Zobrazeno 1 - 8 of 8 pro vyhledávání: '"D. W. Cope"'
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Loss of zolpidem efficacy in the hippocampus of mice with the GABAAreceptor γ2 F77I point mutation
Autor: Elli Leppä, Peer Wulff, Waltraud Ogris, Marco Capogna, Peter Somogyi, H. Hoeger, Esa R. Korpi, Anni-Maija Linden, William Wisden, Werner Sieghart, A. Oberto, C. Halbsguth, Theofanis Karayannis, D. W. Cope, Francesco Ferraguti
Publikováno v: Cope, D W, Halbsguth, C, Karayannis, T, Wulff, P, Ferraguti, F, Hoeger, H, Leppä, E, Linden, A-M, Oberto, A, Ogris, W, Korpi, E R, Sieghart, W, Somogyi, P, Wisden, W & Capogna, M 2005, ' Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation ', The European journal of neuroscience, vol. 21, no. 11, pp. 3002-16 . https://doi.org/10.1111/j.1460-9568.2005.04127.x
Europe PubMed Central
Zolpidem is a hypnotic benzodiazepine site agonist with some gamma-aminobutyric acid (GABA)(A) receptor subtype selectivity. Here, we have tested the effects of zolpidem on the hippocampus of gamma2 subunit (gamma2F77I) point mutant mice. Analysis of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5a0e4e690a4883f85a630b50b1ff98
https://doi.org/10.1111/j.1460-9568.2005.04127.x
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3
Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor γ2 subunit
Autor: A. Poeltl, Peter Somogyi, C. Halbsguth, M. I. Aller, Andrew N. J. McKenzie, Esa R. Korpi, Peer Wulff, Francesco Ferraguti, Helen E. Jolin, A. Oberto, Waltraud Ogris, Werner Sieghart, Marco Capogna, William Wisden, Erwin Sigel, D. W. Cope, H. Hoeger, A. Jones, Olga Vekovischeva, Saku T. Sinkkonen
Publikováno v: Cope, D W, Wulff, P, Oberto, A, Aller, M I, Capogna, M, Ferraguti, F, Halbsguth, C, Hoeger, H, Jolin, H E, Jones, A, McKenzie, A N J, Ogris, W, Poeltl, A, Sinkkonen, S T, Vekovischeva, O Y, Korpi, E R, Sieghart, W, Sigel, E, Somogyi, P & Wisden, W 2004, ' Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit ', Neuropharmacology, vol. 47, no. 1, pp. 17-34 . https://doi.org/10.1016/j.neuropharm.2004.03.007
Agonists of the allosteric benzodiazepine site of GABAA receptors bind at the interface of the alpha and gamma subunits. Here, we tested the in vivo contribution of the gamma2 subunit to the actions of zolpidem, an alpha1 subunit selective benzodiaze
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ac0f98f84fc830d43a86bf89689b9a
https://doi.org/10.1016/j.neuropharm.2004.03.007
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4
Cholecystokinin-immunopositive basket and Schaffer collateral-associated interneurones target different domains of pyramidal cells in the CA1 area of the rat hippocampus
Autor: D. W. Cope, László F. Márton, P M Cobden, Gianmaria Maccaferri, J.D.B Roberts, Peter Somogyi
Publikováno v: Neuroscience. 109:63-80
Two types of GABAergic interneurone are known to express cholecystokinin-related peptides in the isocortex: basket cells, which preferentially innervate the somata and proximal dendrites of pyramidal cells; and double bouquet cells, which innervate d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2712260add484ac4eafe7b31cc595e
https://doi.org/10.1016/s0306-4522(01)00440-7
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5
Ectopic expression of the GABA(A) receptor alpha6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition
Autor: A. Jones, Peter Somogyi, Istvan Mody, Verena Tretter, Thomas Klausberger, William Wisden, Rafael Luján, D. W. Cope, Birgit Hauer, Werner Sieghart, Esa R. Korpi, S. T. Sinkkonen
Publikováno v: Neuropharmacology. 43(4)
We generated transgenic (Thy1alpha6) mice in which the GABA(A) receptor alpha6 subunit, whose expression is usually confined to granule cells of cerebellum and cochlear nuclei, is ectopically expressed under the control of the pan-neuronal Thy-1.2 pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcebf58649c1f580239055d22ba2c3f9
https://pubmed.ncbi.nlm.nih.gov/12367600
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6
Affect and neutrality in physician behavior: a study of patients' values and satisfaction
Autor: D W Cope, L S Linn, Betty L. Chang, M R DiMatteo
Publikováno v: Journal of behavioral medicine. 8(4)
Physicians' emotional expressivity was contrasted with emotional neutrality in a study of consumers' preferences regarding physician behavior in the medical encounter. Two hundred twenty-seven health-science students completed instruments designed to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa1e944bbfe3eee726db0f871b8de80
https://pubmed.ncbi.nlm.nih.gov/4093975
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8
The Use of Graphic Input and Output Devices Attached to a Small Computer for Planning Radiotherapy Treatment
Autor: J. Milan, R. E. Bentley, D. W. Cope
Publikováno v: Computer Graphics in Medical Research and Hospital Administration ISBN: 9781461586500
The planning of treatment by radiation therapy is essentially a graphical problem. The object is to arrange X-ray fields in such a manner that regions of diseased tissue receive a high uniform dose while minimising the dose to certain critical organs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::319a6669e90baaddb9bdd0095ad054d8
https://doi.org/10.1007/978-1-4615-8648-7_3
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