Zobrazeno 1 - 10 of 24 pro vyhledávání: '"D. W. Hein"'
2
Elective lymph node dissection in stage I malignant melanoma
Autor: D. W. Hein, R. L. Moy
Publikováno v: Melanoma Research. 2:273-278
The role of elective lymph node dissection (ELND) in stage I melanoma has been a controversial issue for decades. Numerous studies have been conducted to try to establish the benefit of ELND versus wide local excision (WLE). The majority of these stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f350ca30441e308c2a51b52d1300a5
https://doi.org/10.1097/00008390-199211000-00008
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3
DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine
Autor: A J, Fretland, U S, Devanaboyina, N A, Nangju, M A, Leff, G H, Xiao, S J, Webb, M A, Doll, D W, Hein
Publikováno v: Journal of biochemical and molecular toxicology. 15(1)
N-acetyltransferases (EC 2.3.1.5) catalyze O-acetylation of heterocyclic amine carcinogens to DNA-reactive electrophiles that bind and mutate DNA. An acetylation polymorphism exists in humans and Syrian hamsters regulated by N-acetyltransferase-2 (NA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fd9beaa18ef71a96de1b8daa3cc03d4c
https://pubmed.ncbi.nlm.nih.gov/11170312
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4
Symposium overview: the role of genetic polymorphism and repair deficiencies in environmental disease
Autor: J E, Hulla, M S, Miller, J A, Taylor, D W, Hein, C E, Furlong, C J, Omiecinski, T A, Kunkel
Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 47(2)
A symposium of this title was presented at the 37th Annual Meeting of the Society of Toxicology held in Seattle, Washington during March of 1998. The symposium focused on heritable variations in metabolism, DNA replication, and DNA repair that may pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0cf2d752fd78c7c8d134fb92f6ea9af
https://pubmed.ncbi.nlm.nih.gov/10220849
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5
2-Aminofluorene-DNA adduct levels in tumor-target and nontarget organs of rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus
Autor: Y, Feng, W, Jiang, D W, Hein
Publikováno v: Toxicology and applied pharmacology. 141(1)
DNA adduct formation is an important initial event in chemical carcinogenesis. Metabolic activation and deactivation pathways are involved in aromatic amine carcinogenesis, and genetic polymorphism in the N-acetyltransferase 2 (NAT2) gene is associat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce417abc9acf1ac3964ea0106605d570
https://pubmed.ncbi.nlm.nih.gov/8917697
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6
Ambulantes Operieren gehört in die Praxis - Pro
Autor: D.-W. Hein
Publikováno v: Deutsche Gesellschaft für Chirurgie ISBN: 9783540583998
In der historischen Entwicklung ist ambulantes Operieren immer personengebunden gewesen. Die heutigen Organisationsformen des ambulanten Operierens in der Praxis des niedergelassenen Chirurgen werden dargestellt. Sechs wichtige Voraussetzungen bilden
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b448ae345545c6e99e0b332bfab1171
https://doi.org/10.1007/978-3-642-79242-7_328
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8
[Possibilities of therapy of hallux valgus et rigidus in a private hospital (Swanson great toe implant)]
Autor: D W, Hein
Publikováno v: Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress.
In 1983 we decided to use Swanson's great toe implants in selected cases after previous clinical examinations and X-ray tests, especially the stemmed or the stemmed hinge great toe implant based on Swanson/Weil and the Swanson silastic HP double stem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::925bb6b4990755034a673449b557e9e7
https://pubmed.ncbi.nlm.nih.gov/1793937
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9
Möglichkeiten der Therapie des Hallux valgus et rigidus in einem Belegkrankenhaus (Großzehimplantate nach Swanson)
Autor: D.-W. Hein
Publikováno v: Die Chirurgie und ihre Spezialgebiete Eine Symbiose ISBN: 9783540543350
Wir entschlossen uns 1983, in ausgewahlten Fallen nach vorheriger klinischer und rontgenologischer Untersuchung, Groszehimplantate nach Swanson zu verwenden und zwar das einstammige, das einstammige gewinkelte Groszehimplantat — modifiziert nach Sw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::535220946830f4016b68ca4e0ac87a71
https://doi.org/10.1007/978-3-642-95662-1_179
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10
Phase I/II dose-escalation trial of amonafide for treatment of advanced solid tumors: Genotyping to optimize dose based on polymorphic metabolism
Autor: D. M. Brown, N. Willcutt, D. W. Hein, F. A. Greco, D. S. Thompson, A. A. Meluch, H. A. Burris, Richard Stephen Schwartz, Suzanne F. Jones, J. G. Kuhn
Publikováno v: Journal of Clinical Oncology. 25:2503-2503
2503 Background: Amonafide (AMF), a synthetic imide derivative of naphthalic acid, is a topoisomerase II inhibitor and is subject to polymorphic metabolism based on acetylation genotype. AMF is extensively metabolized by N-acetyltransferase 2 (NAT2)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9b0701f21db9e8460288543d71a6105
https://doi.org/10.1200/jco.2007.25.18_suppl.2503
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