Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D. R. Safina"'
Publikováno v:
Успехи молекулярной онкологии, Vol 5, Iss 2, Pp 42-49 (2018)
Background. Therapy with compounds potentially capable to block KRAS oncogene signaling pathway is perspective direction in modern oncopharmacology. The aim of current study was to investigate effects of the combined treatment with rapamycin (RAP) an
Externí odkaz:
https://doaj.org/article/05e2030750514e4081e81eac6096520a
Publikováno v:
Тонкие химические технологии, Vol 6, Iss 2, Pp 51-57 (2011)
The genes of nerve growth factor (NGF), brain neurotrophic factor (BDNF) and human neurotrophic factor 3 (NT-3) were cloned and expressed in Escherichia coli. Methods of purification and renaturation of the proneurotrophins were developed. It was sho
Externí odkaz:
https://doaj.org/article/8bd93c2ec3b84897b8b0bc509ebac3bd
Autor:
E. D. Sverdlov, D. R. Safina, Sergey V. Kostrov, L. G. Kondratyeva, Igor P. Chernov, E. P. Kopantzev
Publikováno v:
Cancer Management and Research. 11:7077-7087
Background: In cancer biology, metastasizing is one of the most poorly studied processes. Pancreatic ductal adenocarcinoma (PDAC) is characterized by early metastasis, which is the leading cause of death. The PDX1 protein is crucial for the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267318c7ec7f14738bd5732d73325ce1
https://doi.org/10.2147/cmar.s209940
https://doi.org/10.2147/cmar.s209940
Autor:
Sergey V. Kostrov, Ilya V. Demidyuk, Eugene D. Sverdlov, Maria A. Karaseva, D. R. Safina, Alexey A. Komissarov, Polina I. Selina, Marina P. Roschina
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0232045 (2020)
PLoS ONE, Vol 15, Iss 4, p e0232045 (2020)
The functional efficiency of the expression cassettes integrated into a plasmid and a PCR- amplified fragment was comparatively analyzed after transient transfection in vitro or introduction into the developing embryo of Danio rerio. The cassettes co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bc1a674d9b6782f2f8b9b848eacd97
https://pubmed.ncbi.nlm.nih.gov/32330156
https://pubmed.ncbi.nlm.nih.gov/32330156
Publikováno v:
Acta Naturae. 10:24-29
Development and implementation of adequate organism-level models is one of the key elements in biomedical research that focuses on experimental oncology. Over the last decade, studies using Zebrafish (Danio rerio) have gained in popularity in this ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00ec8f876654c2ead07d82310710a1e7
https://doi.org/10.32607/20758251-2018-10-2-24-29
https://doi.org/10.32607/20758251-2018-10-2-24-29
Autor:
O. V. Dolotov, E. S. Manuilova, Igor A. Grivennikov, A G Kobylyansky, D R Safina, S A Antonov
Publikováno v:
Bulletin of Experimental Biology and Medicine. 162:679-683
The cholinergic, GABAergic, and catecholaminergic neurons derived from mouse embryonic stem cells in a culture medium supplemented with recombinant NGF were phenotyped and scored. NGF stimulated generation of neurons, but not neuronal progenitors fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b475bbfd7f1850fee1464d0128355b31
https://doi.org/10.1007/s10517-017-3686-1
https://doi.org/10.1007/s10517-017-3686-1
Publikováno v:
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 121:107
The review highlights the current understanding of the role of autoimmune neuroinflammation in the pathogenesis of vascular, neurodegenerative and other diseases of the nervous system. The mechanisms of the response of the resident cells of the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d915b44cc8b95c9b4c0907dd0d92f7a
https://doi.org/10.17116/jnevro2021121041107
https://doi.org/10.17116/jnevro2021121041107
Autor:
O. P. Bednova, Demkin Vv, Ilya V. Demidyuk, Maria A. Karaseva, D. R. Safina, Alexey A. Komissarov, A. A. Kazakov, Marina P. Roschina
Publikováno v:
Molecular Genetics, Microbiology and Virology. 31:156-162
Comparative evaluation of transgene expression efficiency provided by genetic constructs of different structures is an important stage in the development of new and optimization of existing expression vectors. However, there is no universal approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4888379856f10a60d7c8748e8c899f66
https://doi.org/10.3103/s0891416816030058
https://doi.org/10.3103/s0891416816030058
Publikováno v:
Acta Naturae
Development and implementation of adequate organism-level models is one of the key elements in biomedical research that focuses on experimental oncology. Over the last decade, studies using Zebrafish (Danio rerio) have gained in popularity in this ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97964f10c5ada0f653d781697aa83d54
https://pubmed.ncbi.nlm.nih.gov/30116612
https://pubmed.ncbi.nlm.nih.gov/30116612
Publikováno v:
Journal of Neuroscience Research. 93:1865-1873
Neurotrophin-3 (NT-3) belongs to the family of highly conserved dimeric growth factors that controls the differentiation and activity of various neuronal populations. Mammals contain both the mature (NT-3) and the precursor (pro-NT-3) forms of neurot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dcaee5477021def56c1751e640d8262
https://doi.org/10.1002/jnr.23667
https://doi.org/10.1002/jnr.23667