Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D. Q. Brown"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 22(6)
This study investigated the metabolism of the radio- and chemoprotector compound, WR-2721 [amifostine; s-2-(3- aminopropylamino)ethylphosphorothioate], in the Balb/c mouse. The latter was selected for these studies because considerable radiation prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fddd801e438f4533ba1f972d1dcb1ac8
https://pubmed.ncbi.nlm.nih.gov/7895607
https://pubmed.ncbi.nlm.nih.gov/7895607
Autor:
E. L. Engelhardt, Matthew C. Fenning, C. C. Stobbe, Shimon Gatt, J. Donald Chapman, D. Q. Brown, Arie Dagan
Publikováno v:
SPIE Proceedings.
The treatment of solid human tumors of volume up to 50 cm3 will require significant gains in photosensitizing effect over that obtained with Photofrin and 630 nm light. Some techniques of interstitial radioisotope brachytherapy can be exploited for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28bc3564536f377cdd391d7f40f7594e
https://doi.org/10.1117/12.179975
https://doi.org/10.1117/12.179975
Publikováno v:
Cancer. 32:541-546
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0ca7ce68c988a81e3c284707288b09
https://doi.org/10.1002/1097-0142(197309)32:3<541::aid-cncr2820320305>3.0.co
https://doi.org/10.1002/1097-0142(197309)32:3<541::aid-cncr2820320305>3.0.co
Publikováno v:
Radiology. 163(1)
Photodynamic therapy relies on uptake of a photosensitizer (hematoporphyrin derivative [HpD]) by tumor cells and subsequent interaction of the photosensitizer with penetrating light. This technique has been applied in multiple animal systems and seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefd78cc139706819919cac077c3ac81
https://pubmed.ncbi.nlm.nih.gov/3823432
https://pubmed.ncbi.nlm.nih.gov/3823432
Autor:
H Katz, G J Broder, R Brookland, P J Moldofsky, Paul F. Engstrom, Lawrence R. Coia, M P Richter, Robert A. Gatenby, D Q Brown
Publikováno v:
Radiology. 156(1)
The role of oxygen in tumor response to therapy has been studied for several decades. We describe a technique that allows in vivo measurement of oxygen in tumors using computed tomography to guide probes. In the evaluation of 16 tumors, oxygen tensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda3358b5e777e5e31d1ebe41fa65f60
https://pubmed.ncbi.nlm.nih.gov/4001408
https://pubmed.ncbi.nlm.nih.gov/4001408
Publikováno v:
Radiation research. 109(1)
A study of the dephosphorylation of WR2721 by broken cell preparations of mouse liver revealed the presence of at least two distinctive activities. One activity was inactivated by heat treatment and was present in the nuclear and microsomal fractions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3499cd6ebe23e21313656ae8da150620
https://pubmed.ncbi.nlm.nih.gov/3027739
https://pubmed.ncbi.nlm.nih.gov/3027739
Publikováno v:
NCI monographs : a publication of the National Cancer Institute. (6)
The effectiveness of fractionated total body irradiation (TBI) in treatment of non-Hodgkin's lymphoma is limited by bone marrow toxicity. Because WR-2721 effectively protects bone marrow, we tested its potential in treatment of I-347 lymphoma in BALB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0927667a5ae3fe9bc5812c0ab270d25c
https://pubmed.ncbi.nlm.nih.gov/2832762
https://pubmed.ncbi.nlm.nih.gov/2832762
Publikováno v:
Cancer research. 37(10)
An assay has been developed to measure the ability of human lymphocytes to repair damage to DNA. In this assay, purified human lymphocytes are exposed to graded doses of radiation and then stimulated with phytohemagglutinin to undergo DNA replication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21517ef7576c15ee1394394cb839a94d
https://pubmed.ncbi.nlm.nih.gov/908009
https://pubmed.ncbi.nlm.nih.gov/908009
Publikováno v:
Research communications in chemical pathology and pharmacology. 6(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1cc6d9bccd10062af80806a897778c7
https://pubmed.ncbi.nlm.nih.gov/4760899
https://pubmed.ncbi.nlm.nih.gov/4760899
Autor:
L G, Christophoru, M E, Abu-Zeid, R P, Blaunstein, D Q, Brown, J F, Burns, A E, Carter, J G, Carter, R N, Compton, J T, Cox, F J, Davis
Publikováno v:
ORNL. U.S. Atomic Energy Commission.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10fadc7b6f252b5c4f7dffbd393ef4b3
https://pubmed.ncbi.nlm.nih.gov/5597974
https://pubmed.ncbi.nlm.nih.gov/5597974