Zobrazeno 1 - 10
of 745
pro vyhledávání: '"D. Wesley"'
Publikováno v:
The Cryosphere, Vol 17, Pp 5283-5297 (2023)
The Mackenzie River delta is the second largest Arctic river delta in the world. Thin and destabilizing permafrost coupled with vast natural gas reserves at depth, high organic-content soils, and a high proportion of wetlands create a unique ecosyste
Externí odkaz:
https://doaj.org/article/e30a8c4c13054025a5272f88f2bb2b0a
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Due to its viscoelastic properties, the aorta aids in dampening blood pressure pulsatility. At the level of resistance-arteries, the pulsatile flow will be transformed into a continuous flow to allow for optimal perfusion of end organs such as the ki
Externí odkaz:
https://doaj.org/article/683eb2058dc74387803314d873822cd9
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antigen-specific immunotherapy (ASI) holds great promise for type 1 diabetes (T1D). Preclinical success for this approach has been demonstrated in vivo, however, clinical translation is still pending. Reasons explaining the slow progress to approve A
Externí odkaz:
https://doaj.org/article/d210fd360f95451ba276abc05d6bbaf6
Autor:
Johnna D Wesley, Susanne Pfeiffer, Darius Schneider, David Friedrich, Nikole Perdue, Birgit Sehested‐Hansen, William Hagopian, Matthias G vonHerrath
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 7, Pp n/a-n/a (2021)
Abstract Objectives The detection of a peripheral immune cell signature that specifically reflects autoimmunity in type 1 diabetes would enable the prediction and staging of disease on an individual basis. However, defining such a signature is techni
Externí odkaz:
https://doaj.org/article/84e8aa5527264108b268cc5823d0cff8
Autor:
Stephen C. Jennings MS, Kenneth M. Manning MS, Janet Prvu Bettger ScD, Katherine M. Hall PhD, Megan Pearson MA, Catalin Mateas BS, Brandon C. Briggs MS, Krisann K. Oursler MD, Erin Blanchard MS, Cathy C. Lee MD, Steven Castle MD, Willy M. Valencia MD, Leslie I. Katzel MD, Jamie Giffuni MA, Teresa Kopp MBA, PT, Michelle McDonald BA, OT, Rebekah Harris PT, DPT, Jonathan F. Bean MD, MPH, Katherine Althuis MS, Neil B. Alexander MD, Kalpana P. Padala MD, MS, Lauren M. Abbate MD, PhD, Toby Wellington MS, James Kostra MS, Kelly Allsup MS, Daniel E. Forman MD, Arti S. Tayade MD, Alan D. Wesley BA, Alice Holder PT, Miriam C. Morey PhD
Publikováno v:
Gerontology and Geriatric Medicine, Vol 6 (2020)
Exercise is critical for health maintenance in late life. The COVID-19 shelter in place and social distancing orders resulted in wide-scale interruptions of exercise therapies, placing older adults at risk for the consequences of decreased mobilizati
Externí odkaz:
https://doaj.org/article/c38b01ebae544e3384fab40ae3ac6198
Autor:
John Sidney, Jose Luis Vela, Dave Friedrich, Ravi Kolla, Matthias von Herrath, Johnna D. Wesley, Alessandro Sette
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Type 1 diabetes (T1D) is thought to be an autoimmune disease driven by anti-islet antigen responses and mediated by T-cells. Recent published data suggests that T-cell reactivity to modified peptides, effectively neoantigens, may
Externí odkaz:
https://doaj.org/article/3652a2db71974c839a66d26a3602d43e
Autor:
Laurence D Wesley, Michael J D Dobie
Publikováno v:
Proceedings of the Institution of Civil Engineers - Engineering History and Heritage. 175:145-152
The cone penetration test (CPT) was developed in the Netherlands in the early 1930s as a deep-sounding apparatus that measured cone resistance and was used to assess the distribution of alluvial soils and peat. It was developed further by increasing
Autor:
Matthias Bosman, Dustin N. Krüger, Kasper Favere, Callan D. Wesley, Cédric H. G. Neutel, Birgit Van Asbroeck, Owen R. Diebels, Bart Faes, Timen J. Schenk, Wim Martinet, Guido R. Y. De Meyer, Emeline M. Van Craenenbroeck, Pieter-Jan D. F. Guns
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12812 (2021)
Clinical and animal studies have demonstrated that chemotherapeutic doxorubicin (DOX) increases arterial stiffness, a predictor of cardiovascular risk. Despite consensus about DOX-impaired endothelium-dependent vasodilation as a contributing mechanis
Externí odkaz:
https://doaj.org/article/8ef902cdf43d4d1c86a08671e28649fc
Autor:
Cate Speake, Henry T. Bahnson, Johnna D. Wesley, Nikole Perdue, David Friedrich, Minh N. Pham, Erinn Lanxon-Cookson, William W. Kwok, Birgit Sehested Hansen, Matthias von Herrath, Carla J. Greenbaum
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Immune analytes have been widely tested in efforts to understand the heterogeneity of disease progression, risk, and therapeutic responses in type 1 diabetes (T1D). The future clinical utility of such analytes as biomarkers depends on their technical
Externí odkaz:
https://doaj.org/article/f9e809a44be54d9197a31771f3c2ac83
Publikováno v:
In Neuropsychologia 29 July 2016 88:74-82