Zobrazeno 1 - 10
of 31 867
pro vyhledávání: '"D. Rosen"'
Autor:
Wen-Jou Chang, Maria S. Baker, Eleonora Laritsky, Chathura J. Gunasekara, Uditha Maduranga, Justine C. Galliou, Joseph W. McFadden, Jessica R. Waltemyer, Bruce Berggren-Thomas, Brianna N. Tate, Hanxue Zhang, Benjamin D. Rosen, Curtis P. Van Tassell, George E. Liu, Cristian Coarfa, Yi Athena Ren, Robert A. Waterland
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background We recently identified ~ 10,000 correlated regions of systemic interindividual epigenetic variation (CoRSIVs) in the human genome. These methylation variants are amenable to population studies, as DNA methylation measurements in b
Externí odkaz:
https://doaj.org/article/d374279e13bb4fddb9705909460fcb20
Autor:
Fiona Fernando, Maria Sol Andres, Simone Claudiani, Nazanin Zounemat Kermani, Giulia Ceccarelli, Andrew J. Innes, Afzal Khan, Stuart D. Rosen, Jane F. Apperley, Alexander R. Lyon, Dragana Milojkovic
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Background The therapeutic landscape of chronic myeloid leukaemia (CML) has been transformed by tyrosine kinase inhibitors (TKI). Nilotinib, showed higher rates of major molecular response than imatinib, however associated with higher cardio
Externí odkaz:
https://doaj.org/article/f3fb29a7cf9b43e2b4d17bd6d64a0418
Autor:
P. M. Forster, C. Smith, T. Walsh, W. F. Lamb, R. Lamboll, B. Hall, M. Hauser, A. Ribes, D. Rosen, N. P. Gillett, M. D. Palmer, J. Rogelj, K. von Schuckmann, B. Trewin, M. Allen, R. Andrew, R. A. Betts, A. Borger, T. Boyer, J. A. Broersma, C. Buontempo, S. Burgess, C. Cagnazzo, L. Cheng, P. Friedlingstein, A. Gettelman, J. Gütschow, M. Ishii, S. Jenkins, X. Lan, C. Morice, J. Mühle, C. Kadow, J. Kennedy, R. E. Killick, P. B. Krummel, J. C. Minx, G. Myhre, V. Naik, G. P. Peters, A. Pirani, J. Pongratz, C.-F. Schleussner, S. I. Seneviratne, S. Szopa, P. Thorne, M. V. M. Kovilakam, E. Majamäki, J.-P. Jalkanen, M. van Marle, R. M. Hoesly, R. Rohde, D. Schumacher, G. van der Werf, R. Vose, K. Zickfeld, X. Zhang, V. Masson-Delmotte, P. Zhai
Publikováno v:
Earth System Science Data, Vol 16, Pp 2625-2658 (2024)
Intergovernmental Panel on Climate Change (IPCC) assessments are the trusted source of scientific evidence for climate negotiations taking place under the United Nations Framework Convention on Climate Change (UNFCCC). Evidence-based decision-making
Externí odkaz:
https://doaj.org/article/ef7ee21c7458401c81ff5b10b2209055
Autor:
Commins, Margaret M.
Publikováno v:
Latin American Politics and Society, 2016 Dec 01. 58(4), 168-171.
Externí odkaz:
https://www.jstor.org/stable/44683871
Autor:
Shuai Yan, Anna Santoro, Micah J. Niphakis, Antonio M. Pinto, Christopher L. Jacobs, Rasheed Ahmad, Radu M. Suciu, Bryan R. Fonslow, Rachel A. Herbst-Graham, Nhi Ngo, Cassandra L. Henry, Dylan M. Herbst, Alan Saghatelian, Barbara B. Kahn, Evan D. Rosen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Obesity-induced inflammation causes metabolic dysfunction, but the mechanisms remain elusive. Here we show that the innate immune transcription factor interferon regulatory factor (IRF3) adversely affects glucose homeostasis through inductio
Externí odkaz:
https://doaj.org/article/85b643d7bcf449cfb95b22f8c588eacb
Autor:
Frankie D. Heyward, Nan Liu, Christopher Jacobs, Natalia L. S. Machado, Rachael Ivison, Aykut Uner, Harini Srinivasan, Suraj J. Patel, Anton Gulko, Tyler Sermersheim, Linus Tsai, Evan D. Rosen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract AgRP neurons in the arcuate nucleus of the hypothalamus (ARC) coordinate homeostatic changes in appetite associated with fluctuations in food availability and leptin signaling. Identifying the relevant transcriptional regulatory pathways in
Externí odkaz:
https://doaj.org/article/cb1199e1ff5441d09265e83f4a574091
Autor:
Isabelle Senechal, Nikolaos Vogiatzakis, Maria Sol Andres, Jieli Tong, Sivatharshini Ramalingam, Stuart D Rosen, Alexander R Lyon, Muhummad Sohaib Nazir
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-5 (2024)
Abstract Panitumumab is a human immunoglobulin monoclonal antibody designed to target the epidermal growth factor receptor (EGFR) which is used in the treatment of metastatic colorectal cancer alone or in combination with chemotherapy. In this report
Externí odkaz:
https://doaj.org/article/79072bc4cdbc402b95547058e29b3e96
Autor:
Isabelle Senechal, Maria Sol Andres, Jieli Tong, Ylenia Perone, Sivatharshini Ramalingam, Muhummad Sohaib Nazir, Stuart D Rosen, Nicholas Turner, Alistair Ring, Alexander R Lyon
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-4 (2024)
Abstract Long-term anti-HER2 therapy in metastatic HER2 + cancers is increasing, but data about the incidence and risk factors for developing late Cancer therapy-related cardiac dysfunction (CTRCD) are missing. We conducted a single-centre, retrospec
Externí odkaz:
https://doaj.org/article/4db7df5b530f45faaf37f7685c5359dd
Autor:
Feinberg, Richard
Publikováno v:
Foreign Affairs, 2016 Jan 01. 95(1), 179-179.
Externí odkaz:
http://www.jstor.org/stable/43946664
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101948- (2024)
Objective: Uncoupling protein 1 (UCP1), a mitochondrial protein responsible for nonshivering thermogenesis in adipose tissue, serves as a distinct marker for thermogenic brown and beige adipocytes. Ucp1-Cre mice are thus widely used to genetically ma
Externí odkaz:
https://doaj.org/article/451aedb5b99c453696ea8af312e17cc0