Zobrazeno 1 - 9 of 9 pro vyhledávání: '"D. R. Britton"'
2
Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration
Autor: J. Williams, D. Kerkman, Peter Curzon, D. R. Britton, R. G. MacKenzie, J. W. Kebabian
Publikováno v: Pharmacology Biochemistry and Behavior. 39:911-915
Rats trained to self-administer cocaine (0.75 mg/kg/infusion) on an FR-5 schedule were treated with selective D1 or D2 antagonists. A69045, a D1 antagonist with no appreciable affinity for 5-HT receptors increased cocaine self-administration to 147,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334e36432aab843d7edea4132203ee49
https://doi.org/10.1016/0091-3057(91)90052-4
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3
A68930: A Potent and Specific Agonist for the D-1 Dopamine Receptor
Autor: K. Asin, R. G. MacKenzie, R. Schoenleber, M. DeNinno, J. F. McKelvy, C. Briggs, D. R. Britton, J. W. Kebabian
Publikováno v: American Journal of Hypertension. 3:40S-42S
A68930 (5,6-dihydroxy-3-phenyl-1-aminomethyl-isochroman) is a potent (EC50 = 2.5 nmol/L) partial agonist at the D-1 dopamine receptor. In contrast, A68930 is a much weaker agonist (EC50 = 3,920 nmol/L) at the D-2 dopamine receptor. The orientation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e42363028cd68cbfb9680abcc3714b
https://doi.org/10.1093/ajh/3.6.40s
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4
Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636
Autor: C W, Lin, B R, Bianchi, T R, Miller, M A, Stashko, S S, Wang, P, Curzon, L, Bednarz, K E, Asin, D R, Britton
Publikováno v: The Journal of pharmacology and experimental therapeutics. 276(3)
A-77636 is a dopamine (DA) D1 receptor-selective agonist that was previously shown to elicit beneficial responses in animal models of Parkinson's disease (PD) (Kebabian et al.: Eur. J. Pharmacol. 229: 203, 1992). However, A-77636 is of limited potent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab561fabbb24dc8d89a53e6066319237
https://pubmed.ncbi.nlm.nih.gov/8786531
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5
ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease
Autor: K, Shiosaki, P, Jenner, K E, Asin, D R, Britton, C W, Lin, M, Michaelides, L, Smith, B, Bianchi, S, Didomenico, L, Hodges, Y, Hong, L, Mahan, J, Mikusa, T, Miller, A, Nikkel, M, Stashko, D, Witte, M, Williams
Publikováno v: The Journal of pharmacology and experimental therapeutics. 276(1)
(-)-Trans 9,10-hydroxy-2-propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5- azacyclopent-1-ena[c]phenanthrene hydrochloride (A-86929) is a potent and selective full agonist at the dopamine (DA) D1-like receptor. Judging by its binding affinities to the D1 and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d7990b615b311ccdc2a82d01eb99de2
https://pubmed.ncbi.nlm.nih.gov/8558425
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6
Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys
Autor: P, Blanchet, P J, Bédard, D R, Britton, J W, Kebabian
Publikováno v: The Journal of pharmacology and experimental therapeutics. 267(1)
The motor effects of selective D-1 dopamine receptor stimulation in Parkinson's disease have been explored in a limited number of studies with partial D-1 agonists only and the results were unsatisfactory. Four 1-methyl-4-phenyl-1,2,3,6-tetrahydropyr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::160904ba1a75645623ceb0bbfce79267
https://pubmed.ncbi.nlm.nih.gov/7901395
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7
Clinical Pharmacokinetics of Selected Psychotropic Drugs
Autor: Z. S. El-Wardany, J. R. Bianchine, C. P. Brown, D. R. Britton
Publikováno v: Handbook of Psychopharmacology ISBN: 9781468431919
The study of pharmacokinetics is intended to provide information about the dynamics of the various factors which determine the proportion of a given dose of a drug which will become available at specific receptor sites to produce a therapeutic or a t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcedd1f4547801df7326813874ea48b2
https://doi.org/10.1007/978-1-4684-3189-6_5
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