Zobrazeno 1 - 10
of 46
pro vyhledávání: '"D. V. Faller"'
Autor:
S. P. Perrine, D. V. Faller
Publikováno v:
Experientia. 49:133-137
The inherited beta-hemoglobinopathies (sickle cell disease and beta thalassemia) are the result of a mutation in the adult (beta) globin gene. The fetal globin chain, encoded by the gamma globin genes, can substitute for the mutated or defective beta
Publikováno v:
The Journal of Immunology. 146:2417-2425
The mechanisms whereby RNA leukemia viruses cause T lymphocyte leukemias or lymphomas after a long latent period are not understood. We report here that infection of human T lymphocyte lines with a murine leukemia virus results in up-regulation of a
Publikováno v:
Transplant infectious disease : an official journal of the Transplantation Society. 3(3)
Lymphoproliferative disorders associated with the Epstein-Barr virus (EBV) include non-Hodgkin's lymphoma, Hodgkin's lymphoma, and "post-transplant lymphoproliferative disorders" (PTLD), which occur with immunosuppression after marrow and organ trans
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 12(6)
Oncogenic Ras induces cells to undergo apoptosis after inhibition of protein kinase C (PKC) activity. The integration of differential signaling pathways is required for full execution of apoptosis. In this study, we used Jurkat as well as Fas/FADD-de
Publikováno v:
Blood. 92(8)
The mechanisms by which pharmacologic agents stimulate gamma-globin gene expression in beta-globin disorders has not been fully established at the molecular level. In studies described here, nucleated erythroblasts were isolated from patients with be
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(6)
When treated with millimolar concentrations of butyrate, many cell types undergo growth arrest in the G1 phase of the cell cycle. However, the molecular basis of butyrate-induced G1 arrest has not been elucidated. We have investigated the molecular m
Publikováno v:
Journal of cellular physiology. 172(2)
Moloney murine leukemia virus (Mo-MuLV) is a thymotropic and leukemogenic retrovirus which causes T lymphomas. Recently, Mo-MuLV has been shown to trans-activate cellular genes. Monocyte chemoattractant protein-1 (MCP-1) is a chemokine which can prom
Autor:
R L, Comenzo, E, Vosburgh, R W, Simms, P, Bergethon, D, Sarnacki, K, Finn, S, Dubrey, D V, Faller, D G, Wright, R H, Falk, M, Skinner
Publikováno v:
Blood. 88(7)
The morbidity and lethality of AL amyloidosis is caused by the deposition of lg light chains as fibrillar amyloid protein in vital organs, disrupting their function, and not by the generally low burden of clonal plasma cells that produce the paraprot
Autor:
S J, Mentzer, J, Longtine, J, Fingeroth, J J, Reilly, M M, DeCamp, W, O'Donnell, S J, Swanson, D V, Faller, D J, Sugarbaker
Publikováno v:
Transplantation. 61(12)
Posttransplant lymphoproliferative disorders (PTLD) are EBV-associated lymphoid neoplasms that are caused by the uncontrolled growth of EBV-infected B lymphocytes. The clinical presentation of PTLD can range from benign polygonal lymphoproliferative
Autor:
M W, Phelan, D V, Faller
Publikováno v:
Journal of cellular physiology. 167(3)
Endothelial cell-generated nitric oxide (NO) accounts in large part for the labile vasodilator termed endothelium-derived relaxing factor. Two distinct types of NO synthase exist: a "constitutive' type (cNOS), found in endothelial cells, and an "indu