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Autor:
D. Walliker
Publikováno v:
Parasitology Today. 7:232-235
The 'clonality' hypothesis proposed by Michel Tibayrenc and his colleagues(1) has stimulated a long-overdue debate on the genetic structure of populations of protozoan parasites. A critical aspect of the hypothesis is the role of a sexual phase in th
Autor:
D, Walliker, A P, Waters
Publikováno v:
Parassitologia. 41(1-3)
We provide a brief commentary on aspects of the analysis of the genetics and evolution of malaria parasites. Any attempt to understand the nature and manifestations of an infectious disease requires an understanding of the genetics of both pathogen a
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 93
Plasmodium falciparum parasites exist as genetically distinct haploid clones in infected people. In the Kilombero valley in south-east Tanzania, at least 85% of the inhabitants of Michenga village harbour more than one clone. Using 2 highly polymorph
Publikováno v:
Molecular and biochemical parasitology. 84(1)
Publikováno v:
The Journal of parasitology. 82(6)
Effectiveness of random amplified polymorphic DNA (RAPD), a technique using 1 10-base primer to amplify random segments of genomic DNA, and some of its possible uses were tested in the A + T-rich genome of Plasmodium falciparum. The best concentratio
Autor:
D, Wakelin, D, Walliker
Publikováno v:
Parasitology.
Autor:
D, Walliker, G, Beale
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 21
Publikováno v:
Journal of helminthology. 66(1)
Seven geographically varied isolates of Strongyloides ratti were cloned. Each clone was examined for the degree of homogonic development of the free-living generation and by enzyme electrophoresis. Considerable variation was found between the clones
Autor:
B, Fenton, D, Walliker
Publikováno v:
Sub-cellular biochemistry. 18