Zobrazeno 1 - 10
of 84
pro vyhledávání: '"D.A. Veselkov"'
Autor:
Mark R. Sanderson, Trishant R. Umrekar, L. Mark Fisher, Galyna B. Skamrova, X.-S. Pan, D.A. Veselkov, Ivan Laponogov
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Laponogov, I, Pan, X S, Veselkov, D A, Skamrova, G B, Umrekar, T R, Fisher, L M & Sanderson, M R 2018, ' Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase ', Nature Communications, vol. 9, no. 1, 2579 . https://doi.org/10.1038/s41467-018-05005-x
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Laponogov, I, Pan, X S, Veselkov, D A, Skamrova, G B, Umrekar, T R, Fisher, L M & Sanderson, M R 2018, ' Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase ', Nature Communications, vol. 9, no. 1, 2579 . https://doi.org/10.1038/s41467-018-05005-x
Type II topoisomerases alter DNA topology to control DNA supercoiling and chromosome segregation and are targets of clinically important anti-infective and anticancer therapeutics. They act as ATP-operated clamps to trap a DNA helix and transport it
Autor:
Ryan Cirz, D.A. Veselkov, X.-S. Pan, Heinz E. Moser, Isabelle M.-T. Crevel, Art Branstrom, Mark R. Sanderson, Ivan Laponogov, L. Mark Fisher, Jogitha Selvarajah
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1798ea4dbd69d476b9c8c0cbd8ac8d
https://openaccess.sgul.ac.uk/id/eprint/111159/1/a55730.pdf
https://openaccess.sgul.ac.uk/id/eprint/111159/1/a55730.pdf
Autor:
Ivan Laponogov, L. Mark Fisher, Mark R. Sanderson, D.A. Veselkov, Xiao-Su Pan, Isabelle M.-T. Crevel
Publikováno v:
Nucleic Acids Research
Type II topoisomerases regulate DNA supercoiling and chromosome segregation. They act as ATP-operated clamps that capture a DNA duplex and pass it through a transient DNA break in a second DNA segment via the sequential opening and closure of ATPase-
Autor:
D.A. Veselkov, David B. Davies, Maxim P. Evstigneev, A. A. Hernandez Santiago, Alexei N. Veselkov
Publikováno v:
Journal of Molecular Structure. 690:17-24
The self-association of a bis-intercalator, ethidium homodimer (EBH), and its hetero-association with phenanthridine dye, propidium iodide (PI), have been studied by 1D and 2D 1 H NMR spectroscopy using the analysis of proton chemical shifts changes
Autor:
Katherine McAuley, X.-S. Pan, A.W. Thompson, D.A. Veselkov, M.K. Sohi, L.M. Fisher, Mark R. Sanderson, Ivan Laponogov, R. Sawhney
Publikováno v:
Nature Structural & Molecular Biology. 16:667-669
Type II topoisomerases alter DNA topology by forming a covalent DNA-cleavage complex that allows DNA transport through a double-stranded DNA break. We present the structures of cleavage complexes formed by the Streptococcus pneumoniae ParC breakage-r
Autor:
Zhisheng Lu, Torsten Schaller, Yi Yang, Mark R. Sanderson, D.A. Veselkov, Julien R. C. Bergeron, Alain Oregioni, R. Andrew Atkinson, Michael H. Malim, Stephen Matthews
Publikováno v:
Open Biology, Vol 3, Iss 11 (2013)
Open Biology
Open Biology
The HIV-1 viral infectivity factor (Vif) neutralizes cell-encoded antiviral APOBEC3 proteins by recruiting a cellular ElonginB (EloB)/ElonginC (EloC)/Cullin5-containing ubiquitin ligase complex, resulting in APOBEC3 ubiquitination and proteolysis. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dcc79b871013dac86878d1314b674a
http://hdl.handle.net/10044/1/77389
http://hdl.handle.net/10044/1/77389
Autor:
D.A. Veselkov, Rebecca L. Beavil, Stephen Matthews, Julien R. C. Bergeron, Mark R. Sanderson, Michael H. Malim, Hendrik Huthoff, Peter Simpson
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000925 (2010)
PLoS Pathogens
PLoS Pathogens
The HIV-1 viral infectivity factor (Vif) protein recruits an E3 ubiquitin ligase complex, comprising the cellular proteins elongin B and C (EloBC), cullin 5 (Cul5) and RING-box 2 (Rbx2), to the anti-viral proteins APOBEC3G (A3G) and APOBEC3F (A3F) an
Autor:
Mark R. Sanderson, L. Mark Fisher, Katherine McAuley, Ivan Laponogov, D.A. Veselkov, X.-S. Pan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11338 (2010)
PLoS ONE, Vol 5, Iss 6, p e11338 (2010)
Type II DNA topoisomerases are ubiquitous enzymes with essential functions in DNA replication, recombination and transcription. They change DNA topology by forming a transient covalent cleavage complex with a gate-DNA duplex that allows transport of
Autor:
L. Mark Fisher, Katherine McAuley, D.A. Veselkov, Mark R. Sanderson, Ivan Laponogov, X.-S. Pan
Publikováno v:
PLoS ONE, Vol 5, Iss 7 (2010)
PLoS ONE
PLoS ONE
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 9, p e3201 (2008)
PLoS ONE, Vol 3, Iss 9, p e3201 (2008)
BACKGROUND: Streptococcus pneumoniae is the major cause of community-acquired pneumonia and is also associated with bronchitis, meningitis, otitis and sinusitis. The emergence and increasing prevalence of resistance to penicillin and other antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f51180a10a7a739dc28c7f08fbb9231
http://hdl.handle.net/10044/1/38507
http://hdl.handle.net/10044/1/38507