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Comparative analysis of regulatory information and circuits across distant species

Autor: Pouya Kheradpour, Yi-Chieh Wu, Michael Snyder, Steven E. Brenner, Trupti Kawli, Mark Gerstein, Lixia Jiang, Robert Terrell, Anshul Kundaje, Wei Niu, Matthew Slattery, Manolis Kellis, Peter J. Good, LaDeana W. Hillier, Robert H. Waterston, Koon-Kiu Yan, Haiyan Huang, E. Jay Rehm, Carlos L. Araya, Philip Cayting, J. Janette, Jingyi Jessica Li, Chao Cheng, Elise A. Feingold, Alan P. Boyle, Michael J. Pazin, Peter Weisdepp, Joel Rozowsky, Lijia Ma, Peter J. Bickel, Dan Xie, D. Vafeados, Kathryn E. Gardner, Kevin P. White, Valerie Reinke, Dionna M. Kasper, Cathleen M. Brdlik, Daifeng Wang, Yong Cheng, Rebecca Spokony

Publikováno v: Boyle, AP; Araya, CL; Brdlik, C; Cayting, P; Cheng, C; Cheng, Y; et al.(2014). Comparative analysis of regulatory information and circuits across distant species. Nature, 512(7515), 453-456. doi: 10.1038/nature13668. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1rj5c5wg
Nature, vol 512, iss 7515
PMC
Nature

Despite the large evolutionary distances between metazoan species, they can show remarkable commonalities in their biology, and this has helped to establish fly and worm as model organisms for human biology. Although studies of individual elements an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ebcdf1f6bbfde561fe5c999cb36ed
https://doi.org/10.1038/nature13668

Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project

Autor: L. Dick, Mark S. Guyer, D. Mecenas, William C. Spencer, Ming Sin Cheung, Sebastian D. Mackowiak, Tao Liu, A. Vielle, Abby F. Dernburg, Mitzi Morris, Bradley I. Arshinoff, Sheldon J. McKay, Amber Leahey, Thea A. Egelhofer, Lukas Habegger, Michael Snyder, Teruaki Takasaki, Roger P. Alexander, Stuart K. Kim, Ashish Agarwal, Ting Han, A. Leo Iniguez, Eric L. Van Nostrand, Gos Micklem, S. Taing, Ekta Khurana, Joel Rozowsky, Beijing Wu, Steven Henikoff, Adrian Carr, Philip Green, Angie S. Hinrichs, A. Muroyama, Jason D. Lieb, Paul Lloyd, Yaniv Lubling, P. Scheid, Kevin Y. Yip, Stefan R. Henz, Chao Cheng, Jiang Du, Mei Zhong, P. Alves, Elicia Preston, Zhi John Lu, Vishal Khivansara, Robert H. Waterston, J. Janette, C. Slightam, Frank J. Slack, David M. Miller, Eo Stinson, Nikolaus Rajewsky, Eran Segal, Jing Leng, Tony Hyman, R. Robilotto, C. Shou, Gunnar Rätsch, Eric C. Lai, Mihail Sarov, X. Shirley Liu, Isabel J. Latorre, A. Chateigner, Francois Gullier, Raymond K. Auerbach, W. James Kent, Sergio Contrino, Jeremy Brouillet, Lincoln Stein, T. Phippen, Andrea Sboner, Marco Mangone, Georg Zeller, Hoang Pham, Mark Gerstein, Michael J. MacCoss, Siew Loon Ooi, Cathleen M. Brdlik, D. Vafeados, Nicole L. Washington, Andreas Rechtsteiner, Peter J. Good, Susan Strome, Galt P. Barber, Kristin C. Gunsalus, John I. Murray, Valerie Reinke, Luke Dannenberg, Masaomi Kato, M. Jensen, X. Feng, John Kim, Kahn Rhrissorrakrai, H. Holster, Kohta Ikegami, Christina M. Whittle, M. Gutwein, Rachel Lyne, Wei Niu, Richard J.H. Smith, LaDeana W. Hillier, P. Kolasinska-Zwierz, Heidi Rosenbaum, Andréa C. Dosé, Xingliang Zhou, Marc D. Perry, Rajkumar Sasidharan, Rebecca F. Lowdon, Arshad Desai, Z. Zha, J. Brennan, Guilin Wang, P. Ruzanov, Brent Ewing, Gennifer E. Merrihew, Kim Rutherford, Reto Gassmann, Elise A. Feingold, Fabio Piano, Julie Ahringer, E. Kephart, Lucas Lochovsky, Sevinc Ercan, Suzanna E. Lewis, Ksenia Voronina, Koon-Kiu Yan, Jorja G. Henikoff, Hyunjin Shin, Hiram Clawson, Ghia Euskirchen

Publikováno v: Science. 330:1775-1787

From Genome to Regulatory Networks For biologists, having a genome in hand is only the beginning—much more investigation is still needed to characterize how the genome is used to help to produce a functional organism (see the Perspective by Blaxter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af1c9379c54f3982c93a77444265918c
https://doi.org/10.1126/science.1196914

Multidimensional regulation of gene expression in the C. elegans embryo

Autor: Thomas J. Boyle, D. Vafeados, Elicia Preston, John I. Murray, Max E. Boeck, Zhongying Zhao, Peter Weisdepp, Zhirong Bao, Robert H. Waterston, Barbara Mericle

Publikováno v: Genome research. 22(7)

How cells adopt different expression patterns is a fundamental question of developmental biology. We quantitatively measured reporter expression of 127 genes, primarily transcription factors, in every cell and with high temporal resolution in C. eleg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da4d8e694b17a9698504f1402ddaee7
https://pubmed.ncbi.nlm.nih.gov/22508763