Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D. S. Bredt"'
Autor:
A W, McGee, J R, Topinka, K, Hashimoto, R S, Petralia, S, Kakizawa, F W, Kauer, A, Aguilera-Moreno, R J, Wenthold, M, Kano, D S, Bredt, F, Kauer
Publikováno v:
The Journal of Neuroscience. 21:3085-3091
Membrane-associated guanylate kinases (MAGUKs) are abundant postsynaptic density (PSD)-95/discs large/zona occludens-1 (PDZ)-containing proteins that can assemble receptors and associated signaling enzymes at sites of cell–cell contact, including s
Publikováno v:
Glia. 31:181-192
Astrocytic inward rectifying K+ channels that participate in K+ spatial buffering in the central nervous system have been extensively investigated, but specific gene products have not been fully identified. We studied primary cultured reactive astroc
Autor:
Yang Guo, Alain S. Comtois, E. Zhu, D. S. Bredt, Michael T. Greenwood, Sabah N. A. Hussain, Q. El Dwairi
Publikováno v:
Scopus-Elsevier
Nitric oxide (NO) acts as an endogenous mediator in mature skeletal muscle. In this study, we investigated the regulation of the endothelial (eNOS) and neuronal (nNOS) isoforms of nitric oxide synthase (NOS) in skeletal-muscle development (rat diaphr
Publikováno v:
American Journal of Physiology-Cell Physiology. 266:C981-C989
The ultrastructural distribution and subcellular localization of nitric oxide synthase (NOS) immunoreactivity and its possible colocalization with vasoactive intestinal polypeptide (VIP) and substance P in the muscularis externa in canine ileum and c
Autor:
D. S. Bredt, David J. Sugarbaker, Jonathan S. Stamler, Lester Kobzik, Jeffrey M. Drazen, Charles J. Lowenstein, Benjamin Gaston
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 9:371-377
Nitric oxide synthase (NOS) produces nitric oxide, a mediator of potential importance in numerous physiologic and inflammatory processes in the lung. We localized constitutive NOS (c-NOS) and inducible NOS (i-NOS) within lung tissue by immunoperoxida
Publikováno v:
Acta physiologica Scandinavica. 179(2)
Nitric oxide synthases (NOSs) generate nitric oxide (NO) and the by-product l-citrulline, via the catalytic combination of l-arginine and molecular oxygen. In mammals, there are three NOS genes: nNOS (NOS1), iNOS (NOS2) and eNOS (NOS3). The molecular
Publikováno v:
Glia. 31(2)
Astrocytic inward rectifying K(+) channels that participate in K(+) spatial buffering in the central nervous system have been extensively investigated, but specific gene products have not been fully identified. We studied primary cultured reactive as
Autor:
A E, El-Husseini, J R, Topinka, J E, Lehrer-Graiwer, B L, Firestein, S E, Craven, C, Aoki, D S, Bredt
Publikováno v:
The Journal of biological chemistry. 275(31)
The postsynaptic density protein PSD-95 and related membrane-associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. Whereas PSD-95 and PSD-93 occur only at postsynaptic si
Publikováno v:
Neuron. 24(3)
Postsynaptic density 95 (PSD-95/SAP-90) is a membrane associated guanylate kinase (GK) PDZ protein that scaffolds glutamate receptors and associated signaling networks at excitatory synapses. Affinity chromatography identifies cypin as a major PSD-95
Publikováno v:
Science (New York, N.Y.). 284(5415)
The PDZ protein interaction domain of neuronal nitric oxide synthase (nNOS) can heterodimerize with the PDZ domains of postsynaptic density protein 95 and syntrophin through interactions that are not mediated by recognition of a typical carboxyl-term