Zobrazeno 1 - 10
of 159
pro vyhledávání: '"D.B. Clayson"'
Autor:
Fraser W. Scott, Eric Lok, D.B. Clayson, E.A. Nera, P. Jee, E. McMullen, W.M.N. Ratnayake, S. Fernie
Publikováno v:
Cancer Letters. 92:229-234
In previous work we have shown that changing the fatty acid composition of a constant amount of fat in a modified AIN-76A diet affected the level of ductular cell proliferation in the mammary glands of young virgin female Swiss Webster mice. In parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe9fc294894b69ed9e50d50c1060fcb
https://doi.org/10.1016/0304-3835(95)03803-5
https://doi.org/10.1016/0304-3835(95)03803-5
Autor:
E. McMullen, E. Lok, W.M.N. Ratnayake, S. Fernie, Fraser W. Scott, R. Mongeau, E.A. Nera, P. Jee, D.B. Clayson, S. Malcolm
Publikováno v:
Carcinogenesis. 13:1735-1741
Young virgin female Swiss Webster mice were fed AIN-76A semi-purified diets containing equal weights of different fats for approximately 30 days. Using [3H]thymidine radioautography, it was established that mice fed 100% lard or high levels of fish o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f4ef666e67003d97bf4cfad7e58c3a
https://doi.org/10.1093/carcin/13.10.1735
https://doi.org/10.1093/carcin/13.10.1735
Autor:
Helen Tryphonas, Stephen Hayward, D. Miller, Eric Lok, Rekha Mehta, F. Lacroix, D.B. Clayson, P. Jee
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 37(7)
Selected immune function parameters were examined in male Fischer 344 rats following (a) induction of enzyme-altered preneoplastic liver foci (EAF), and (b) growth modulation of EAF by 30-day feeding with the food antioxidant butylated hydroxytoluene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fbb007b242e553f9ae7ca69e19a4e7
https://pubmed.ncbi.nlm.nih.gov/10496368
https://pubmed.ncbi.nlm.nih.gov/10496368
Publikováno v:
Carcinogenesis. 16(5)
Butylated hydroxytoluene (BHT) is a synthetic, food-use, phenolic antioxidant. It has previously been demonstrated to be operationally non-genotoxic and, in addition, failed to induce biologically significant increases in cellular proliferation in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5879797e8612bbf0fa73aef5d1b689
https://pubmed.ncbi.nlm.nih.gov/7767967
https://pubmed.ncbi.nlm.nih.gov/7767967
Autor:
E. McMullen, M. Chiba, D.B. Clayson, E.A. Nera, P. Jee, R. Cerkauskas, R. Brassard, R. Mongeau, Eric Lok
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 32(3)
Umbelliferous crop plants, including the parsnip (Pastinaca sativa L.), elaborate enhanced levels of furocoumarins, including psoralens, when subjected to biotic or abiotic stress. These furocoumarins are recognized to lead to phototoxicity. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9306e01c67655190760109f2123ebabe
https://pubmed.ncbi.nlm.nih.gov/8157221
https://pubmed.ncbi.nlm.nih.gov/8157221
Autor:
D.B. Clayson
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 17(2 Pt 1)
Those chemicals that are added to food during modern processing are most stringently examined for toxic effects and, if they demonstrate toxicity, are strictly controlled. Despite this, a considerable proportion of the North American human cancer bur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdab5665b9f810fca796b47591be4bd
https://pubmed.ncbi.nlm.nih.gov/8484024
https://pubmed.ncbi.nlm.nih.gov/8484024
Autor:
Daniel Krewski, D.B. Clayson
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 167:233-240
The problems that arise in the interpretation of experimental data on chemical carcinogenesis are addressed. In particular, the difficulties in demonstrating negative results are shown to present problems in delineating carcinogens from noncarcinogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d65ade3e4a1b9fec43866a6c028a35be
https://doi.org/10.1016/0165-1110(86)90032-1
https://doi.org/10.1016/0165-1110(86)90032-1
Publikováno v:
Chemico-Biological Interactions. 6:107-118
The structural features of 4-ethylsulphonylnaphthalene-1-sulphonamide (ENS) responsible for the induction of DNA synthesis in the mouse bladder have been investigated using a method in which DNA synthesis is measured by the uptake of a thymidine anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1396d4bc8c9357a82998709d6cfccf90
https://doi.org/10.1016/0009-2797(73)90077-x
https://doi.org/10.1016/0009-2797(73)90077-x
Autor:
D.B. Clayson, J.J. Childs
Publikováno v:
Biochemical Pharmacology. 15:1247-1258
The seven known monohydroxy-derivatives of 1-phenylazo-2-naphthol may be separated by thin film chromatography on silica plates by the use of two solvent systems. The metabolites of 1-phenylazo-2-naphthol in the bile and urine of the rabbit have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f9f7abf74d820196f85e1efadb59dd6
https://doi.org/10.1016/0006-2952(66)90034-7
https://doi.org/10.1016/0006-2952(66)90034-7
Publikováno v:
Biochemical Pharmacology. 16:1555-1561
1-Amino-2-naphthyl hydrogen sulphate, 1-amino-2-naphthyl glucuronide and the glucuronide of 1-phenylhydrazo-2-naphthol are present in the urine of rats treated with 1-phenylazo-2-naphthol. Both the bile and the urine contain the glucuronides of 4'—
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1387cf151050dc1ec824a5b6912c014
https://doi.org/10.1016/0006-2952(67)90133-5
https://doi.org/10.1016/0006-2952(67)90133-5