Zobrazeno 1 - 10
of 27
pro vyhledávání: '"D. W. Stacey"'
Autor:
Jyoti A. Harwalkar, D. W. Stacey, D. J. Stein, Joung H. Lee, Vidyodhaya Sundaram, Margaret Roudebush, M. Golubic
Publikováno v:
British Journal of Cancer
Meningiomas are common, mostly benign, tumours arising from leptomeningeal cells of the meninges, which frequently contain mutations in the neurofibromatosis type 2 (NF2) gene. In this study, we analysed a protein product of the neurofibromatosis typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d95c243e6c1521cb22396640a2004f
https://doi.org/10.1038/bjc.1997.456
https://doi.org/10.1038/bjc.1997.456
Publikováno v:
Molecular and Cellular Biology. 13:6799-6809
Morphological transformation of NIH 3T3 cells was observed following coexpression of a portion of the ras GTPase-activating protein (GAP) comprising the amino terminus (GAP-N) and a mutant of v-src (MDSRC) lacking the membrane-localizing sequence. Ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef1e1fdf82a1a71eda3e9a9c6c8a6aa
https://doi.org/10.1128/mcb.13.11.6799
https://doi.org/10.1128/mcb.13.11.6799
Publikováno v:
International journal of cancer. 75(2)
Twenty-one-day-old BALB/c mice were shaved on the back to synchronize hair growth. On day 30 or 31, when at least 90% of mice exhibited hair regrowth in the shaved area, 1,25(OH)2D3 was applied topically to the shaved area daily for 5 days. On the 6t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8851262bdd7b9b79ea8dd4b65aa808a7
https://pubmed.ncbi.nlm.nih.gov/9462723
https://pubmed.ncbi.nlm.nih.gov/9462723
Autor:
C M, Weyman, D W, Stacey
Publikováno v:
Anticancer research. 16(1)
An intact proliferative signalling pathway is essential to the growth of all normal cells, but is often not required by tumor cells. This fact was used to devise a protective chemotherapeutic protocol potentially applicable to all tissues. Four treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3cb1425c6aaed8d64c4331da257f53a
https://pubmed.ncbi.nlm.nih.gov/8615661
https://pubmed.ncbi.nlm.nih.gov/8615661
Publikováno v:
Oncogene. 9(12)
Directed endothelial cell (EC) movement is required for the development and repair of blood vessels and plays a critical role in angiogenic processes obligatory for large tumor formation. We now report that ras proteins have a critical role in regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7ac9fd8a4ef5bd161f7f8e1be3f5a12
https://pubmed.ncbi.nlm.nih.gov/7970712
https://pubmed.ncbi.nlm.nih.gov/7970712
Publikováno v:
Oncogene. 9(9)
E2F is a cellular transcription factor that is regulated during the cell cycle through interactions with the product of the retinoblastoma susceptibility gene (RB1) and the pRb-like p107 and p130 proteins. Analysis of mutations within both adenovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35bc0021ecebffd510a3ab0fa20f4fd7
https://pubmed.ncbi.nlm.nih.gov/8058324
https://pubmed.ncbi.nlm.nih.gov/8058324
Publikováno v:
Molecular and cellular biology. 13(11)
Morphological transformation of NIH 3T3 cells was observed following coexpression of a portion of the ras GTPase-activating protein (GAP) comprising the amino terminus (GAP-N) and a mutant of v-src (MDSRC) lacking the membrane-localizing sequence. Ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3eeba73d100fe477652a2cfc0d5e693
https://pubmed.ncbi.nlm.nih.gov/7692232
https://pubmed.ncbi.nlm.nih.gov/7692232
Publikováno v:
The Journal of biological chemistry. 268(28)
Transforming growth factor beta 1 (TGF beta 1) is a potent inhibitor of epithelial cell growth, although the mechanism of growth inhibition remains unknown. We report here a critical relationship between cellular p21ras activity and TGF beta 1 action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ef40d7b77b5ec7a61920225e396a02e
https://pubmed.ncbi.nlm.nih.gov/8407989
https://pubmed.ncbi.nlm.nih.gov/8407989
Autor:
Parvin Homayoun, D. W. Stacey
Publikováno v:
Biochemical and biophysical research communications. 195(1)
The intrinsic GTPase activity of cellular protein p21ras is strongly increased by cytosolic GTPase activating protein (GAP). The activity of this enzyme has been shown to be inhibited by arachidonic acid. We report here that this inhibition is antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5cefabe0e931089dc198b1bf5e14c3
https://pubmed.ncbi.nlm.nih.gov/8363595
https://pubmed.ncbi.nlm.nih.gov/8363595
Autor:
D. W. Stacey
Publikováno v:
GTPases in Biology I ISBN: 9783642782695
Proliferation is undoubtedly controlled by the flow of biochemical signals between various cellular molecules and classes of molecules, originating from an extracellular source and terminating at an as yet undefined intracellular target. In defining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58669311a9d64ae79cbdf8f76a0bf68
https://doi.org/10.1007/978-3-642-78267-1_20
https://doi.org/10.1007/978-3-642-78267-1_20
