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Akademický článek

Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis

Autor: Chao Liang, Songlin Peng, Jie Li, Jun Lu, Daogang Guan, Feng Jiang, Cheng Lu, Fangfei Li, Xiaojuan He, Hailong Zhu, D. W. T. Au, Dazhi Yang, Bao-Ting Zhang, Aiping Lu, Ge Zhang

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

BMP promotes bone formation but its efficacy is limited in some patients. Here, the authors show that osteoporosis patients with a poor response to BMP have increased expression of Smurf1, which targets BMP effectors for degradation, and demonstrate

Externí odkaz: https://doaj.org/article/0b158da3ebda4212a171a0e9badbc8f5

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Expression profile of oestrogen receptors and oestrogen-related receptors is organ specific and sex dependent: the Japanese medaka Oryzias latipes model

Autor: N K M, Cheung, A C K, Cheung, R R, Ye, W, Ge, J P, Giesy, D W T, Au

Publikováno v: Journal of fish biology. 83(2)

Gene expression of all known subtypes of oestrogen receptor (ER) and oestrogen-related receptor (ERR) in multiple organs and both sexes of the Japanese medaka Oryzias latipes was profiled and systematically analysed. As revealed by statistical analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c41485630b86e666dd57f0b7ca1a535e
https://pubmed.ncbi.nlm.nih.gov/23902307

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