Zobrazeno 1 - 10
of 26
pro vyhledávání: '"D. V. Pyshnyi"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 27, Iss 7 (2023)
To date, many derivatives and analogs of nucleic acids (NAs) have been developed. Some of them have found uses in scientific research and biomedical applications. Their effective use is based on the data about their properties. Some of the most impor
Externí odkaz:
https://doaj.org/article/6d2ca25d2f9b458e9dc3d32bd7a58bca
Autor:
G. Y. Shevelev, D. V. Pyshnyi
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 22, Iss 5, Pp 498-506 (2018)
Synthetic biology is a rapidly developing field aimed at engineering of biological systems with predictable properties. Synthetic biology accumulates the achievements of modern biological sciences, programming and computational modeling as well as
Externí odkaz:
https://doaj.org/article/f3cd68c62dcb4dd48c838aa0af5036e3
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:937-948
Autor:
N. B. Asanbaeva, A. A. Sukhanov, A. A. Diveikina, O. Y. Rogozhnikova, D. V. Trukhin, V. M. Tormyshev, A. S. Chubarov, A. G. Maryasov, A. M. Genaev, A. V. Shernyukov, G. E. Salnikov, A. A. Lomzov, D. V. Pyshnyi, E. G. Bagryanskaya
Publikováno v:
Physical Chemistry Chemical Physics. 24:5982-6001
The distance measurement by W-band 19F ENDOR for pairs of TAM - 19F, and study the process of a thiol exchange.
Publikováno v:
Molecular Biology. 55:927-940
Abstract The development of approaches for predictive calculation of hybridization properties of various nucleic acid (NA) derivatives is the basis for the rational design of the NA-based constructs. Modern advances in computer modeling methods provi
Autor:
Alexander A. Lomzov, T. D. Zharkov, Maxim S. Kupryushkin, Svetlana N. Khodyreva, Ekaterina S Ilina, A. S. Kochetkova, M. M. Akhmetova, Olga I. Lavrik, D. V. Pyshnyi, Oleg V. Markov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:719-733
In this work, representatives of the class of triazinylamidophosphate oligonucleotide derivatives were obtained for the first time. A scheme for the introduction of a modified unit on a solid-phase support during the oxidation step with highly reacti
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:681-690
Abstract We have studied the antimicrobial and hemolytic activity of synthetic antimicrobial peptides (SAMPs), i.e., Arg9Phe2 (P1-Arg), Lys9Phe2 (P2-Lys), and His9Phe2 (P3-His), which have a “linear” type of amphipathicity and contain the cationi
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:380-389
Novel representatives of phosphoryl guanidine oligonucleotide derivatives were prepared in this study. A synthetic scheme has been proposed and implemented suitable for the preparation of a wide range of diaminocarbenium azides starting from various
Problems of the Synthesis of Oligonucleotide Derivatives in the Realization of the Anchimeric Effect
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:505-513
It has been found that the presence of a free OH group at the 3'-terminal residue of the substituted ethylene glycol fragment in a phosphoryl guanidine oligodeoxyribonucleotide derivative is a factor that determines the instability of the structure o
Autor:
Inna A. Pyshnaya, E. V. Dmitrienko, A. V. Poryvaeva, Maxim S. Kupryushkin, B. I. Fomin, Olga V. Naumova, D. V. Pyshnyi
Publikováno v:
Optoelectronics, Instrumentation and Data Processing. 57:44-50
The analysis of nucleic acids remains to be a topical trend in the development of medical diagnostics. Contemporary ultrasensitive diagnostic systems provide the conversion of a specific interaction into a hardwarely-detectable signal in the course o