Zobrazeno 1 - 10
of 157
pro vyhledávání: '"D. Walter Wray"'
Publikováno v:
Experimental Physiology, Vol 109, Iss 4, Pp 502-512 (2024)
Abstract Heart failure with preserved ejection fraction (HFpEF) accounts for over 50% of all heart failure cases nationwide and continues to rise in its prevalence. The complex, multi‐organ involvement of the HFpEF clinical syndrome requires clinic
Externí odkaz:
https://doaj.org/article/c7b29b819e70492b8dba65d83a4618f3
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Systemic sclerosis (SSc) is a rare, auto-immune disease with variably progressive fibrosis of the skin and internal organs, as well as vascular dysfunction. Recently, we demonstrated a decrement in exercising skeletal muscle blood flow and endotheliu
Externí odkaz:
https://doaj.org/article/1530f8fa6c884bd680ffedfcc3d30dda
Autor:
Caitlin C. Fermoyle, D. Taylor La Salle, Jeremy K. Alpenglow, Jesse C. Craig, Catherine L. Jarrett, Ryan M. Broxterman, Alec I. McKenzie, David E. Morgan, Nathaniel M. Birgenheier, D. Walter Wray, Russell S. Richardson, Joel D. Trinity
Publikováno v:
Journal of Applied Physiology. 134:1124-1134
Stimulation of α1-adrenergic receptors eliminated age-related differences in passive leg movement (PLM) by decreasing PLM-induced vasodilation in the young. Systemic β-blockade attenuated the central hemodynamic component of the PLM response in you
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857ce0f46b80e3813845d1f61cf0cad4
https://doi.org/10.1152/japplphysiol.00682.2022
https://doi.org/10.1152/japplphysiol.00682.2022
Autor:
Stephen M. Ratchford, Kanokwan Bunsawat, Jeremy K. Alpenglow, Jia Zhao, Josephine B. Wright, John J. Ryan, D. Walter Wray
Publikováno v:
Journal of Applied Physiology. 134:328-338
The current investigation has demonstrated that l-Cit administration may improve brachial artery endothelium-dependent vasodilation, upper and lower limb microvascular function, and physical capacity in patients with HFpEF, highlighting the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6647d1f771e35a36bf8c6fe92a43b303
https://doi.org/10.1152/japplphysiol.00445.2022
https://doi.org/10.1152/japplphysiol.00445.2022
Autor:
Kanokwan Bunsawat, Heather L. Clifton, Stephen M. Ratchford, Jennifer R. Vranish, Jeremy K. Alpenglow, Mark J. Haykowsky, Joel D. Trinity, John J. Ryan, Paul J. Fadel, D. Walter Wray
Publikováno v:
Journal of Applied Physiology.
Exercise intolerance is a well-described characteristic of heart failure with preserved ejection fraction (HFpEF), but whether disease-related changes in autonomic function contribute to impaired cardiovascular control during exercise is not well und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb631c780e0d17b8496b0b11eba44575
https://doi.org/10.1152/japplphysiol.00045.2023
https://doi.org/10.1152/japplphysiol.00045.2023
Autor:
Kanokwan Bunsawat, Seth Holwerda, Jeremy Alpenglow, Ryan Broxterman, Michael Francisco, Jesse Craig, Jarred Iacovelli, Joshua Weavil, Danilo Iannetta, Erin Inglis, Eric Tuday, Jonathan Harrison, Christy Ma, John Ryan, D. Walter Wray
Publikováno v:
Physiology. 38
Background: The arterial baroreflex (ABR) plays an important role in evoking appropriate cardiovascular adjustments in response to perturbations such as exercise. The ABR control of heart rate (HR) becomes attenuated with advancing age and in a varie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::520605aa592f01cc997edfc23649afe1
https://doi.org/10.1152/physiol.2023.38.s1.5731195
https://doi.org/10.1152/physiol.2023.38.s1.5731195
Autor:
Angela V, Bisconti, Ryan S, Garten, Ryan M, Broxterman, Catherine L, Jarrett, Soung Hun, Park, Katherine L, Shields, Heather L, Clifton, Stephen M, Ratchford, Van, Reese, Jia, Zhao, D Walter, Wray, Russell S, Richardson
Publikováno v:
J Appl Physiol (1985)
As a deficiency in tetrahydrobiopterin (BH(4)), a cofactor for endothelial nitric oxide synthase, has been implicated in the age-related decline in vascular function, this study aimed to determine the impact of acute BH(4) supplementation on flow-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7415255faba3c9cb7b44f50f254fbb4
https://pubmed.ncbi.nlm.nih.gov/35112931
https://pubmed.ncbi.nlm.nih.gov/35112931
Autor:
Stephen M. Ratchford, Joshua F. Lee, Kanokwan Bunsawat, Jeremy K. Alpenglow, Jia Zhao, Christy L. Ma, John J. Ryan, Lillian L. Khor, D. Walter Wray
Publikováno v:
J Appl Physiol (1985)
Obesity is now considered a primary comorbidity in heart failure with preserved ejection fraction (HFpEF) pathophysiology, mediated largely by systemic inflammation. Although there is accumulating evidence for a disease-related dysregulation of blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea022aeb8adefa7287fc7ebb4ff83b3
https://doi.org/10.1152/japplphysiol.00833.2021
https://doi.org/10.1152/japplphysiol.00833.2021
Autor:
Angela V. Bisconti, Ryan S. Garten, Ryan M. Broxterman, Catherine L. Jarrett, Soung Hun Park, Katherine L. Shields, Heather L. Clifton, Stephen M. Ratchford, Van Reese, Jia Zhao, D. Walter Wray, Russell S. Richardson
Publikováno v:
Journal of Applied Physiology. 132:773-784
Despite two different experimental approaches, acute BH4 supplementation did not affect vascular function in older adults, as measured by flow-mediated vasodilation. Plasma levels of both BH4 and BH2, the BH4 oxidized form, significantly increased af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc56c680f83566457bfea59011c17e1
https://doi.org/10.1152/japplphysiol.00711.2021
https://doi.org/10.1152/japplphysiol.00711.2021
Autor:
D. Walter Wray, Stephen M. Ratchford, Jeremy K. Alpenglow, H. Jonathan Groot, John J. Ryan, Joshua F. Lee, Russell S. Richardson, Michael A. Francisco, Kanokwan Bunsawat, J.N. Nativi, Zachary Barrett-O'Keefe
Publikováno v:
Hypertension
While there is emerging evidence of peripheral microvascular dysfunction in patients with heart failure with preserved ejection fraction that may be related to systemic inflammation and redox imbalance, disease-related changes in locomotor muscle mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da59625d2ebe16e9bb5ec863d2eb77c
https://doi.org/10.1161/hypertensionaha.121.17875
https://doi.org/10.1161/hypertensionaha.121.17875