Zobrazeno 1 - 10
of 10
pro vyhledávání: '"D. R. KLONNE"'
Autor:
B, Ballantyne, J C, Norris, D E, Dodd, D R, Klonne, P E, Losco, D A, Neptun, S C, Price, P, Grasso
Publikováno v:
Journal of applied toxicology : JAT. 17(4)
5-Ethylidene-2-norbornene (ENB) is an industrial chemical whose physical properties indicate a likelihood for vapor exposure to humans. The potential for target organ or cumulative toxicity was investigated in rats exposed for 6 h per day for 9 days
Publikováno v:
Journal of applied toxicology : JAT. 17(4)
The acute toxicity and primary irritancy of the industrial chemicals 5-ethylidene-2-norbornene (ENB) and 5-vinyl-2-norbornene (VNB) were studied. They are of moderate acute peroral toxicity in the rat, with LD50 values for ENB of 2.54 (male) and 5.66
Publikováno v:
Journal of applied toxicology : JAT. 16(6)
Timed-pregnant Fischer 344 rats were exposed whole body to N,N-dimethylethanolamine vapor for 6 h per day on gestational days 6-15 at mean (+/- SD) analytically measured concentrations of 10.4 +/- 0.86, 29.8 +/- 2.14 and 100 +/- 4.9 ppm. Dams were sa
Publikováno v:
Toxicological Sciences. 9:557-572
Publikováno v:
Fundamental and Applied Toxicology. 8:170-178
n-Butyl mercaptan (n-BM) is used as a solvent and a chemical intermediate. Pregnant Charles River CD-1 mice and COBS CD rats were randomly assigned to a control group and to three n-BM-exposed groups of 25 rats and 25 mice each. The animals were expo
Publikováno v:
Fundamental and Applied Toxicology. 9:557-572
Chlorine (Cl2) gas is a potentially lung-damaging irritant which is used in the chemical, plastics, and paper industries. There are no data published using experimental animals on the chronic inhalation toxicity of chlorine. The purpose of this study
Autor:
D R Johnson, D R Klonne
Publikováno v:
Journal of toxicology and environmental health. 16(1)
Previous studies from this laboratory have indicated that dithiothreitol (DTT) administration (31 mg DTT/kg, i.p.) 1 h after mercuric chloride injection (3 mg/kg, i.v.) results in partial reversal of Hg-induced renal toxicity without altering total r
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 12(2)
Timed pregnant Fischer 344 rats and New Zealand White rabbits were exposed to vapor from ethylene glycol monohexyl ether (EGHE, CAS No. 112-25-4) for 6 hr/day on gestational days (gd) 6 through gd 15 (rats) or gd 6 through gd 18 (rabbits) at analytic
Publikováno v:
Veterinary and human toxicology. 27(6)
2-Ethyl-1,3-hexanediol (EHD), an insect repellant, was found to have acute peroral LD50 values in the rat of 9.85 ml/kg (males) and 4.92 ml/kg (females). Acute percutaneous LD50 values in the rabbit were 10.8 ml/kg (males) and 9.51 ml/kg (females). T
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 9(3)
Chlorine (Cl2) gas is a potentially lung-damaging irritant which is used in the chemical, plastics, and paper industries. There are no data published using experimental animals on the chronic inhalation toxicity of chlorine. The purpose of this study