Zobrazeno 1 - 10
of 39
pro vyhledávání: '"D. S. Kumararatne"'
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 1(3)
Although asymptomatic haemophiliacs have been shown to have abnormalities of their immune response, independent of HIV, clinical evidence of significant immunosuppression is limited. The only clinical report has been an outbreak of M. tuberculosis in
Publikováno v:
Paediatrics and International Child Health. 35:69-71
Although neonatal vaccination with bacille Calmette-Guérin (BCG) is considered to be safe, complications with disseminated disease are associated with underlying immuno-deficiency disorders. A BCG-vaccinated 4-month-old girl of Sri Lankan parentage
Publikováno v:
QJM. 95:655-662
Background: Common variable immune deficiency (CVID) is prone to under‐diagnosis and may not reach relevant specialists until late in life. Morbidity is most commonly due to acute‐on‐chronic respiratory infections leading to respiratory failure
Publikováno v:
Drug Development Research. 53:105-116
Investigation of the P2X 7 receptor-associated signalling events following ATP stimulation of Mycobacterium bovis BCG-infected human macrophages revealed that ATP-mediated cell death and associated mycobacterial killing could be functionally uncouple
Autor:
Paul Warwicker, A. J. Howie, Judith A. Goodship, D. S. Kumararatne, Rosemary L. Donne, R. A. Thompson, Chris Taylor, Timothy H.J. Goodship
Publikováno v:
Nephrology Dialysis Transplantation. 14:1229-1233
the first, aVected individuals, particularly siblings usually residing in regions geographically related to outBackground. In a recent study of three families we have found that inherited haemolytic uraemic syn- breaks of HUS, suVer disease within da
Publikováno v:
Molecular Pathology. 49:M273-M277
Aims-To overcome the problems associated with proteolytic pretreatment of tissue sections for the detection of apoptosis.Methods-Formalin fixed, paraffin wax embedded tissue sections of reactive lymph nodes and biopsy specimens of Burkitt lymphoma we
Publikováno v:
Journal of Clinical Pathology. 47:405-410
AIMS--To evaluate two of the recent methods of coating microtitre plates in the enzyme linked immunosorbent assay (ELISA) for detecting human antibodies against meningococcal capsular polysaccharides A and C with a view to validating a specific menin
Publikováno v:
The Journal of Immunology. 150:4856-4866
Stimulation of human CD4+ T cell clones with appropriate specific peptides or with lectins in the absence of APC induces a substantial degree of cell death. We have investigated the mechanisms of induction of this cell death and show that it occurs b
Autor:
S. Y. Patel, D. S. Kumararatne
Publikováno v:
Clinical and Experimental Immunology. 124:169-171
High-dose intravenous immunoglobulin (IVIG) therapy has been effective in many autoimmune and systemic inflammatory diseases including polymyositis (PM) and dermatomyositis (DM). In the present study we evaluated the efficacy of IVIG using experiment
Publikováno v:
The Ceylon medical journal. 54(2)