Zobrazeno 1 - 10
of 46
pro vyhledávání: '"D. Quiggle"'
Publikováno v:
Chirality. 16:379-387
Information about the potential and extent of bioinversion of chiral drugs in laboratory animal species and humans is critical to the interpretation of preclinical pharm-tox studies with these drugs. Unlike in the dog, guinea pig, and rabbit, in huma
Publikováno v:
InflammoPharmacology. 8:189-206
R-flurbiprofen, the non-COX inhibiting enantiomer of the non-steroidal antiinflammatory (NSAI) agent R-, S-flurbiprofen has proved to have a pharmacology independent of the S-enantiomer. In this presentation, we recount its anti-proliferative activit
Autor:
Karina M. Gibson, E. David Murray, John D. Mccracken, Darko Kantoci, Douglas D. Leipold, David D. Quiggle, William J. Wechter
Publikováno v:
Life Sciences. 66:745-753
Our previous studies with the mouse model of familial adenomatous polyposis (FAP), C57BL/6J-APCMin/+ or Min mouse, demonstrated the optimal dose for adenoma reduction with R-flurbiprofen was 10 mg/kg/day as an undivided dose. Divided doses exhibited
Autor:
E. David Murray, Youjiang Liu, Darko Kantoci, Resa L. Chase, David D. Quiggle, William J. Wechter, John D. Mccracken, Yoshimitzu Mineyama
Publikováno v:
The Journal of Clinical Pharmacology. 36:540-545
Nonsteroidal antiinflammatory drugs (NSAIDs) are recognized for inhibiting growth of colon tumors in animal models, and for reducing the risk of colon cancer in humans. The mechanisms involved have not been established, but are thought to be related
Autor:
James D. Quiggle
The premise of Why Christians Should Not Tithe is simple: God, having freed his people from the Law through faith in Jesus Christ, does not place on them a burden from the Law. The thesis is equally as simple: Christian giving is not a tithe. Christ
Autor:
W J, Wechter, D D, Leipold, E D, Murray, D, Quiggle, J D, McCracken, R S, Barrios, N M, Greenberg
Publikováno v:
Cancer research. 60(8)
E-7869 (R-flurbiprofen) is a single enantiomer of a racemic nonsteroidal anti-inflammatory drug. E-7869 does not inhibit either cyclooxygenase-1 or cyclooxygenase-2. We used the transgenic adenocarcinoma mouse prostate (TRAMP) mouse, a prostate cance
Autor:
James D. Quiggle
The Epistle of Jesus to the Church is a commentary on the book of Revelation that assumes Jesus was the author and John the reporter of the words and events described. Here one will not find an explanation of an anti-Roman message written by John in
Autor:
W J, Wechter, D, Kantoci, E D, Murray, D D, Quiggle, D D, Leipold, K M, Gibson, J D, McCracken
Publikováno v:
Cancer research. 57(19)
We used the C57BL/6J-APC(Min)/+ mouse (Min mouse) to evaluate the chemopreventive effects of R-flurbiprofen (R-FB), the noncyclooxygenase-inhibiting enantiomer of FB. Weanling Min mice were administered 6 weeks of oral treatment with R-FB using 2.5-2
Autor:
E D, Murray, W J, Wechter, D, Kantoci, W H, Wang, T, Pham, D D, Quiggle, K M, Gibson, D, Leipold, B M, Anner
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(2)
The structural elucidation and mechanism of action of a potential component, LLU-alpha, of what is possibly a multifactorial complex known as "natriuretic hormone" was recently reported [Wechter, W.J. et al. (1996a) Proc. Natl. Acad. Sci. U.S.A. 93:
Publikováno v:
Industrial & Engineering Chemistry. 39:1322-1328