Zobrazeno 1 - 10
of 17
pro vyhledávání: '"D. Yu. Gvaldin"'
Autor:
D. Yu. Gvaldin, N. A. Petrusenko, E. E. Rostorguev, S. N. Dimitriadi, S. E. Kavitskiy, N. N. Timoshkina
Publikováno v:
Issledovaniâ i Praktika v Medicine, Vol 11, Iss 2, Pp 36-45 (2024)
Against the background of modest successes in the development of new diagnostic and therapeutic tools to improve the survival of patients with glial brain tumors, early diagnosis of this pathology remains relevant. Endogenous noncoding miRNAs that re
Externí odkaz:
https://doaj.org/article/3d8bbed8ff304932ab34b2878491f63c
Publikováno v:
Сеченовский вестник, Vol 14, Iss 2, Pp 49-56 (2023)
In colorectal cancer (CRC) in addition to the most common mutations in the second exon of KRAS, there are rarer mutations that are not well understood as prognostic markers.Description of cases. We describe two clinical cases of moderately differenti
Externí odkaz:
https://doaj.org/article/5485fbd43c9f4c94a516721f530aeef6
Autor:
O. I. Kit, I. A. Novikova, N. N. Timoshkina, D. Yu. Gvaldin, A. A. Pushkin, O. Yu. Kaimakchi, A. A. Maslov, A. V. Shaposhnikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 1, Pp 49-56 (2023)
Introduction. Colorectal cancer is a frequently diagnosed disease being in the third place among oncological diseases both in incidence and mortality. Currently, researchers focus on development of more accessible and reliable biomarkers of colorecta
Externí odkaz:
https://doaj.org/article/61ce49c2d8a1483092904d86bc03a78c
Autor:
A. S. Goncharova, E. N. Kolesnikov, G. Yu. Egorov, A. Yu. Maksimov, A. N. Shevchenko, E. M. Nepomnyashchaya, D. Yu. Gvaldin, L. Z. Kurbanova, D. V. Khodakova, S. O. Kit, O. Yu. Kaymakchi, A. V. Snezhko
Publikováno v:
Бюллетень сибирской медицины, Vol 21, Iss 4, Pp 37-43 (2023)
The aim of the study was to create a patient-derived xenograft (PDX) model of human colorectal cancer and to determine its histologic and molecular characteristics, such as the status of KRAS, NRAS, and BRAF genes and the presence of microsatellite i
Externí odkaz:
https://doaj.org/article/2b88c128ea1a4eec8bd36dce5ae9c80c
Autor:
A. A. Pushkin, D. Yu. Gvaldin, N. N. Timoshkina, E. E. Rostorguev, L. Yu. Vladimirova, E. A. Dzenkova
Publikováno v:
Issledovaniâ i Praktika v Medicine, Vol 9, Iss 1, Pp 54-64 (2022)
Purpose of the study. This work is devoted to the study of blood plasma miRNA patterns in blood plasma using high-throughput sequencing of the Omnibus Gene Expression base and the search for candidate miRNA molecules for the development of a minimall
Externí odkaz:
https://doaj.org/article/28da480f455b48de9dca66abfbd1fd5c
Publikováno v:
Issledovaniâ i Praktika v Medicine, Vol 8, Iss 3, Pp 21-33 (2021)
Purpose of the study. This research was devoted to study of mRNA and miRNA expression patterns in glioglastomas using The Cancer Genome Atlas (TCGA) data, to search for genetic determinants that determine the prognosis of patient survival and to crea
Externí odkaz:
https://doaj.org/article/bb9b6472c5dc46738b5b452f3f3981b5
Autor:
D. Yu. Gvaldin, N. N. Timoshkina, L. N. Vashchenko, I. A. Novikova, L. Yu. Vladimirova, A. E. Storozhakova, A. B. Sagakyants
Publikováno v:
Russian Clinical Laboratory Diagnostics. 67:123-128
The purpose of this study was to research the effectiveness of molecular genetic tests based on the determination of the rs4673 CYBA polymorphism (c.242C>T) and the level of paraoxonase 1 (PON1) in the blood plasma of patients with breast cancer (BC)
Autor:
Eduard E. Rostorguev, Irina V. Mezhevova, D. Yu. Gvaldin, Tatiana V. Shamova, Natalya N. Timoshkina, Sofia V. Timofeeva, Anastasia O. Sitkovskaya, S. Yu. Filippova
Publikováno v:
Crimea Journal of Experimental and Clinical Medicine. 10:39-42
Glial tumors, in particular those composed of astrocytes, are the most common group of primary brain tumors. The most common glial tumor is astrocytoma. The biology of glial tumors was routinely studied on immortalized cell lines. However, multiple p
Publikováno v:
Russian Journal of Genetics. 56:142-158
Neuroendocrine tumors (NETs) account for less than 3% of primary neoplasias of the pancreas. Despite success of the classification, the discovery of new methods of treatment, and innovations in the field of visualization, non-aeroendocrine neoplasms
Autor:
I. F. Shlyk, V. V. Vnukov, N. S. Doltmurzieva, A. A. Plotnikov, N. P. Milyutina, R. V. Sidorov, A. A. Ananyan, D. Yu. Gvaldin, D. Yu. Pospelov
Publikováno v:
Advances in Gerontology. 9:426-433
To study the role of paraoxonase, myeloperoxidase, arginase, asymmetric dimethylarginine, and nitric oxide in the mechanisms of the pathogenesis of postpericardiotomy syndrome (PPCS), 76 patients with ischemic heart disease (IHD) who underwent corona