, 36, 1065-1077. Elsevier
Bone, 36(6), 1065-1077. Elsevier Inc.
Bone, 36, 1065-1077. Elsevier Inc.

Tartrate-resistant acid phosphatase (TRACP) is produced by macrophages and other cells of the monohistiocytic lineage. In particular, osteoclasts are characterized for a high expression of this enzyme. Yet, several data suggest that other bone cell t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bf23fd3b42e2b2dbfd1e4d6696b548
https://hdl.handle.net/11245/1.249362

Participation of intracellular cysteine proteinases, in particular Cathepsin B, in degradation of collagen in periosteal tissue explants

Autor: David J. Buttle, Kees A. Hoeben, Vincent Everts, D.C. Jansen, Laura B. Creemers, W. Beertsen

Publikováno v: Matrix biology, 16(9), 575-584. Elsevier
Matrix Biology, 16, 575-584. Elsevier

The involvement of cysteine proteinases in the degradation of soft connective tissue collagen was studied in cultured periosteal explants. Using cysteine proteinase inhibitors that were active intracellularly or extracellularly (Ep453 and Ep475, resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b611072c2615934b4c30f67e7edb6c9b
https://doi.org/10.1016/S0945-053X(98)90068-3

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