Zobrazeno 1 - 8
of 8
pro vyhledávání: '"D. S. Swafford"'
Autor:
D. S. Swafford, Kristen J. Nikula, Gregory Kelly, Charles E. Mitchell, Marshall W. Anderson, Gregory L. Finch, Fletcher F. Hahn, Steven A. Belinsky
Publikováno v:
Environmental Health Perspectives
Activation of the K-ras protooncogene and inactivation of the p53 tumor suppressor gene are events common to many types of human cancers. Molecular epidemiology studies have associated mutational profiles in these genes with specific exposures. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933a390e410adf7540106433ffc009d0
https://doi.org/10.1289/ehp.97105s4901
https://doi.org/10.1289/ehp.97105s4901
Autor:
James G. Herman, Johannes Tesfaigzi, D. S. Swafford, Susan K. Middleton, Steven A. Belinsky, Kristen J. Nikula, William A. Palmisano, Stephen B. Baylin
Publikováno v:
Molecular and Cellular Biology. 17:1366-1374
The p16INK4a (p16) tumor suppressor gene is frequently inactivated by homozygous deletion or methylation of the 5' CpG island in cell lines derived from human non-small-cell lung cancers. However, the frequency of dysfunction in primary tumors appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8c7c2e5733cbfbe950593530213a1b
https://doi.org/10.1128/mcb.17.3.1366
https://doi.org/10.1128/mcb.17.3.1366
Publikováno v:
Toxicologic Pathology. 25:2-12
Inhalation of beryllium (Be) has been associated with 2 syndromes: an acute chemical pneumonitis and a granulomatous lung disease known as chronic beryllium disease (CBD). Key to the pathogenesis of CBD is a delayed-type hypersensitivity reaction, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9283e8d25193f4146d06f0a3eeab58ad
https://doi.org/10.1177/019262339702500102
https://doi.org/10.1177/019262339702500102
Publikováno v:
Carcinogenesis. 18:115-120
Recent allelotyping of chemical-induced lung tumors in hybrid mice has detected loss of heterozygosity on chromosome 4 in a region involving the interferon-{alpha} (IFN-{alpha}) gene cluster that is syntenic to human chromosome 9p21-22, the location
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ee6f84c128b53dc442b344fa3dd6ab
https://doi.org/10.1093/carcin/18.1.115
https://doi.org/10.1093/carcin/18.1.115
Publikováno v:
Carcinogenesis. 16:1215-1221
Inhalation of diesel exhaust (DE), which contains soot particles with adsorbed mutagenic organic compounds, and its virtually mutagen-free soot particle analog, carbon black (CB), produce similar types and prevalences of pulmonary neoplasms in chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c834bd8762b798985d8e30ebb44f904a
https://doi.org/10.1093/carcin/16.5.1215
https://doi.org/10.1093/carcin/16.5.1215
Autor:
D. S. Swafford, B.A. Muggenburg, Raymond A. Guilmette, David E. Bice, Patrick J. Haley, D.R. Davila
Publikováno v:
International Journal of Radiation Biology. 61:123-133
Young Beagle dogs were exposed by inhalation to aerosols of 239PuO2 and observed for their lifespans as part of a large, ongoing study of the biological effects of inhaled radionuclides. The purpose of our study was to compare certain immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b13965386cf1ed337a65537a4ff08d
https://doi.org/10.1080/09553009214550691
https://doi.org/10.1080/09553009214550691
Autor:
Mark D. Hoover, D. S. Swafford, N. F. Johnson, Bruce A. Muggenburg, P. J. Haley, Gregory L. Finch
Publikováno v:
Scopus-Elsevier
We have reported that dogs exposed twice to aerosols of beryllium oxide (BeO) developed Be-specific immune responses within the lung, along with granulomatous and fibrotic lung lesions. To evaluate the specificity of the immune response, lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57296e7ccbe753c564a21727febbb44
https://pubmed.ncbi.nlm.nih.gov/9436046
https://pubmed.ncbi.nlm.nih.gov/9436046
Aberrations on the short arm of chromosome 9 are among the earliest genetic changes in human cancer. p16{sup INK4a} is a candidate tumor suppressor gene that lies within human 9p21, a chromosome region associated with frequent loss of heterozygosity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d0b64f79ab14c2e926283a61d9db90
https://doi.org/10.2172/381388
https://doi.org/10.2172/381388
