Zobrazeno 1 - 10
of 369
pro vyhledávání: '"D. Teasdale"'
Autor:
Louis L’Hôte, Ian Light, Valeria Mattiangeli, Matthew D. Teasdale, Áine Halpin, Lionel Gourichon, Felix M. Key, Kevin G. Daly
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Brucella melitensis is a major livestock bacterial pathogen and zoonosis, causing disease and infection-related abortions in small ruminants and humans. A considerable burden to animal-based economies today, the presence of Brucella in Neoli
Externí odkaz:
https://doaj.org/article/4c3c0326461d406fbdc3bbff53607eb3
Autor:
Pei Ying Ng, Amy B. P. Ribet, Qiang Guo, Benjamin H. Mullin, Jamie W. Y. Tan, Euphemie Landao-Bassonga, Sébastien Stephens, Kai Chen, Jinbo Yuan, Laila Abudulai, Maike Bollen, Edward T. T. T. Nguyen, Jasreen Kular, John M. Papadimitriou, Kent Søe, Rohan D. Teasdale, Jiake Xu, Robert G. Parton, Hiroshi Takayanagi, Nathan J. Pavlos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Despite the importance of osteoclast secretory lysosomes in bone digestion, the proteins that regulate them remain ill defined. Here, the authors identify Slc37a2 as a secretory lysosome sugar transporter that is required for maintenance of skeletal
Externí odkaz:
https://doaj.org/article/cfbfda3751ad47868d62c17e221301bd
Publikováno v:
Cells, Vol 11, Iss 21, p 3358 (2022)
Mammalian retromer complex contributes to multiple early endosome-associated trafficking pathways whose origins are dependent on which sorting nexin (SNX) they are complexed with. In an attempt to dissect out the contribution of individual retromer
Externí odkaz:
https://doaj.org/article/22cb878a2c8d4e82912c23e0b5bc3ca5
Autor:
Sarah Fiddyment, Matthew D. Teasdale, Jiří Vnouček, Élodie Lévêque, Annelise Binois, Matthew J. Collins
Publikováno v:
Heritage Science, Vol 7, Iss 1, Pp 1-10 (2019)
Abstract Biocodicology, the study of the biological information stored in manuscripts, offers the possibility of interrogating manuscripts in novel ways. Exploring the biological data associated to parchment documents will add a deeper level of under
Externí odkaz:
https://doaj.org/article/a8e565a8bffd4038a1bc535d594f6981
Autor:
Mintu Chandra, Yanni K.-Y. Chin, Caroline Mas, J. Ryan Feathers, Blessy Paul, Sanchari Datta, Kai-En Chen, Xinying Jia, Zhe Yang, Suzanne J. Norwood, Biswaranjan Mohanty, Andrea Bugarcic, Rohan D. Teasdale, W. Mike Henne, Mehdi Mobli, Brett M. Collins
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Phox homology (PX) domains are membrane interacting domains that bind to various lipids. Here authors screen all human PX domains systematically for their phospholipid preferences and define four classes and provide the basis for defining and predict
Externí odkaz:
https://doaj.org/article/837519800813434db7bd127742edba4b
Autor:
Ioannis Kontopoulos, Kirsty Penkman, Victoria E Mullin, Laura Winkelbach, Martina Unterländer, Amelie Scheu, Susanne Kreutzer, Henrik B Hansen, Ashot Margaryan, Matthew D Teasdale, Birgit Gehlen, Martin Street, Niels Lynnerup, Ioannis Liritzis, Adamantios Sampson, Christina Papageorgopoulou, Morten E Allentoft, Joachim Burger, Daniel G Bradley, Matthew J Collins
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235146 (2020)
The recovery and analysis of ancient DNA and protein from archaeological bone is time-consuming and expensive to carry out, while it involves the partial or complete destruction of valuable or rare specimens. The fields of palaeogenetic and palaeopro
Externí odkaz:
https://doaj.org/article/f5fced8d050e47a098488355bce1586f
Autor:
Markus C. Kerr, Guillermo A. Gomez, Charles Ferguson, Maria C. Tanzer, James M. Murphy, Alpha S. Yap, Robert G. Parton, Wilhelmina M. Huston, Rohan D Teasdale
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Chlamydiae replicate in host cells within specialised vacuoles (inclusions), which are eventually ruptured to liberate the bacteria, leading to cell lysis. Here, Kerret al. use a laser ablation technique and videomicroscopy to show that inclusion rup
Externí odkaz:
https://doaj.org/article/5830fce444594ccebf7060c3ecb75ba5
Autor:
Rui Martiniano, Anwen Caffell, Malin Holst, Kurt Hunter-Mann, Janet Montgomery, Gundula Müldner, Russell L. McLaughlin, Matthew D. Teasdale, Wouter van Rheenen, Jan H. Veldink, Leonard H. van den Berg, Orla Hardiman, Maureen Carroll, Steve Roskams, John Oxley, Colleen Morgan, Mark G. Thomas, Ian Barnes, Christine McDonnell, Matthew J. Collins, Daniel G. Bradley
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Here, Martiniano et al. examine the genetic structure of northern Britain in the late BC/early AD using ancient genome sequencing of 9 individuals. They uncover evidence of far-reaching Roman and later Anglo-Saxon migrations within a background of Br
Externí odkaz:
https://doaj.org/article/6aeb3e80dace414189f881c3efb62b98
Autor:
János Dani, Cristina Gamba, Michael Hofreiter, Matthew D. Teasdale, László Domboróczki, Thomas Higham, Eppie R. Jones, Ron Pinhasi, Ivett Kővári, Russell L. McLaughlin, Alasdair Whittle, Valeria Mattiangeli, Gloria Gonzalez-Fortes, Daniel G. Bradley, Alexandra Anders, Ildikó Pap, Pál Raczky
Publikováno v:
Nature Communications
The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bf5f7a1848b303fbd8315594560aad
Publikováno v:
Essays in Biochemistry
To date, mechanistic treatments targeting the initial cause of Parkinson's disease (PD) are limited due to the underlying biological cause(s) been unclear. Endosomes and their associated cellular homeostasis processes have emerged to have a significa