Zobrazeno 1 - 10
of 10
pro vyhledávání: '"D. W. A. Bourne"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:2392-2397
The in vitro erythromycin-binding properties of bovine alpha-1-acid glycoprotein (AAG) and albumin were studied by using equilibrium dialysis. In addition, the proportions of free erythromycin in bovine serum and tissue chamber fluid before and 4 day
Autor:
V V, Dimas, V V, Dimasc, M D, Taylor, C B, Cunnyngham, E D, Overholt, D W A, Bourne, J R, Stanely, A, Sheikh, R, Wolf, B, Valentine, K E, Ward
Publikováno v:
Pediatric cardiology. 26(6)
The objective of this study was to characterize the transfer of flecainide across the placenta and determine the fetal: maternal ratio of flecainide in the gravid baboon. Flecainide acetate has been especially successful for the treatment of fetal su
Publikováno v:
European Journal of Clinical Pharmacology. 27:441-446
The pharmacokinetics of canrenone and 'total metabolites' after base hydrolysis was studied in eight young volunteers following single and multiple dose oral administration of spironolactone. The plasma levels of canrenone and 'total metabolites' wer
Publikováno v:
Acta Radiologica: Oncology. 20:365-371
Complexes of carrier-gallium and indium were administered to normal rats and rats with tumors 2 to 6 hours after an injection of carrier-free 67Ga citrate in order to determine their effect on the distribution of 67Ga. Both Ga and In rapidly and sign
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 7(4)
The pharmacokinetics of cefotaxime and probenecid, given by intravenous injection, were determined in six Merino ewes which had been subjected to a 75% reduction in renal mass. These results were compared with results previously determined in sheep w
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 19(7)
1. The pharmacokinetics and protein binding of cefotaxime and desacetylcefotaxime were studied in rat. 2. After i.v. dosing of cefotaxime (100 mg/kg) the concentration-time profiles of cefotaxime and its metabolite desacetylcefotaxime followed biphas
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 12(3)
The purpose of this study was to characterize the pharmacokinetics of a subcutaneously implanted tissue-chamber model. Thermoplastic tissue chambers were implanted in the paralumbar fossae of six steers. Starting 30 days after implantation, the distr
Publikováno v:
European journal of clinical pharmacology. 27(4)
Plasma levels of canrenone and ‘total metabolites’ after base hydrolysis were compared in young and elderly subjects following single and multiple doses of spironolactone. After the initial dose on Day 1, plasma levels of canrenone and ‘total m
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 19(8)
1. The pharmacokinetic profile and protein binding parameters of ceftriaxone were determined in rat, and compared with those of cefotaxime. 2. Plasma concentration-time curves of ceftriaxone and cefotaxime (single i.v. bolus; 100 mg/kg each) were des
Autor:
G. D. Koritz, D. W. A. Bourne
Publikováno v:
Veterinary Research Communications. 7:311-312