Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D. Thomas Dickey"'
Autor:
D. Thomas Dickey, Robert M. Strongin, Yu Hsuan Chu, Martha Sibrian-Vazquez, Qi Wang, Martina Ralle, Peter S. Steyger, Amanda R. Phillips, Jorge O. Escobedo
Publikováno v:
Molecular Pharmaceutics. 13:2677-2682
Cisplatin is widely used to treat a variety of cancers. However, ototoxicity and nephrotoxicity remain serious side effects of cisplatin-based chemotherapy. In order to inform the study of cisplatin’s off-target effects, a new drug-fluorophore conj
Autor:
Diane Palmieri, Quentin Smith, D. Thomas Dickey, Nancy D. Doolittle, Gregory A. Christoforidis, Bradley H Pollock, Edward A. Neuwelt, Kathleen C.M. Campbell, Darryl R. Peterson, David M. Peereboom, Penelope Brock, Carole Soussain, Rose Marie Tyson, Leslie L. Muldoon, Brian P. O'Neill, Walter A. Hall
Publikováno v:
Journal of Neuro-Oncology. 81:81-91
Although knowledge of molecular biology and cellular physiology has advanced at a rapid pace, much remains to be learned about delivering chemotherapy and antibodies across the blood–brain barrier (BBB) for the diagnosis and treatment of central ne
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 314:1052-1058
Cisplatin (CDDP) is a common, highly toxic chemotherapeutic agent. This study investigates chemoprotective effects of N-acetylcysteine (NAC) and sodium thiosulfate (STS) on in vitro and in vivo CDDP toxicities. For ototoxicity studies, CDDP (6 mg/kg)
Autor:
Edward A. Neuwelt, Brian W. Blakley, James I. Cohen, Leslie L. Muldoon, Kathleen C. M. Campbell, D. Thomas Dickey, Nancy D. Doolittle
Publikováno v:
The Laryngoscope. 112:1997-2001
Objectives To summarize the findings relevant to otolaryngology from the annual meeting of the Blood–Brain Barrier Disruption Consortium in Gleneden Beach, Oregon, March 10, 2001. Study Design Summaries are provided by the speakers, as well as rela
Autor:
Kenneth E. Bartels, Sean Heaton, D. Thomas Dickey, Robert L. Adams, Wei R. Chen, Robert E. Nordquist
Publikováno v:
Cancer Letters. 88:15-19
A diode laser was used to irradiate tumor tissue, with indocyanine green as the chromophore. The 808-nm wavelength radiation falls within the absorption peak of the chromophore (about 780 nm). The preliminary results in this report revealed clear and
Autor:
Dale F. Kraemer, Leslie L. Muldoon, Edward A. Neuwelt, Darryl R. Peterson, Nancy D. Doolittle, D. Thomas Dickey
Publikováno v:
Cancer chemotherapy and pharmacology. 62(2)
Dosing and route of administration of N-acetylcysteine (NAC) for protection against cisplatin (CDDP) nephrotoxicity was investigated in rats. Two models of toxicity were tested: a single high dose of CDDP (10 mg/kg intraperitoneally (IP)), and multip
Publikováno v:
Hearing research. 193(1-2)
Cisplatin (CDDP) is a widely used chemotherapeutic agent that is highly ototoxic. Animal studies and clinical trials have shown that thiosulfates can protect against platinum-induced ototoxicity. This study investigated a new model for CDDP ototoxici
Autor:
Jin Fu Zhou, D. Thomas Dickey, James P. Wicksted, Kenneth E. Bartels, John G. Kirkpatrick, Steven A. Schafer, Ronald Powell
Publikováno v:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII.
Normal non-pigmented bovine eyelids in two Hereford cows under general anesthesia were treated with diode laser (805 nm) in a power range of 3 - 6.5 watts. Tissue temperatures were measured in areas infiltrated with 0.25% indocyanine green (ICG) solu
Autor:
George A. Henry, Donald J. Hayes, David B. Wallace, D. Thomas Dickey, Robert E. Nordquist, Kenneth E. Bartels, Steven A. Schafer, Ernest L. Stair, Christopher J. Frederickson, Ronald Powell
Publikováno v:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VIII.
Use of holmium laser energy for vaporization/coagulation of the nucleus pulposus in canine intervertebral discs has been previously reported and is currently being applied clinically in veterinary medicine. The procedure was originally developed in t
Autor:
Ronald Powell, Ernest L. Stair, Robert E. Nordquist, D. Thomas Dickey, Randall J. Willis, Steven A. Schafer, John S. Hurd, Donald F. Hults, Kenneth E. Bartels
Publikováno v:
SPIE Proceedings.
This study evaluates tissue coagulation and ablation effects in the prostate gland of the canine model when a diode laser (805 nm-Diomed 25R-Surgimedics/ESP, The Woodlands, Texas) and an angled fiber configuration (1000 (mu) 20 degree bent-Surgimedic