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pro vyhledávání: '"D. Steeves"'
Akademický článek
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Publikováno v:
BMC Medical Research Methodology, Vol 16, Iss 1, Pp 1-13 (2016)
Abstract Background A number of potential therapeutic approaches for neurological disorders have failed to provide convincing evidence of efficacy, prompting pharmaceutical and health companies to discontinue their involvement in drug development. Li
Externí odkaz:
https://doaj.org/article/725e0346eeb244c5830462d786eeff9b
Autor:
John D. Steeves, Chih-Ying Li, S Charlifue, Linda Jones, David Weitzenkamp, Gale G. Whiteneck
Publikováno v:
Neurorehabil Neural Repair
Background. In spinal cord injury, there are multiple databases containing information on functional recovery, but data cannot be pooled or compared due to differences in how function is measured. A crosswalk is needed to link or convert scores betwe
Autor:
Vieri Failli, Armin Curt, Michael G. Fehlings, Andrew R. Blight, Naomi Kleitman, Mark H. Tuszynski, Daniel P. Lammertse, James W. Fawcett, John D. Steeves, James D. Guest, Jane T.C. Hsieh
Publikováno v:
Top Spinal Cord Inj Rehabil
Experiencing a spinal cord injury (SCI) is extremely distressing, both physically and psychologically, and throws people into a complex, unfamiliar world of medical procedures, terminology, and decision making. You may have already had surgery to sta
Adaptive trial designs for spinal cord injury clinical trials directed to the central nervous system
Autor:
Linda Jones, Rϋediger Rupp, Andrew R. Blight, Daniel P. Lammertse, John L.K. Kramer, Frank W. Rockhold, John D. Steeves, James D. Guest, Steven Kirshblum, Mary Jane Mulcahey
Publikováno v:
Spinal Cord. 58:1235-1248
Narrative review. To provide an overview of adaptive trial designs, and describe how adaptive methods can address persistent challenges encountered by randomized controlled trials of people with spinal cord injury (SCI). With few exceptions, adaptive
Autor:
Adrian Cathomen, Laura Sirucek, Tim Killeen, Rainer Abel, Doris Maier, Norbert Weidner, Rüdiger Rupp, Torsten Hothorn, John D. Steeves, Armin Curt, Marc Bolliger
Publikováno v:
Neurorehabilitation and Neural Repair, 36 (4-5)
Background New therapeutic approaches in neurological disorders are progressing into clinical development. Past failures in translational research have underlined the critical importance of selecting appropriate inclusion criteria and primary outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c2f0e7946a49eef696dbde53311c28
Autor:
Jana, Dengler, John D, Steeves, Armin, Curt, Munish, Mehra, Christine B, Novak, Yorck-Bernhard, Kalke
Publikováno v:
Spinal cord. 60(10)
Retrospective cohort study.To quantify spontaneous upper extremity motor recovery between 6 and 12 months after spinal cord injury (SCI) to help guide timing of nerve transfer surgery to improve upper limb function in cervical SCI.Nineteen European S
Akademický článek
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Akademický článek
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Publikováno v:
BMC Medical Research Methodology
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-14 (2020)
Background Sum scores of ordinal outcomes are common in randomized clinical trials. The approaches routinely employed for assessing treatment effects, such as t-tests or Wilcoxon tests, are not particularly powerful in detecting changes in relevant p