Zobrazeno 1 - 10
of 178
pro vyhledávání: '"D. Tuscano"'
Autor:
Okonkwo, Amaka1, Njeze, Ngozi Rosemary2, Onyekwelu, Kenechukwu Chibuike1 kenechukwu.onyekwelu@unn.edu.ng, Okorie, Chigozie Peace1, Ejiofor, Nonso Collins1, Ikekpeazu, Joy Ebele1
Publikováno v:
Jordan Journal of Biological Sciences. Sep2024, Vol. 17 Issue 3, p555-560. 6p.
Autor:
Annalisa Sala, Giampaolo Primofiore, Ettore Novellino, Karl-Norbert Klotz, Concettina La Motta, Antonio Da Settimo, Giovanni Greco, Federico Da Settimo, Maria Letizia Trincavelli, Sabrina Taliani, D. Tuscano, Claudia Martini, Antonio Lavecchia, Manuela Iadanza, B Cosimelli, Maria Grazia Rimoli, Marina Ehlardo
Publikováno v:
Journal of Medicinal Chemistry. 48:8253-8260
The Cambridge Structural Database (CSD) was searched through two 3D queries based on substructures shared by well-known antagonists at the A1 and A3 adenosine receptors (ARs). Among the resulting 557 hits found in the CSD, we selected five compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bb102b5a29de44830119c66640e88e
https://doi.org/10.1021/jm050792d
https://doi.org/10.1021/jm050792d
Autor:
Giuseppe Sancesario, D. Tuscano, Giorgio Bernardi, Nadia D'Ambrosi, Susanna Amadio, Cinzia Volonté, Claudia Martini, Maria Letizia Trincavelli
Publikováno v:
Neurochemistry international 47 (2005): 334–342. doi:10.1016/j.neuint.2005.05.008
info:cnr-pdr/source/autori:Amadio S.1, D'Ambrosi N.2, Trincavelli M.L.3, Tuscano D.4, Sancesario G.5, Bernardi G.6, Martini C.7, Volontè C.8/titolo:Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons./doi:10.1016%2Fj.neuint.2005.05.008/rivista:Neurochemistry international/anno:2005/pagina_da:334/pagina_a:342/intervallo_pagine:334–342/volume:47
info:cnr-pdr/source/autori:Amadio S.1, D'Ambrosi N.2, Trincavelli M.L.3, Tuscano D.4, Sancesario G.5, Bernardi G.6, Martini C.7, Volontè C.8/titolo:Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons./doi:10.1016%2Fj.neuint.2005.05.008/rivista:Neurochemistry international/anno:2005/pagina_da:334/pagina_a:342/intervallo_pagine:334–342/volume:47
Extracellular ATP and P2 receptors may play a crucial role in the neurodegeneration of the CNS. Here, we investigated in neuronal cerebellar granule cultures the biological effect of the quite stable P2 receptor agonist ATPgammaS and compare it to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62dfa31b75145e0b4b1597999fb8d74
https://doi.org/10.1016/j.neuint.2005.05.008
https://doi.org/10.1016/j.neuint.2005.05.008
Autor:
Alessia Mazzola, Nico Mitro, Maria Letizia Trincavelli, M Marroni, D. Tuscano, Claudia Martini, Stefania Ceruti, Maria P. Abbracchio
Publikováno v:
Journal of Neurochemistry. 91:1180-1190
Low-affinity A2B adenosine receptors (A2B ARs), which are expressed in astrocytes, are mainly activated during brain hypoxia and ischaemia, when large amounts of adenosine are released. Cytokines, which are also produced at high levels under these co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284970d7dcb15b9ac57f5b69ca0e865d
https://doi.org/10.1111/j.1471-4159.2004.02793.x
https://doi.org/10.1111/j.1471-4159.2004.02793.x
Autor:
D. Tuscano, A Lenzi
Publikováno v:
International Journal of Pharmaceutical Medicine. 18:139-148
At present, there are no really efficacious tools available to counteract cognitive deficits in patients with schizophrenia: even though new atypical antipsychotic drugs represent an advance compared with typical antipsychotic drugs, the results obta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b22a76f6a23caaee27ba9a894710625
https://doi.org/10.2165/00124363-200418030-00002
https://doi.org/10.2165/00124363-200418030-00002
Autor:
Concettina La Motta, Federico Da Settimo, Maria Letizia Trincavelli, Karl-Norbert Klotz, Giampaolo Primofiore, Claudia Martini, Barbara Cosimelli, Antonio Lavecchia, D. Tuscano, Sabrina Taliani, Giovanni Greco, Manuela Iadanza, Ettore Novellino
Publikováno v:
Drug Development Research. 63:1-7
3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-ones (ATBIs) 1 and N-alkyl and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) 2, recently reported by us as two novel classes of selective A1 adenosine receptor (A1AR) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefa196d5034ba792c022a2de65c8534
https://doi.org/10.1002/ddr.10366
https://doi.org/10.1002/ddr.10366
Autor:
F. Cattabeni, Vittorio Gremigni, D. Tuscano, Claudia Martini, Stefania Ceruti, Alessandra Falleni, M Marroni, Maria Letizia Trincavelli, Maria P. Abbracchio, Kenneth A. Jacobson
Publikováno v:
Molecular Pharmacology. 62:1373-1384
A(3) adenosine receptor activation has been previously demonstrated to result in both neuroprotective and neurodegenerative effects, depending upon specific pathophysiological conditions. This dual effect may depend on receptor regulation mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fa234b1b0d72f463c136e5d51ea790
https://doi.org/10.1124/mol.62.6.1373
https://doi.org/10.1124/mol.62.6.1373
Autor:
Maria Cristina Bianchi, Elisa Cerrai, Antonio Lucacchini, M. Catena, Giovanni B. Cassano, Antonio Ciapparelli, Liliana Dell'Osso, Letizia Novelli, Claudia Martini, Lucioni Alessio, Maria Letizia Trincavelli, D. Tuscano
Publikováno v:
Journal of psychiatric research. 40(1)
Antipsychotic drugs, potent dopamine receptor antagonists, are commonly used in the treatment of psychotic and affective illness. The discovery of antagonistic interactions between A2A adenosine receptors (ARs) and D2 dopamine receptors (DRs) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3e03c4a79226d0c705b471610ccec9
https://pubmed.ncbi.nlm.nih.gov/16431220
https://pubmed.ncbi.nlm.nih.gov/16431220
Serotonin-mediated cyclic AMP inhibitory pathway in platelets of patients affected by panic disorder
Autor:
Liliana Dell'Osso, Claudia Martini, Claudia Carmassi, Marina Montali, D. Tuscano, Lionella Palego, Antonio Ciapparelli, Antonio Lucacchini, Maria Letizia Trincavelli, Giovanni B. Cassano, Simone Sbrana
Cyclic adenosine monophosphate (cAMP) pathway abnormalities have been suggested to be involved in anxiety disorders including panic (PD). The present study sought at investigating the downstream inhibitory adenylyl cyclase (AC) pathway activated by 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3674e3fea7649c009117db11eecb18fe
http://hdl.handle.net/11568/204394
http://hdl.handle.net/11568/204394
