Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D. R. Cool"'
Autor:
Haley E. Melikian, Randy D. Blakely, Vadivel Ganapathy, F. H. Leibach, Sammanda Ramamoorthy, Virendra B. Mahesh, D. R. Cool
Publikováno v:
Journal of Biological Chemistry. 268:21626-21631
Treatment of confluent cultures of JAR human placental choriocarcinoma cells with cholera toxin or forskolin for 16 h markedly stimulated (2.4-fold) serotonin transport activity in these cells. Cycloheximide, an inhibitor of protein synthesis or acti
Publikováno v:
Current Eye Research. 12:29-36
The characteristics of taurine transport were studied in a human retinal pigment epithelial cell line (HRPE). Uptake of taurine into monolayer cultures of the HRPE cells was markedly stimulated by the presence of NaCl in the uptake medium whereas the
Publikováno v:
Biochemical Journal. 286:89-95
The 5-hydroxytryptamine (5-HT; serotonin) transporter was solubilized from purified human placental brush border membranes by cholate in the presence of urea, and the solubilized transporter was reconstituted into proteoliposomes in a functionally ac
Publikováno v:
Journal of Biological Chemistry. 266:15750-15757
The JAR human placental choriocarcinoma cell line transports serotonin, accumulating the monoamine inside the cell against a concentration gradient. The transport is energized by an NaCl gradient. Tricyclic (imipramine and desipramine) and non-tricyc
Autor:
Virendra B. Mahesh, Palaniappan Kulanthaivel, V. Ganapathy, D. R. Cool, F. H. Leibach, Sammanda Ramamoorthy
Publikováno v:
Biochemical Journal. 277:53-58
The JAR human placental choriocarcinoma cell line transports taurine, concentrating it over 1000-fold inside the cell. The transport system is energized by a Na+ gradient and exhibits an absolute requirement for Cl-. Neutral beta-amino acids such as
Publikováno v:
Biochemical Pharmacology. 40:2161-2167
The interaction of fluoxetine, a non-tricyclic antidepressant, with the human placental serotonin transporter was investigated by studying its influence on [3H]paroxetine binding to the transporter and on [3H]serotonin uptake via the transporter. The
Publikováno v:
Biochemistry. 29:1818-1822
The modulation of serotonin uptake kinetics by Na+, Cl-, H+, and K+ was investigated in brush-border membrane vesicles prepared from normal human term placentas. The presence of Na+ and Cl- in the external medium was mandatory for the function of the
Publikováno v:
Journal of Burn Care & Rehabilitation. 11:14-20
A copper slug heated with a soldering iron was used to produce full- and partial-thickness burns on the backs of mice. The untreated partial-thickness burns healed by outgrowth of epidermal cells from the hair follicles and adjoining skin, and the fu
Publikováno v:
Trends in endocrinology and metabolism: TEM. 8(4)
Peptide hormones, neuropeptides, and other molecules such as the granins are specifically packaged into granules of the regulated secretory pathway and released in a calcium-dependent manner upon stimulation. Many of these molecules are synthesized a
Publikováno v:
Endocrinology. 137(12)
The subcellular localization and functionality of transfected yeast aspartic protease 3 (YAP3p) in a mammalian cell line were investigated. The complementary DNAs encoding the prohormone-processing enzyme (YAP3p) and a prohormone, bovine POMC, were c