Zobrazeno 1 - 10
of 16
pro vyhledávání: '"D. Ya. Havrylyuk,"'
Autor:
Kh. V. Malysheva, N. S. Finiuk, O. K. Pavlenko, D. Ya. Havrylyuk,, R. B. Lesyk, R. S. Stoika, O. G. Korchynskyi
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss SI01, Pp 111-122 (2017)
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of yet unknown etiology. Tumor necrosis factor α (TNFα) is recognized as a regulatory substance that plays a central role in RA development and progression. On the other side, the bone
Externí odkaz:
https://doaj.org/article/cb4e3b20ae71473b973cecfb8449c47e
Autor:
L. I. Kоbylinska, D. Ya. Havrylyuk, N. E. Mitina, A. S. Zаichenko, R. B. Lesyk, B. S. Zіmenkovsky, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 1, Pp 51-60 (2016)
The aim of this study was to compare the effect of new synthetic 4-thiazolidinone derivatives (potential anticancer compounds denoted as 3882, 3288 and 3833) and doxorubicin (positive control) in free form and in their complexes with synthetic polyet
Externí odkaz:
https://doaj.org/article/0999cf764c03446a89d263f47e0c1a47
Autor:
L. I. Kоbylinska, D. Ya. Havrylyuk, А. О. Ryabtseva, N. E. Mitina, О. S. Zаichenko, R. B. Lesyk, B. S. Zіmenkovsky, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 2, Pp 122-132 (2015)
The aim of this study was to compare the effect of new synthetic 4-tiazolidinone derivatives (compounds 3882, 3288 and 3833) and doxorubicin (positive control) in free form and in their complexes with synthetic polyethyleneglycol-containing nanoscale
Externí odkaz:
https://doaj.org/article/535dc5db2a9149439e6172359ecad216
Autor:
N. M. Boiko, O. Yu. Klyuchivska, L. I. Коbylinska, D. Ya. Havrylyuk, A. O. Ryabtseva, N. Ye. Mitina, R. B. Lesyk, O. S. Zаichenko, R. S. Stoika
Publikováno v:
Biotechnologia Acta, Vol 8, Iss 1, Pp 39-48 (2015)
A nanoscale polymeric carrier was used for delivery of novel anticancer compounds – 4-tiazolidinone derivatives – to tumor cells of different lines. It was found that such way of delivery of the above mentioned compounds to target cells significa
Externí odkaz:
https://doaj.org/article/b26f9f4f109348758735d23cf6e44049
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 6, Pp 96-105 (2014)
Pyrazole- and aryl-substituted derivatives of 4-thiazolidinone belong to a perspective group of compounds with potential antitumor action. Earlier, we have demonstrated high toxicity in vitro of several 4-thiazolidinones derivatives towards tumor cel
Externí odkaz:
https://doaj.org/article/762caed23b734102aa1c79dbfcf5bbae
Autor:
L. I. Kоbylinska, D. Ya. Havrylyuk, А. О. Ryabtseva,, N. E. Mitina, О. S. Zаichenko, B. S. Zіmenkovsky, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 6, Pp 84-95 (2014)
The aim of this study was to measure the activity of enzymes which reflect cardiotoxic action in rats of novel synthetic 4-thiazolidone derivatives – 3882, 3288 and 3833 that demonstrated antineoplastic effect in vitro towards 60 lines of human tum
Externí odkaz:
https://doaj.org/article/2f623843b15247488d5d50844481ca02
Autor:
V. V. Chumak, R. R. Panchuk, N. O. Manko, D. Ya. Havrylyuk, R. V. Lesyk, L. I. Kobylinska, B. S. Zimenkovsky, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 8, Iss 2, Pp 29-42 (2014)
Compounds on the basis of 4-thiazolidinone and its isatin-containing derivatives are characterized by a broad spectrum of biological activities and are potential antineoplastic agents. We have shown that the combination of 4-thiazolidinone and isatin
Externí odkaz:
https://doaj.org/article/6b94ba341ffa4a289115694e01d4b178
Autor:
N. S. Finiuk, O. G. Korchynsky, O. K. Pavlenko, Kh. V. Malysheva, Rostyslav Stoika, Roman Lesyk, D. Ya. Havrylyuk
Publikováno v:
Ukrainian Biochemical Journal, Vol 89, Iss SI01, Pp 111-122 (2017)
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of yet unknown etiology. Tumor necrosis factor α (TNFα) is recognized as a regulatory substance that plays a central role in RA development and progression. On the other side, the bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7c32341904b51db4ff170f177ea2bd
https://doi.org/10.15407/ubj89.si01.111
https://doi.org/10.15407/ubj89.si01.111
Autor:
Nataliya Mitina, L I Kоbyli nska, Alexander Zaichenko, B S Zіme nkovsky, Rostyslav Stoika, D. Ya. Havrylyuk, Roman Lesyk
Publikováno v:
Ukrainian Biochemical Journal, Vol 88, Iss 1, Pp 51-60 (2016)
The aim of this study was to compare the effect of new synthetic 4-thiazolidinone derivatives (potential anticancer compounds denoted as 3882, 3288 and 3833) and doxorubicin (positive control) in free form and in their complexes with synthetic polyet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59054e49a74bfabd95d2dc5b000a1594
https://pubmed.ncbi.nlm.nih.gov/29227079
https://pubmed.ncbi.nlm.nih.gov/29227079
Autor:
D. Ya. Havrylyuk
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 12:59-64
The application of the [2+3]-cyclocondensation reaction for the synthesis of 2-pyrazoline substituted thiazolidinones, as well as bioisosteric pyrazoline-thiazoles has been analyzed. Following the literature data 4,5-dihydro- 1-carbothioamides are us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d27d3cea9dcaa328b321212c31d2a7e0
https://doi.org/10.24959/ophcj.14.797
https://doi.org/10.24959/ophcj.14.797