Zobrazeno 1 - 10
of 116
pro vyhledávání: '"D. Raleigh"'
Autor:
Saadyah E. Averick, Andrew J. Kassick, Daihyun Song, Borui Zhang, Jennifer Vigliaturo, Diego Luengas, Pedro Silva-Ortiz, Marco Pravetoni, Michael D. Raleigh
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionFentanyl and fentanyl analogs (F/FA) have become increasingly common adulterants in counterfeit prescription pills and illicit street drug mixtures due to their ease of synthesis and exceedingly high potency. The ongoing epidemic of fatal
Externí odkaz:
https://doaj.org/article/86ed8107bf8a4408b5e7152bbfc265b8
Autor:
Michael D Raleigh, Nicola Beltraminelli, Stephanie Fallot, Mark G LeSage, Amy Saykao, Paul R Pentel, Steve Fuller, Thomas Thisted, Zuzanna Biesova, Stephen Horrigan, Darryl Sampey, Bin Zhou, Matthew W Kalnik
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254247 (2021)
Use of nicotine-specific monoclonal antibodies (mAbs) to sequester and reduce nicotine distribution to brain has been proposed as a therapeutic approach to treat nicotine addiction (the basis of tobacco use disorder). A series of monoclonal antibodie
Externí odkaz:
https://doaj.org/article/20970bf6715646829279dd4d4d1ec7c3
Autor:
Carly Baehr, Andrew J. Kassick, Jennifer Vigliaturo, Diego Luengas, Aaron Khaimraj, Marco Pravetoni, Saadyah E. Averick, Michael D. Raleigh
Publikováno v:
ACS Chemical Neuroscience. 14:1291-1298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f42e73b4c6ff06b4995054e9aa0ed8
https://doi.org/10.1021/acschemneuro.2c00797
https://doi.org/10.1021/acschemneuro.2c00797
Autor:
Paul R. Pentel, Michael D. Raleigh, Mark G. LeSage, Thomas Thisted, Stephen Horrigan, Zuzana Biesova, Matthew W. Kalnik
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background The bacterial nicotine-degrading enzyme NicA2 isolated from P. putida was studied to assess its potential use in the treatment of tobacco dependence. Results Rats were pretreated with varying i.v. doses of NicA2, followed by i.v.
Externí odkaz:
https://doaj.org/article/a0e3cd1965a54648bfdb8c93d6f253a0
Autor:
Fatima A. Hamid, Cheryl L. Marker, Michael D. Raleigh, Aaron Khaimraj, Scott Winston, Paul R. Pentel, Marco Pravetoni
Publikováno v:
Vaccine
Opioid use disorders (OUD) and overdose represent a public health threat, resulting in thousands of deaths annually worldwide. Vaccines offer a promising treatment for OUD and potentially the prevention of fatal overdoses. The Oxy(Gly)(4)-sKLH Conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e951423e6998ceef859e9e729ee7d42f
https://doi.org/10.1016/j.vaccine.2022.03.053
https://doi.org/10.1016/j.vaccine.2022.03.053
Covalently Loaded Naloxone Nanoparticles as a Long-Acting Medical Countermeasure to Opioid Poisoning
Autor:
Michael D. Raleigh, Toby L. Nelson, Saadyah Averick, Mohammad Ebqa'Ai, Diego Luengas, Mariah Wu, Nestor D. Tomycz, Andrew J. Kassick, Marco Pravetoni, L. P. Tharika Nirmani
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] The mu opioid receptor antagonist naloxone has been a vital, long-standing countermeasure in the ongoing battle against opioid use disorders (OUD) and toxicity. However, due to its distinctive short elimination half-life, naloxone h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcc25b1d4f9c95bcd0f86777c0fd722
https://doi.org/10.1021/acsptsci.1c00168
https://doi.org/10.1021/acsptsci.1c00168
Autor:
M D Raleigh, S J Peterson, M Laudenbach, F Baruffaldi, F I Carroll, S D Comer, H A Navarro, T L Langston, S P Runyon, S Winston, M Pravetoni, P R Pentel
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0184876 (2017)
Among vaccines aimed at treating substance use disorders, those targeting opioids present several unique medication development challenges. 1) Opioid overdose is a common complication of abuse, so it is desirable for an opioid vaccine to block the to
Externí odkaz:
https://doaj.org/article/3b2e7ab5a7434204b22b8fab42f5d495
Akademický článek
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Akademický článek
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Autor:
H. Vasudevan, C. Delley, A. Aabedi, M.P. Nguyen, R.A. Morshed, J.S. Young, B. Demaree, D. Diwanji, S. Hervey-Jumper, L. Boreta, S.E. Fogh, J.L. Nakamura, P.V. Theodosopoulos, J. Phillips, M. Daras, K. Tsai, P.K. Sneed, M.K. Aghi, D. Raleigh, S.E. Braunstein, A.R. Abate
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 114:e63-e64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1299a3909ca65b8a45682df0b53bc83b
https://doi.org/10.1016/j.ijrobp.2022.07.813
https://doi.org/10.1016/j.ijrobp.2022.07.813