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pro vyhledávání: '"D. Sharpstone"'
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Publikováno v:
HIV Medicine. 1:102-106
Objective As the pro-inflammatory cytokine tumour necrosis factor-alpha is greater in microsporidiosis than cryptosporidiosis, there may be a distinct metabolic response between the two organisms. Design Male HIV seropositive subjects with an untreat
Autor:
Brian Gazzard, Chris Taylor, Ingvar Bjarnason, G Sigthorsson, D Sharpstone, M Coutts, R Sherwood, K Hodgson, I S Menzies
Publikováno v:
Scandinavian Journal of Gastroenterology. 35:599-606
Background: Gastrointestinal symptoms are distressing features of human immunodeficiency virus (HIV) ) infection, and management is often empirical, including withdrawal of dietary lactose. We assessed the prevalence and severity of intestinal disacc
Autor:
P Engrand, Derek C. Macallan, N.I.J. Paton, Hazel M. Ross, Marinos Elia, Brian Gazzard, P.J. Newton, George E. Griffin, Eric Milne, J. Cotton, D Sharpstone, S Shah, Alexander Graham Calder
Publikováno v:
AIDS. 13:1195-1202
Objectives: A 12-week course of recombinant human growth hormone is an effective but expensive therapy for established HIV-related wasting. Wasting in HIV disease is often episodic, coinciding with bouts of acute opportunistic infection. We hypothesi
Autor:
Ingvar Bjarnason, Chris Taylor, P Neild, Brian Gazzard, D Sharpstone, R Sherwood, C Hodgson, Roger Crane
Publikováno v:
Gut. 45:70-76
BACKGROUND—Diarrhoea in AIDS is associated with anorexia and weight loss. The importance of gastrointestinal transit in such symptoms has not been addressed. AIMS—To assess jejunal to caecal transit times in subjects with AIDS related diarrhoea a
Publikováno v:
Clinical and Experimental Immunology. 111:559-563
SUMMARYHIV+ individuals with human CMV (HCMV) reactivation have a CD3 receptor-mediated T cell hyporesponsiveness when compared with CD4-matched HIV+ and HCMV−control groups. The impairment of proliferation was not reversed by exogenous IL-2. A typ
Publikováno v:
International Journal of STD & AIDS. 8:700-703
Extrapolation of data from energy balance studies in HIV-seropositive men to HIV-seropositive women may be inaccurate due to gender differences in body composition, hormones and metabolism. If women have a different metabolic response to the human im
Autor:
Margaret S. Phelan, Margaret R. Hancock, Mark Nelson, Claire P. Murray, David A. Reaveley, Hazel M. Ross, Brian Gazzard, Roger Crane, Ian S Menzies, Alessandro Cozzi Lepri, D Sharpstone
Publikováno v:
AIDS. 10:1377-1384
Objectives : Body weight is regulated by the balance between energy intake and energy expenditure, but the influence of HIV infection on energy balance has not been fully examined. The main objectives of this study were (1) to assess the effect of HI