Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D. T. Connolly"'
Autor:
Matthias Clauss, P C Familletti, F. Wang, H Gerlach, J Brett, D. T. Connolly, Marlene Gerlach, Y. C.E. Pan, David M. Stern, J. V. Olander
Publikováno v:
The Journal of Experimental Medicine
Systemic infusion of low concentrations of tumor necrosis factor/cachectin (TNF) into mice that bear TNF-sensitive tumors leads to activation of coagulation, fibrin formation, and occlusive thrombosis exclusively within the tumor vascular bed. To ide
Autor:
J A, Sikorski, D T, Connolly
Publikováno v:
Current opinion in drug discoverydevelopment. 4(5)
Cholesteryl ester transfer protein (CETP) has been an important but controversial target for elevating HDLc (high density lipoprotein cholesterol) and treating atherosclerosis. Significant progress toward inhibiting CETP has occurred on several front
Autor:
N. Mcclure, D. T. Connolly, David Robertson, R. V. Haning, David L. Healy, J. Sullivan, L. Beaton, Peter Rogers
Publikováno v:
Lancet (London, England). 344(8917)
We investigated the role of vascular endothelial growth factor (VEGF) in ovarian hyperstimulation syndrome (OHSS). Two similar peaks of permeability activity were seen in OHSS ascites and liver ascites spiked with recombinant human VEGF (rhVEGF); no
Publikováno v:
Cancer research. 50(6)
Rodent and human tumor cell lines secrete a potent vascular permeability factor (VPF) which causes a rapid and substantial increase in microvascular permeability to plasma proteins without causing mast cell degranulation, or endothelial cell damage o
Autor:
D T Connolly, J V Olander, D Heuvelman, R Nelson, R Monsell, N Siegel, B L Haymore, R Leimgruber, J Feder
Publikováno v:
Journal of Biological Chemistry. 264:20017-20024
A cDNA having a base sequence for human vascular permeability factor has been cloned and characterized and the amino acid sequence of the human vascular permeability factor protein has been determined.
Publikováno v:
Journal of Biological Chemistry. 256:12940-12948
The binding of 125I-asialoorosomucoid and the isolated rabbit hepatic lectin were studied at 0 degrees C. The steady state binding data were analyzed both by a direct curve-fitting procedure that utilizes nonlinear least squares regression analysis,
Publikováno v:
Journal of Biological Chemistry. 257:939-945
Synthetic cluster glycosides containing either one, two, or three galactosyl or lactosyl residues per ligand were used to test the effect of carbohydrate clustering on binding by the rabbit hepatic Gal/GalNAc-binding lectin using either isolated rabb
Publikováno v:
Biochemical Journal. 214:421-431
Rabbit hepatocytes were isolated by a collagenase perfusion technique, and used to study the binding and endocytosis of the glycoprotein, asialo-orosomucoid, and the neoglycoprotein, Gal39-bovine serum albumin. Both of these proteins contain exposed
Publikováno v:
Journal of Biological Chemistry. 257:11489-11496
Epidermal growth factor (EGF) receptors extracted with Triton X-100 from human skin fibroblasts and A431 epidermoid carcinoma cells rapidly lose EGF-binding activity precipitable with polyethylene glycol. The presence of concanavalin A which can cros
Publikováno v:
The Journal of biological chemistry. 257(19)
Epidermal growth factor (EGF) receptors extracted with Triton X-100 from human skin fibroblasts and A431 epidermoid carcinoma cells rapidly lose EGF-binding activity precipitable with polyethylene glycol. The presence of concanavalin A which can cros