Výsledky vyhledávání - "D. S. Latchman"

Autor: D. S. Latchman

Publikováno v: Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 351:471-474

The central dogma of molecular biology is that DNA makes RNA and RNA makes protein. Thus the genetic information in the DNA is first converted into an RNA molecule and in turn the information in the RNA is used to make a protein which exerts a partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10e48e8d760797ce082472920e85bd36
https://doi.org/10.1098/rstb.1996.0044

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Regulation of neuroblastoma growth and differentiation by the POU family transcription factors Brn-3a and Brn-3b (Review)

Autor: D. S. Latchman

Publikováno v: International journal of oncology. 10(6)

Brn-3a and Brn-3b are closely related members of the POU family of transcription factors which have opposite effects on the activity of target promoters. When mouse or human neuroblastoma cells are induced to differentiate to a non-dividing phenotype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b18748f55543040ae42b8098f9a480d
https://pubmed.ncbi.nlm.nih.gov/21533495

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Growth of herpes simplex virus and purification of viral DNA

Autor: D S, Latchman, L M, Kemp

Publikováno v: Methods in molecular biology (Clifton, N.J.). 8

In order to use herpes simplex virus (HSV) as a vector for the transmission and expression of foreign genes, it is obviously necessary to be able to prepare stocks of the virus and to propagate both HSV and the recombinant viruses derived from it. Si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fdf42e73c15f23717e00e74e59a6117a
https://pubmed.ncbi.nlm.nih.gov/21390712

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Herpes simplex virus life cycle and the design of viral vectors

Autor: D S, Latchman

Publikováno v: Methods in molecular biology (Clifton, N.J.). 8

Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are doublestranded DNA viruses with a genome size of 152 kbp. The genome consists of two unique regions, U(L) (long) and U(s) (short), flanked by repeated sequences (Fig. 1; for review, see ref.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5c1e089829203e0c183fec0814573b1
https://pubmed.ncbi.nlm.nih.gov/21390711

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HSV-Cellular Protein Interactions

Autor: D S, Latchman

Publikováno v: Methods in molecular medicine. 10

The herpes simplex virus (HSV) lytic cycle is dependent on a precise temporal pattern of viral gene expression with the initial expression of the immediate-early (IE) genes, followed by the early genes, and finally late gene expression (1). Although

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ebf2e6a534a2d6793807cbc7da1e444
https://pubmed.ncbi.nlm.nih.gov/21374235

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Transcriptional regulation of viral gene expression

Autor: D. S. Latchman

Publikováno v: Reviews in Medical Virology. 3:115-122

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0176b8db6dba5a4e22a0b257b231d50
https://doi.org/10.1002/rmv.1980030208

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Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters

Autor: D S Latchman, K A Lillycrop

Publikováno v: Journal of Biological Chemistry. 267:24960-24965

The RNA encoding the octamer-binding transcription factor Oct-2 is alternatively spliced in both neuronal cells and in B cells to yield multiple mRNAs encoding different isoforms of the protein. We show that, compared with B cells, neuronal cells ove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f06dfad1f480822ff39c04dc6c8e967
https://doi.org/10.1016/s0021-9258(19)73991-x

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The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activity

Autor: C L Dent, K A Lillycrop, J K Estridge, N S Thomas, D S Latchman

Publikováno v: Molecular and Cellular Biology. 11:3925-3930

B lymphocytes contain an octamer-binding transcription factor, Oct-2, that is absent in most other cell types and plays a critical role in the B-cell-specific transcription of the immunoglobulin genes. A neuronal form of this protein has also been de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff054f9ceb66da2cd5e1909c5fdbcc1b
https://doi.org/10.1128/mcb.11.8.3925

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Regulated Expression of the Small Nuclear Ribonucleoprotein Particle Protein SmN in Embryonic Stem Cell Differentiation

Autor: N G, Sharpe, D G, Williams, D S, Latchman

Publikováno v: Molecular and Cellular Biology. 10:6817-6820

The SmN protein is a component of small nuclear ribonucleoprotein particles and is closely related to the ubiquitous SmB and B' splicing proteins. It is expressed in a limited range of tissues and cell types, including several undifferentiated embryo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c88d0537800a74a543d86d9b79269e1
https://doi.org/10.1128/mcb.10.12.6817-6820.1990

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