Zobrazeno 1 - 10
of 114
pro vyhledávání: '"D. T. Armstrong"'
Publikováno v:
Bioscientifica Proceedings.
Studies of isolated cell types from sheep follicles revealed several functional changes which occur during follicular maturation. Cyclic AMP production by granulosa cells from the smallest follicles studied (1-3 mm diameter) was stimulated by FSH but
Publikováno v:
Society of Reproduction and Fertility supplement. 62
Insemination transmits to the female reproductive tract constituents of seminal plasma that target uterine epithelial cells to activate a cascade of inflammatory and immunological changes. Experiments in rodents show seminal factor signalling acts to
Autor:
T E, Hickey, D L, Marrocco, F, Amato, L J, Ritter, R J, Norman, R B, Gilchrist, D T, Armstrong
Publikováno v:
Biology of reproduction. 73(4)
In this study, we test the hypothesis that the growth-promoting action of androgens on granulosa cells requires paracrine signaling from the oocyte. Mural granulosa cells (MGCs) from small antral (1-3 mm) prepubertal pig follicles were cultured in th
Publikováno v:
Biology of reproduction. 71(4)
Compared with oocytes matured in vivo, in vitro-matured oocytes are compromised in their capacity to support early embryo development. Delaying spontaneous in vitro meiotic maturation using specific phosphodiesterase (PDE) isoenzyme inhibitors may pe
Publikováno v:
Biology of reproduction. 71(4)
Oxygen concentrations used during in vitro embryo culture can influence embryo development, cell numbers, and gene expression. Here we propose that the preimplantation bovine embryo possesses a molecular mechanism for the detection of, and response t
Publikováno v:
Biology of reproduction. 71(1)
Androgens acting via the androgen receptor (AR) have been implicated in regulation of folliculogenesis in many animal species. These effects are possibly mediated via enhancement of FSH and/or insulin-like growth factor (IGF)-I activity in granulosa
Autor:
P S, Duggal, N K, Ryan, K H, Van der Hoek, L J, Ritter, D T, Armstrong, D A, Magoffin, R J, Norman
Publikováno v:
Reproduction (Cambridge, England). 123(6)
Leptin is expressed by adipocytes and is thought to play a role in regulating food intake and in reproduction. It has been demonstrated that acute leptin administration to immature gonadotrophin-primed rats in vivo inhibits ovulation and causes a dec
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(3)
CD40 binding produces multifaceted growth signals in normal and malignant B cells, whereas its physiological role is less well characterized in epithelial cancers. We examined the growth outcome of CD40 ligation in human breast cancer cells, using CD
Publikováno v:
Biology of reproduction. 63(3)
Cumulus cells and mural granulosa cells (MGC) are phenotypically different and there is now evidence suggesting that the oocyte plays an active role in determining the fate of follicular somatic cells. This study investigates the role of oocyte-secre
Publikováno v:
Biology of reproduction. 56(6)
Bovine oviductal monolayer and vesicle primary cultures express insulin-like growth factor (IGF)-I and -II mRNAs and polypeptides. Early bovine embryos also express IGF-I, IGF-II, IGF-I receptor, IGF-II receptor, and insulin receptor mRNAs. This stud