Zobrazeno 1 - 10
of 24
pro vyhledávání: '"D. den Brok"'
Autor:
C. Callenberg, A. Lyons, D. den Brok, A. Fatima, A. Turpin, V. Zickus, L. Machesky, J. Whitelaw, D. Faccio, M. B. Hullin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Imaging across both the full transverse spatial and temporal dimensions of a scene with high precision in all three coordinates is key to applications ranging from LIDAR to fluorescence lifetime imaging. However, compromises that sacrifice,
Externí odkaz:
https://doaj.org/article/3e1b87eb10214096987243d291398579
Autor:
Anna V. Tinker, Sophie Sun, Samuel Aparicio, Eric Y. Zhao, Wendie D. den Brok, Karen A. Gelmon, Kasmintan A. Schrader
Publikováno v:
JCO precision oncology. 1
BRCA1 and BRCA2 germline mutation–associated breast cancers are known to be deficient in the process of homologous recombination and often respond favorably to drugs targeting this important DNA repair pathway. There is emerging evidence that a sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc74c6746ce47ed86e266be79049207d
https://pubmed.ncbi.nlm.nih.gov/35172494
https://pubmed.ncbi.nlm.nih.gov/35172494
Autor:
Cynthia L. Toze, Kevin W. Song, Diego Villa, David W. Scott, Alina S. Gerrie, Laurie H. Sehn, Kerry J. Savage, Ciara L. Freeman, Wendie D. den Brok
Publikováno v:
Blood Adv
Rituximab-containing chemotherapy regimens constitute standard first-line therapy for mantle cell lymphoma (MCL). Since June 2013, 190 patients ≥18 years of age with MCL in British Columbia have been treated with bendamustine and rituximab (BR). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f712a3b7a407018cd8acfd69e9688158
https://pubmed.ncbi.nlm.nih.gov/32735654
https://pubmed.ncbi.nlm.nih.gov/32735654
Autor:
Emily Baxter, Wendie D. den Brok, Caroline A. Lohrisch, Scott Tyldesley, Caroline Speers, Lovedeep Gondara
Publikováno v:
Breast Cancer Research and Treatment. 161:549-556
Purpose We hypothesized different Overall Survival (OS) in metastatic breast cancer (MBC) after relapse vs de novo presentation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a724e96a4c9943ff87509971b4f10a
https://doi.org/10.1007/s10549-016-4080-9
https://doi.org/10.1007/s10549-016-4080-9
Autor:
Diego Villa, Pinaki Bose, Caroline Lohrisch, Carolyn Ch'ng, Wendie D. den Brok, Richard Corbett, Aly Karsan, Ian Bosdet, Howard John Lim, Tamara Shenkier, Sheridan Wilson, Richard A. Moore, Stephen Chia, Eric Y. Zhao, Karen A. Gelmon, Marco A. Marra, Daniel J. Renouf, Stephen Yip, Martin Jones, Yongjun Zhao, Erin Pleasance, Sophie Sun, Karen Mungall, Caralyn Reisle, Sreeja Leelakumari, Nina Thiessen, Kasmintan A. Schrader, Yaoqing Shen, Peter Eirew, Jacqueline E. Schein, Steven J.M. Jones, Andrew J. Mungall, Janessa Laskin, Yussanne Ma, Sean D. Young, Katayoon Kasaian
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 23(24)
Purpose: Recent studies have identified mutation signatures of homologous recombination deficiency (HRD) in over 20% of breast cancers, as well as pancreatic, ovarian, and gastric cancers. There is an urgent need to understand the clinical implicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565132945d28d9bceb27a4fdca7475b4
https://pubmed.ncbi.nlm.nih.gov/29246904
https://pubmed.ncbi.nlm.nih.gov/29246904
Autor:
Wendie-Lou D. Den Brok, Gondara Lovedeep, Scott Tyldesley, Caroline Speers, Lohrisch Caroline, Emily Baxter
Publikováno v:
Cancer Research. 75:P6-08
Introduction: Median overall survival (OS) for patients (pts) with metastatic breast cancer (MBC) is described as 2-3 years, but few reports compare OS for de novo versus relapsed disease. The recognized clinical subtypes of breast cancer (HR positiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2451915a31b5892acd203638539c697c
https://doi.org/10.1158/1538-7445.sabcs14-p6-08-40
https://doi.org/10.1158/1538-7445.sabcs14-p6-08-40
Autor:
Karen A. Gelmon, Wendie D. den Brok
Publikováno v:
Medical Research Archives. 4
Background: Triple-negative breast cancer (TNBC) is an aggressive, heterogeneous clinical breast cancer subtype that currently lacks approved targeted therapies. Research aimed at understanding the mutational and transcriptional landscape of TNBC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f7db88dfa0020af3a16e0d6ffa654d0
https://doi.org/10.18103/mra.v4i6.707
https://doi.org/10.18103/mra.v4i6.707
Autor:
Wendie D. den Brok, Caroline A. Lohrisch, Lovedeep Gondara, Scott Tyldesley, Caroline Speers, Emily Baxter
Publikováno v:
Breast Cancer Research and Treatment. 162:397-398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ea51e547b7011f4eec15755097b013
https://doi.org/10.1007/s10549-017-4114-y
https://doi.org/10.1007/s10549-017-4114-y
Autor:
Alan Nichol, Caroline Speers, Wendie-Lou D. Den Brok, Christine Wilson, Caroline A. Lohrisch, Lovedeep Gondara
Publikováno v:
Journal of Clinical Oncology. 35:1544-1544
1544 Background: There is ongoing debate about the role of screening mammography and its impact on overall survival in breast cancer. We hypothesized that women with screen-detected breast cancers (SDBC) receive less surgery, regional radiotherapy (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b1277d3cce2faef30b8a65e1b72062
https://doi.org/10.1200/jco.2017.35.15_suppl.1544
https://doi.org/10.1200/jco.2017.35.15_suppl.1544
Autor:
Steve Kalloger, Mar Mar, Peter Eirew, Karen A. Gelmon, Samuel Aparicio, Wendie D. den Brok, Cherie Bates, Stephen Chia
Publikováno v:
Cancer Research. 76:638-638
Purpose: We have expertise in breast cancer xenograft models and have previously published data on clonal dynamics. Our aim was to explore clinical characteristics of those patients (pts) whose breast cancer tumours engrafted versus those that did no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::161c5bfb00227e873f9c01d306ddda29
https://doi.org/10.1158/1538-7445.am2016-638
https://doi.org/10.1158/1538-7445.am2016-638