Zobrazeno 1 - 10
of 17
pro vyhledávání: '"D. Vaessen"'
Autor:
Joost C. de Vries, Maaike K. van Gelder, Anneke S. Monninkhof, Sabbir Ahmed, Diënty H. M. Hazenbrink, Tri Q. Nguyen, Gèrard A. P. de Kort, Evert-Jan P. A. Vonken, Koen R. D. Vaessen, Jaap A. Joles, Marianne C. Verhaar, Karin G. F. Gerritsen
Publikováno v:
Toxins, Vol 14, Iss 9, p 635 (2022)
With increasing interest in home dialysis, there is a need for a translational uremic large animal model to evaluate technical innovations in peritoneal dialysis (PD). To this end, we developed a porcine model with kidney failure. Stable chronic kidn
Externí odkaz:
https://doaj.org/article/aa5fadff8d85457a9da6eea6c7408896
Autor:
Maaike K. van Gelder, Jasper Stevens, Tobias T. Pieters, Koen R. D. Vaessen, Jaap A. Joles, Marianne C. Verhaar, Karin G. F. Gerritsen
Publikováno v:
Biology, Vol 10, Iss 6, p 461 (2021)
The preclinical evaluation of novel therapies for chronic kidney disease requires a simple method for the assessment of kidney function in a uremic large animal model. An intravenous bolus of iohexol was administered to goats (13 measurements in n =
Externí odkaz:
https://doaj.org/article/38f7e1745b584b3a8fc55b0e80e49aa8
Autor:
Maaike K. van Gelder, Joost C. de Vries, Sabbir Ahmed, Anneke S. Monninkhof, Gérard A. P. de Kort, Evert-Jan P. A. Vonken, Diënty H. M. Hazenbrink, Koen R. D. Vaessen, Tri Q. Nguyen, Marianne C. Verhaar, Jaap A. Joles, Karin G. F. Gerritsen
Publikováno v:
Biology, Vol 10, Iss 4, p 292 (2021)
A large animal model of (end-stage) kidney disease (ESKD) is needed for the preclinical testing of novel renal replacement therapies. This study aimed to create stable uremia via subtotal renal artery embolization in goats and induce a temporary furt
Externí odkaz:
https://doaj.org/article/d15d18d703ad47018f1cf55836d37dd7
Autor:
de Vries, Joost, van Gelder, Maaike K., S Monninkhof, Anneke, Ahmed, Sabbir, Hazenbrink, Diënty, Nguyen, Tri Q, Gèrard A P de Kort, Gèrard, P A Vonken, Evert-Jan, Koen R D Vaessen, Koen, Joles, Jaap A., Verhaar, Marianne C., Gerritsen, Karin G.F., Afd Pharmacology, Pharmacology, Pharmaceutics
Publikováno v:
Toxins; Volume 14; Issue 9; Pages: 635
Toxins, 14(9). MDPI AG
Toxins, 14(9). MDPI AG
With increasing interest in home dialysis, there is a need for a translational uremic large animal model to evaluate technical innovations in peritoneal dialysis (PD). To this end, we developed a porcine model with kidney failure. Stable chronic kidn
Autor:
Simone M. J. de Jong, Sylvia Dekker, Serena Buscone, Merle M. Krebber, Eva Brauchle, Emily B. Lurier, Koen R D Vaessen, Renee Duijvelshoff, Daniel A Carvajal-Berrio, Suzanne E Koch, Valentina Bonito, Carlijn V. C. Bouten, Patricia Y. W. Dankers, Anthal I.P.M. Smits, Marianne C. Verhaar, Tristan Mes, Katja Schenke-Layland, Anton W. Bosman, Julia Marzi
Publikováno v:
Advanced Healthcare Materials, 10(21):e2101103. Wiley
Two of the greatest challenges for successful application of small-diameter in situ tissue-engineered vascular grafts are 1) preventing thrombus formation and 2) harnessing the inflammatory response to the graft to guide functional tissue regeneratio
Autor:
Eva L van Donkelaar, Koen R D Vaessen, Jodi L Pawluski, Annerieke S Sierksma, Arjan Blokland, Ramón Cañete, Harry W M Steinbusch
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e106960 (2014)
Chronic stress or long-term administration of glucocorticoids disrupts the hypothalamus-pituitary-adrenal system leading to continuous high levels of glucocorticoids and insulin resistance (IR). This pre-diabetic state can eventually develop into typ
Externí odkaz:
https://doaj.org/article/79396bb81b664f64b2ad19b62bea12a0
Autor:
Karin G.F. Gerritsen, Jasper Stevens, Tobias T Pieters, Maaike K. van Gelder, Jaap A. Joles, Marianne C. Verhaar, Koen R D Vaessen
Publikováno v:
Biology
Volume 10
Issue 6
Biology, Vol 10, Iss 461, p 461 (2021)
Biology, 10(6):461. MDPI AG
Volume 10
Issue 6
Biology, Vol 10, Iss 461, p 461 (2021)
Biology, 10(6):461. MDPI AG
The preclinical evaluation of novel therapies for chronic kidney disease requires a simple method for the assessment of kidney function in a uremic large animal model. An intravenous bolus of iohexol was administered to goats (13 measurements in n =
Autor:
Saskia Redegeld, Ahmet Kinaci, Koen R D Vaessen, Tristan P.C. van Doormaal, Albert van der Zwan
Publikováno v:
Laboratory animals. 55(5)
A large craniotomy survival porcine model is useful for scientific research. The surgical approaches and complications of craniotomies in pigs have not been published before. This study describes how large craniotomies were performed in 46 pigs and h
Autor:
Sabbir Ahmed, Karin G.F. Gerritsen, Anneke S Monninkhof, Tri Q. Nguyen, Gerard A. P. de Kort, Maaike K. van Gelder, Koen R D Vaessen, Diënty H M Hazenbrink, Joost C de Vries, Evert-Jan Vonken, Jaap A. Joles, Marianne C. Verhaar
Publikováno v:
Biology
Volume 10
Issue 4
Biology, Vol 10, Iss 292, p 292 (2021)
Volume 10
Issue 4
Biology, Vol 10, Iss 292, p 292 (2021)
Simple Summary To improve the treatment of patients with kidney disease, new renal replacement therapies are being developed. Prior to their use in humans with end-stage kidney disease (ESKD), these therapies need to be tested in animals with kidney
Autor:
M.M. Moerman, Ingeborg M. Kooter, Dennis K. Ninaber, D. Vaessen, Pieter S. Hiemstra, V. Clarijs, Maria C. Zarcone, Marcel J. Alblas, Evert Duistermaat, A. van Schadewijk
Publikováno v:
Toxicology in Vitro, 48, 221-231
Harmful effects of diesel emissions can be investigated via exposures of human epithelial cells, but most of previous studies have largely focused on the use of diesel particles or emission sources that are poorly representative of engines used in cu