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Disturbed gut microbiota and bile homeostasis in Giardia -infected mice contributes to metabolic dysregulation and growth impairment.

Autor: Riba A; Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany., Hassani K; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, 30625 Hannover, Germany., Walker A; Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München, 85764 Neuherberg, Germany., van Best N; Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany.; Department of Medical Microbiology and NUTRIM, Maastricht University, Maastricht, Netherlands., von Zezschwitz D; Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany., Anslinger T; Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany., Sillner N; Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München, 85764 Neuherberg, Germany.; ZIEL Institute for Food and Health, Technical University of Munich, 85354 Freising, Germany., Rosenhain S; Institute for Experimental Molecular Imaging, University Hospital Aachen, 52074 Aachen, Germany., Eibach D; Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, 20359 Hamburg, Germany., Maiga-Ascofaré O; Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana., Rolle-Kampczyk U; Helmholtz Centre for Environmental Research, Department of Molecular Systems Biology, 04318 Leipzig, Germany., Basic M; Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany., Binz A; Institute of Virology, Hannover Medical School, 30625 Hannover, Germany., Mocek S; Chair for Molecular Nutritional Medicine, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany., Sodeik B; Institute of Virology, Hannover Medical School, 30625 Hannover, Germany., Bauerfeind R; Research Core Unit for Laser Microscopy, Hannover Medical School, 30625 Hannover, Germany., Mohs A; Medizinische Klinik III, RWTH University Hospital, Aachen, 52074 Aachen, Germany., Trautwein C; Medizinische Klinik III, RWTH University Hospital, Aachen, 52074 Aachen, Germany., Kiessling F; Institute for Experimental Molecular Imaging, University Hospital Aachen, 52074 Aachen, Germany.; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.; Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany., May J; Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, 20359 Hamburg, Germany., Klingenspor M; Chair for Molecular Nutritional Medicine, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany., Gremse F; Institute for Experimental Molecular Imaging, University Hospital Aachen, 52074 Aachen, Germany.; Software Tools for Computational Engineering, RWTH Aachen University, 52072 Aachen, Germany.; Gremse-IT GmbH, 52068 Aachen, Germany., Schmitt-Kopplin P; Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München, 85764 Neuherberg, Germany.; ZIEL Institute for Food and Health, Technical University of Munich, 85354 Freising, Germany.; Analytical Food Chemistry, Technical University of Munich, 85354 Freising, Germany., Bleich A; Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany., Torow N; Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany., von Bergen M; Helmholtz Centre for Environmental Research, Department of Molecular Systems Biology, 04318 Leipzig, Germany.; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Bruderstrase 34, D-04103 Leipzig, Germany., Hornef MW; Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany. mhornef@ukaachen.de.

Publikováno v: Science translational medicine [Sci Transl Med] 2020 Oct 14; Vol. 12 (565).