Zobrazeno 1 - 10
of 54
pro vyhledávání: '"D. Stuparu"'
Autor:
Katharina Lückerath, Liu Wei, Wolfgang P. Fendler, Susan Evans-Axelsson, Andreea D. Stuparu, Roger Slavik, Christine E. Mona, Jeremie Calais, Matthew Rettig, Robert E. Reiter, Ken Herrmann, Caius G. Radu, Johannes Czernin, Matthias Eiber
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Background Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) is a promising yet not curative approach in castration-resistant (CR) prostate cancer (PC). Rational combination therapies may improve treatment efficacy
Externí odkaz:
https://doaj.org/article/ee03584d5b0e4659899e23720969876c
Autor:
Katharina Lueckerath, Johannes Czernin, Caius G. Radu, David W. Dawson, Chloe Cheng, Andreea D. Stuparu, Roger Slavik, Joel Almajano, Christine E. Mona, Clara E. Magyar, Catherine Meyer, Kyle Current
Purpose:Prostate-specific membrane antigen (PSMA) targeting radioligands deliver radiation to PSMA-expressing cells. However, the relationship between PSMA levels and intralesion heterogeneity of PSMA expression, and cytotoxic radiation by radioligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87bfc94930ce722193b7ac6b0a74d12
https://doi.org/10.1158/1078-0432.c.6528194.v1
https://doi.org/10.1158/1078-0432.c.6528194.v1
Autor:
Katharina Lueckerath, Johannes Czernin, Caius G. Radu, David W. Dawson, Chloe Cheng, Andreea D. Stuparu, Roger Slavik, Joel Almajano, Christine E. Mona, Clara E. Magyar, Catherine Meyer, Kyle Current
Absolute tumor volumes and bodyweights
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89269533e5cf5d9037b5a1778f1afdd5
https://doi.org/10.1158/1078-0432.22472327
https://doi.org/10.1158/1078-0432.22472327
Autor:
Katharina Lueckerath, Johannes Czernin, Caius G. Radu, David W. Dawson, Chloe Cheng, Andreea D. Stuparu, Roger Slavik, Joel Almajano, Christine E. Mona, Clara E. Magyar, Catherine Meyer, Kyle Current
Relative tumor volumes, 177Lu-/225Ac-PSMA617 uptake and 53BP1 IRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e29859716774e169155b39d7590995
https://doi.org/10.1158/1078-0432.22472312
https://doi.org/10.1158/1078-0432.22472312
Akademický článek
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Autor:
Aneta Turlik, Robert Damoiseaux, Joanna Li, Timothy R. Donahue, Daniel L. Sun, Selena Hernandez, Evan R. Abt, Wei Chen, Kendall N. Houk, Jeffrey I. Zink, Caius G. Radu, Andreea D. Stuparu, Karen Reue, Chi-An Cheng, Ethan W. Rosser, Johannes Czernin, Laurent Vergnes, Michael E. Jung, Christine E. Mona, Vincent Lok, Juno Van Valkenburgh, Xiaohong Chen, Roy D. Pan, Soumya Poddar, Thuc Le, Janet Song
Publikováno v:
RSC medicinal chemistry, vol 11, iss 3
A potent class of isoquinoline-based α-N-heterocyclic carboxaldehyde thiosemicarbazone (HCT) compounds has been rediscovered; based upon this scaffold, three series of antiproliferative agents were synthesized through iterative rounds of methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c2c5577be17a8d967044dcbbd0e9db
https://escholarship.org/uc/item/37j7d1kf
https://escholarship.org/uc/item/37j7d1kf
Autor:
Christine E. Mona, Magnus Dahlbom, Soumya Poddar, Caius G. Radu, Mark D. Girgis, Liu H. Wei, Katharina Lückerath, Woosuk Kim, Roger Slavik, Susan Evans-Axelsson, Andreea D. Stuparu, Catherine Meyer, Johannes Czernin
Publikováno v:
Theranostics, vol 10, iss 6
Theranostics
Theranostics
²²⁵Ac-PSMA-617 targeted-therapy has demonstrated efficacy in 75-85% of patients; however, responses are not durable. We aimed to establish translatable mouse models of disseminated prostate cancer (PCa) to evaluate effectiveness of ²²⁵Ac-PSMA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1ad8c4a76c82aba8cb4f4f2378cb50
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85079687942
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85079687942
Autor:
Roger Slavik, Clara E. Magyar, Andreea D. Stuparu, Catherine Meyer, Kyle Current, Caius G. Radu, Johannes Czernin, David W. Dawson, Christine E. Mona, Chloe M. Cheng, Joel Almajano, Katharina Lueckerath
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 12
Purpose: Prostate-specific membrane antigen (PSMA) targeting radioligands deliver radiation to PSMA-expressing cells. However, the relationship between PSMA levels and intralesion heterogeneity of PSMA expression, and cytotoxic radiation by radioliga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea2ba8206d3b896b738272c8ec7acc4
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85086523193
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85086523193
Autor:
Daniel L, Sun, Soumya, Poddar, Roy D, Pan, Ethan W, Rosser, Evan R, Abt, Juno, Van Valkenburgh, Thuc M, Le, Vincent, Lok, Selena P, Hernandez, Janet, Song, Joanna, Li, Aneta, Turlik, Xiaohong, Chen, Chi-An, Cheng, Wei, Chen, Christine E, Mona, Andreea D, Stuparu, Laurent, Vergnes, Karen, Reue, Robert, Damoiseaux, Jeffrey I, Zink, Johannes, Czernin, Timothy R, Donahue, Kendall N, Houk, Michael E, Jung, Caius G, Radu
Publikováno v:
RSC Med Chem
A potent class of isoquinoline-based α-N-heterocyclic carboxaldehyde thiosemicarbazone (HCT) compounds has been rediscovered; based upon this scaffold, three series of antiproliferative agents were synthesized through iterative rounds of methylation
Autor:
Liu Wei, Jeremie Calais, Robert E. Reiter, Christine E. Mona, Andreea D. Stuparu, Matthias Eiber, Woosuk Kim, Johannes Czernin, Roger Slavik, Caius G. Radu, Katharina Lückerath, Ken Herrmann, Wolfgang P. Fendler, Matthew Rettig
Publikováno v:
Journal of Nuclear Medicine. 59:1392-1397
To improve prostate-specific membrane antigen (PSMA)–targeted theranostic approaches, robust murine models of prostate cancer are needed. However, important characteristics of preclinical PSMA imaging—that is, the reproducibility of the imaging s