Liposome induction of CD8+ T cell responses depends on CD169+ macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion

Autor: L. Klaase, Paul R. Crocker, M.K. Nijen Twilhaar, Katarzyna Olesek, D.A.M. Heijnen, Gert Storm, Martino Ambrosini, Alsya J. Affandi, J.M.M. den Haan, Andrés Hidalgo, K. Asano, Y van Kooyk, D. van Dinther, Joanna Grabowska, Leoni Hoogterp

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Grabowska, J, Affandi, A J, van Dinther, D, Nijen Twilhaar, M K, Olesek, K, Hoogterp, L, Ambrosini, M, Heijnen, D A M, Klaase, L, Hidalgo, A, Asano, K, Crocker, P R, Storm, G, van Kooyk, Y & den Haan, J M M 2021, ' Liposome induction of CD8 + T cell responses depends on CD169 + macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion ', Journal of Controlled Release, vol. 331, pp. 309-320 . https://doi.org/10.1016/j.jconrel.2021.01.029
Journal of controlled release : official journal of the Controlled Release Society, 331, 309. Elsevier
Journal of controlled release, 331, 309-320. Elsevier
Journal of Controlled Release, 331, 309-320. Elsevier

Cancer vaccines aim to efficiently prime cytotoxic CD8+ T cell responses which can be achieved by vaccine targeting to dendritic cells. CD169+ macrophages have been shown to transfer antigen to dendritic cells and could act as an alternative target f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd3465606d06b7513ccd028efc441eb
https://dspace.library.uu.nl/handle/1874/418106

Cerebrospinal fluid anti-whole myelin antibodies are not correlated to magnetic resonance imaging activity in multiple sclerosis

Autor: Tewarie, P., Teunissen, C.E., Dijkstra, C.D., D.A.M., Heijnen, Vogt, M., Balk, L., Vrenken, H., Polman, C.H., Killestein, J.

Publikováno v: In Journal of Neuroimmunology 15 October 2012 251(1-2):103-106

The Release of Cytokines by Macrophages Is Not Affected by Myelin Ingestion

Autor: D.A.M. Heijnen, E.J.F. Vereyken, Christine D. Dijkstra, J.J. Garcia Vallejo, Judith E. Glim

Publikováno v: GLIA, 58(16), 1928-1936. John Wiley and Sons Inc.
Glim, J E, Vereyken, E J F, Heijnen, D A M, Garcia Vallejo, J J & Dijkstra, C D 2010, ' The Release of Cytokines by Macrophages Is Not Affected by Myelin Ingestion ', GLIA, vol. 58, no. 16, pp. 1928-1936 . https://doi.org/10.1002/glia.21062

Macrophages play an important role in demyelination in multiple sclerosis (MS). Activated macrophages ingest myelin particles, thereby acquiring a foamy appearance. Foamy macrophages in MS lesions were described as being anti-inflammatory. Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fe33ba35b514feab5978ad56b98ecf
https://research.vumc.nl/en/publications/81eb3c14-5ca1-4784-9f27-7cee5355dc25

Changes in characteristics of rat skeletal muscle after experimental allergic encephalomyelitis

Autor: M.R. van der Vliet, A. de Haan, Christine D. Dijkstra, Jerome J. A. Hendriks, D.A.M. Heijnen

Publikováno v: Muscle and Nerve, 29(3), 369-75. John Wiley & Sons, Inc.
de Haan, A, van der Vliet, M R, Hendriks, JJ, Heijnen, DA & Dijkstra, C D 2004, ' Changes in characteristics of rat skeletal muscle after experimental allergic encephalomyelitis. ', Muscle and Nerve, vol. 29, no. 3, pp. 369-75 . https://doi.org/10.1002/mus.10554

Experimental allergic encephalomyelitis (EAE) serves as an animal model for certain neuroinflammatory diseases of the central nervous system, in particular multiple sclerosis (MS). EAE is accompanied by transient weakness or paralysis of hind limbs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47879ef3d67767ff9ecb790f7719e1e9
https://research.vu.nl/en/publications/feef524f-39f1-476c-9dcc-05be4bb3d78f

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