Výsledky vyhledávání - "D. R. MORTON"

Metabolism of leukotriene A4 by human erythrocytes. A novel cellular source of leukotriene B4

Autor: Bengt Samuelsson, D. R. Morton, Frank A. Fitzpatrick, J E McGee, W F Liggett, S Bunting

Publikováno v: Journal of Biological Chemistry. 259:11403-11407

Human erythrocytes transformed leukotriene A4 into leukotriene B4. Metabolism was proportional to the erythrocyte concentration, even at subphysiological levels (0.08-4 X 10(9) erythrocytes/ml). Comparative metabolic studies excluded the possibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0e2a59159f498d78a022cf3bf14c3e0
https://doi.org/10.1016/s0021-9258(18)90875-6

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Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis and cyclic AMP accumulation in human polymorphonuclear leukocytes

Autor: R R, Gorman, D R, Morton, N K, Hopkins, A H, Lin

Publikováno v: Advances in prostaglandin, thromboxane, and leukotriene research. 12

Both LTB4 and AGEPC stimulate PMN aggregation in a concentration-dependent manner. The lipoxygenase inhibitors ETYA and NDGA block AGEPC-induced but not LTB4-induced PMN aggregation. Agents that elevate PMN cyclic AMP levels block both LTB4-and AGEPC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7953c719fbf68ed710c313656ca208b3
https://pubmed.ncbi.nlm.nih.gov/6303092

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Neuronal cell bodies in the hypothalamic paraventricular nucleus mediate stress-induced renin and corticosterone secretion

Autor: K. D. R. Morton, C L Bethea, L.D. Van de Kar, M. S. Brownfield

Publikováno v: Neuroendocrinology. 50(1)

The present studies were undertaken to determine the involvement of neurons in the hypothalamic paraventricular nucleus (PVN) in stress-induced renin secretion. The stressor was a 10-min conditioned emotional response (CER) paradigm. Bilateral electr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b381f3556771b3e86848cd809c6b9799
https://pubmed.ncbi.nlm.nih.gov/2666872

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Inhibition of rat liver glutathione S-transferases by piriprost: kinetics of the inhibition and preliminary evidence that piriprost may be a poor alternative substrate for these enzymes

Autor: M K, Bach, J, O'Brien, J R, Brashler, M A, Johnson, D R, Morton

Publikováno v: Research communications in chemical pathology and pharmacology. 49(3)

The administration of tritiated piriprost, an inhibitor of leukotriene formation, to rats resulted in its rapid excretion. Some 90 percent of the initial dose was excreted in the feces and only five to six percent were recovered in the urine, regardl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24e457bcb92d2873c03f431c1d9b4c9f
https://pubmed.ncbi.nlm.nih.gov/3903894

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