Zobrazeno 1 - 10
of 33
pro vyhledávání: '"D. S. Wilbur"'
Autor:
Kevin D. John, Silvia S. Jurisson, Alan R. Ketring, B. Ballard, Jonathan W. Engle, Francois M. Nortier, Joel R. Maassen, Michael E. Fassbender, Cathy S. Cutler, Eva R. Birnbaum, J.W. Lenz, D. S. Wilbur
Publikováno v:
Radiochimica Acta. 101:339-346
Rhenium-186g (T 1/2= 89.2 h) is a β − emitter suitable for therapeutic applications. Current production methods rely on reactor production via 185Re(n,γ) which results in low specific activities, thereby limiting its use. Production by p,d activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ac54897bdb43fe64579ce0ecff4385
https://doi.org/10.1524/ract.2013.2031
https://doi.org/10.1524/ract.2013.2031
Autor:
D S Wilbur, S W Hadley
Publikováno v:
Bioconjugate Chemistry. 1:154-161
The preparations and conjugations of 2,3,5,6-tetrafluorophenyl 5-[125I/131I]iodo-4-pentenoate (7a) and 2,3,5,6-tetrafluorophenyl 3,3-dimethyl-5-[125I/131I]iodo-4-pentenoate (7b) to monoclonal antibodies are reported. Reagents 7a and 7b were prepared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7f9839a8bc458296caa188bdccad6a
https://doi.org/10.1021/bc00002a011
https://doi.org/10.1021/bc00002a011
Autor:
D S, Wilbur
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db5b227b463851b78f8edea103077fc6
https://pubmed.ncbi.nlm.nih.gov/11585865
https://pubmed.ncbi.nlm.nih.gov/11585865
Publikováno v:
Isotope Production and Applications in the 21st Century.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e317be92616ea7818ddfb7c58fa27819
https://doi.org/10.1142/9789812793867_0086
https://doi.org/10.1142/9789812793867_0086
Autor:
M D Hylarides, D S Wilbur
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 18:363-365
A preliminary study involving the radiolabeling of an anti-melanoma antibody through conjugation of a radiobrominated small molecule, N-succinimidyl para-[77Br]bromobenzoate, has been accomplished in 22% overall yield when no-carrier-added radiobromi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8103d783d488ee4feec754c140d34a36
https://doi.org/10.1016/0883-2897(91)90133-6
https://doi.org/10.1016/0883-2897(91)90133-6
Autor:
D. S. Wilbur
The research effort was directed at evaluating reagents and conditions for targeting the alpha-emitting radionuclide Bi-213 to breast cancer. Initial studies used human tumor xenografts (MCF-7) in athymic mice to demonstrate tumor targeting and blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a898f5b3382a58db048a52fca82d5fa8
https://doi.org/10.21236/ada390786
https://doi.org/10.21236/ada390786
Autor:
D S Wilbur
The purpose of this research project was to develop conditions and reagents required for effective targeting of the alpha-emitting radionuclide At-211 to metastatic prostate cancer cells. In the studies conducted, three different approaches to 'preta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ea24c70cd71698c1fb5665f4de4718
https://doi.org/10.21236/ada374830
https://doi.org/10.21236/ada374830
Autor:
G R, McLean, P M, Pathare, D S, Wilbur, A C, Morgan, C S, Woodhouse, J W, Schrader, H J, Ziltener
Publikováno v:
Cancer research. 57(18)
Analogues of cyanocobalamin (CN-Cbl), with functional groups attached to either the various propionamide groups of the corrin ring or to the ribose-nucleotide linker arm, have been evaluated in a cobalamin (Cbl)-dependent in vitro cell growth assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2968ed15fa0f23d636c2a9f4f4cbf6ec
https://pubmed.ncbi.nlm.nih.gov/9307287
https://pubmed.ncbi.nlm.nih.gov/9307287
Publikováno v:
Bioconjugate chemistry. 8(2)
Several cobalamin (Cbl) dimers have been prepared for evaluation as potential antiproliferative agents in the treatment of AIDS-related lymphoma. The Cbl dimers were synthesized by cross-linking Cbl carboxylates, produced by acid hydrolysis of the b-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27e2569660c8603b83bffcae2c8829be
https://pubmed.ncbi.nlm.nih.gov/9095356
https://pubmed.ncbi.nlm.nih.gov/9095356
Autor:
George E. Laramore, Mark Phillips, R. Risler, Thomas W. Griffin, D. S. Wilbur, J. C. Livesey, Thomas A. Buchholz, P. Wootton
Publikováno v:
Cancer Neutron Capture Therapy ISBN: 9781475795691
In parallel with boron neutron capture therapy (BNCT), fast neutron radiotherapy began shortly after the discovery of the neutron by Chadwick. The earliest clinical studies showed considerable toxicity and little efficacy1, and the field languished u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::546c2d567ea44fe5433768da4d5e4f0c
https://doi.org/10.1007/978-1-4757-9567-7_110
https://doi.org/10.1007/978-1-4757-9567-7_110