Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D. S. Neufeld"'
Autor:
Erlinda Concepcion, G. O'connor, Terry F. Davies, David A. Greenberg, Sheila H. Roman, D. S. Neufeld
Publikováno v:
Autoimmunity. 14:237-241
Autoimmune thyroid disease (AITD) is often familial and serological HLA disease associations have been described in many different populations. However, such HLA disease associations are weak and the precise molecular contribution of HLA antigens to
Autor:
Terry F. Davies, D. S. Neufeld
Publikováno v:
Endocrinology. 127:1254-1259
The major histocompatibility complex (MHC) genes, primarily of the MHC class II region, are linked to increased susceptibility to autoimmune thyroid disease in animals and humans. The quantity of MHC class II antigens that are expressed on the approp
Autor:
D S, Neufeld
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 75
Publikováno v:
Clinical immunology and immunopathology. 67(2)
The induction of HLA class II antigens on human thyroid epithelial cells has been shown to be an intimate part of the pathology of autoimmune thyroid disease and may also be relevant to the natural history of thyroid neoplasia since thyroid cancer ce
Autor:
Terry F. Davies, D. S. Neufeld
Publikováno v:
Molecular Endocrinology. 2:507-511
We have reexamined 1B-6 cells, a cloned line of FRTL-5 rat thyroid cells in order to determine whether such cells demonstrate constitutive MHC class II gene expression. A new homologous cDNA probe for the RT1.D alpha-chain region was developed and pr
Publikováno v:
Molecular and Cellular Biology. 7:2794-2802
Simian virus 40 (SV40)-mediated transformation of human diploid fibroblasts has provided an effective experimental system for studies of both "senescence" in cell culture and carcinogenesis. Previous interpretations may have been complicated, however
Publikováno v:
Molecular Endocrinology. 3:758-762
We have previously demonstrated that recombinant gamma-interferon (gamma IF) inhibits thyroid cell proliferation in vitro. We now demonstrate differential regulation of thyroid cell genes by recombinant gamma IF, as evidenced by data obtained measuri
Publikováno v:
Endocrinology
We have previously demonstrated that cultured rat thyroid cells do not exhibit constitutive expression of major histocompatability (MHC) class II antigens. Using reovirus types 1 and 3, we infected 1B-6 cells (a cloned derivative of the Fisher rat ce
Publikováno v:
Molecular and cellular biology. 7(8)
Simian virus 40 (SV40)-mediated transformation of human diploid fibroblasts has provided an effective experimental system for studies of both "senescence" in cell culture and carcinogenesis. Previous interpretations may have been complicated, however
Publikováno v:
Endocrinology. 121(6)
Major histocompatibility (MHC) class II antigen expression by thyroid epithelial cells has been widely implicated in the pathogenesis of autoimmune thyroid disease. We have examined rat MHC (RT1) class II antigen gene regulation in 1B-6 cells, cloned