Zobrazeno 1 - 10
of 421
pro vyhledávání: '"D.B. Calne"'
Volume 5 of the series'Advances in Research on Neurodegeneration'is concerned with themes which are currently the focus of intensive research, and in which advances in our understanding of the pathological mechanisms un derlying neurodegenerative d
Neurodegeneration is one of the most important subjects of the investigation now and in the coming 21st century. Alzheimer's disease is the leading cause of dementia in the elderly people and Parkinson's disease is one of the major neurologic disorde
Publikováno v:
Parkinsonism & Related Disorders. 6:205-214
We describe Parkinsonism in prominent people, where Wilhelm von Humboldt and Adolf Hitler provide just two spectacular, opposing examples. In both of them, there is little if any evidence that the disease did influence their life ambitions, methods o
We organized the Seventh International Winter Conference on Neurodegeneration and Neuroinflammation in a small town of Karuizawa in Nagano Prefecture in Japan on January 20 to 22, 1999. Karuizawa is a nice summer as well as winter resort close to the
Autor:
D.B. Calne, H. Shinotoh
Publikováno v:
Brain and cognition. 28(3)
Activation studies with positron emission tomography (PET) have provided an understanding of the pathophysiology of akinesia and tremor in Parkinsons disease (PD). [F-18]6-fluoro-L-dopa (FD)-PET and dopamine receptor imaging by PET can assist in the
Autor:
D.B. Calne
Publikováno v:
Parkinsonism & Related Disorders. 12:1
Autor:
A. Petrie, C.A. Pallis, L. Haskayne, D.B. Calne, L. E. Claveria, I.C. Lodge-Patch, P.F. Teychenne
Publikováno v:
Journal of the Neurological Sciences. 24:393-401
We have investigated the action of pimozide in tardive dyskinesia induced by prolonged administration of phenothiazines. Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18.8 mg/day) for 6 we
Publikováno v:
British Journal of Clinical Pharmacology. 3:571-574
The cardiovascular effects of bromocriptine, a dopamine receptor agonist, were investigated in twenty-eight Parkinsonian patients. Bromocriptine caused a significant impairment of postural compensation with a fall in systolic pressure and an absence
Publikováno v:
Electroencephalography and Clinical Neurophysiology. 26:86-92
Tremor has been studied by summing electromyographic signals in an averaging computer. Such analyses afford precise comparison of the mean patterns of activity in different groups of muscles. Complex movements such as "pill-rolling" involve synchrono