Zobrazeno 1 - 10
of 841
pro vyhledávání: '"D. Putnam"'
Autor:
Matthew D. Putnam, MD, Andrew Rau, MS, PE, Michael Frohbergh, PhD, Kevin Ong, PhD, PE, Michael Bushelow, MS, Michael Blauth, MD
Publikováno v:
OTA International, Vol 6, Iss 2S (2023)
Background:. Femoral neck fracture displacement with subsequent vascular disruption is one of the factors that contribute to trauma-induced avascular necrosis of the femoral head. Iatrogenic damage of the intraosseous arterial system during fixation
Externí odkaz:
https://doaj.org/article/e8d0cb0fd551418882e07e23135a307f
Autor:
Felipe A. Calil, Bin-Zhong Li, Kendall A. Torres, Katarina Nguyen, Nikki Bowen, Christopher D. Putnam, Richard D. Kolodner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Defects in DNA mismatch repair (MMR) have been linked to inherited and sporadic cancers. Here the authors demonstrate that the DNA repair protein Rad27 (human FEN1) functions in one of three redundant mispair excision pathways, where its flap endonuc
Externí odkaz:
https://doaj.org/article/edd8c42e20fe4ec2a4fcf1e024649b17
Autor:
Anna K. Miller, Guogen Mao, Breanna G. Knicely, Hannah G. Daniels, Christine Rahal, Christopher D. Putnam, Richard D. Kolodner, Eva M. Goellner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
DNA mismatch repair (MMR) repairs replication errors, and MMR defects play a role in both inherited cancer predisposition syndromes and in sporadic cancers. MMR also recognizes mispairs caused by environmental and chemotherapeutic agents; however, in
Externí odkaz:
https://doaj.org/article/bfb164c88c9b4e268af71739856dca78
Drawing on collaborative research from a distinguished team at Harvard and Manchester universities, The age of Obama asks how two very different societies are responding to the tide of diversity that is being felt around the rich world. Guardian jour
Autor:
Lori Broderick, Shawn Yost, Dong Li, Matthew D. McGeough, Laela M. Booshehri, Marisela Guaderrama, Susannah D. Brydges, Karolina Kucharova, Niraj C. Patel, Margaret Harr, Hakon Hakonarson, Elaine Zackai, Ian G. Cowell, Caroline A. Austin, Boris Hügle, Corinna Gebauer, Jianguo Zhang, Xun Xu, Jian Wang, Ben A. Croker, Kelly A. Frazer, Christopher D. Putnam, Hal M. Hoffman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Topoisomerases are required to release topological stress on DNA during replication and transcription. Here, Broderick et al. report genetic variants in TOP2B that cause a syndromic B cell immunodeficiency associated with reduced TOP2B function, defe
Externí odkaz:
https://doaj.org/article/f68d775e267842bf9a3e97c19180cf33
Autor:
Florian Hoss, James L. Mueller, Francisca Rojas Ringeling, Juan F. Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D. Putnam, Richard D. Kolodner, Stefan Canzar, Matthias Geyer, Hal M. Hoffman, Eicke Latz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Leucine-rich repeat (LRR) domains are commonly present in immune regulatory proteins. Here the authors show that LRR exonic modularity and alternative splicing of an LRR-containing protein, NLRP3, modulate the ratio of functional/afunctional NLRP3 is
Externí odkaz:
https://doaj.org/article/e8556fbf0c984427a366f6b71e4114ec
Autor:
Hannah L. Klein, Giedrė Bačinskaja, Jun Che, Anais Cheblal, Rajula Elango, Anastasiya Epshtein, Devon M. Fitzgerald, Belén Gómez-González, Sharik R. Khan, Sandeep Kumar, Bryan A. Leland, Léa Marie, Qian Mei, Judith Miné-Hattab, Alicja Piotrowska, Erica J. Polleys, Christopher D. Putnam, Elina A. Radchenko, Anissia Ait Saada, Cynthia J. Sakofsky, Eun Yong Shim, Mathew Stracy, Jun Xia, Zhenxin Yan, Yi Yin, Andrés Aguilera, Juan Lucas Argueso, Catherine H. Freudenreich, Susan M. Gasser, Dmitry A. Gordenin, James E. Haber, Grzegorz Ira, Sue Jinks-Robertson, Megan C. King, Richard D. Kolodner, Andrei Kuzminov, Sarah AE Lambert, Sang Eun Lee, Kyle M. Miller, Sergei M. Mirkin, Thomas D. Petes, Susan M. Rosenberg, Rodney Rothstein, Lorraine S. Symington, Pawel Zawadzki, Nayun Kim, Michael Lisby, Anna Malkova
Publikováno v:
Microbial Cell, Vol 6, Iss 1, Pp 1-64 (2019)
Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily
Externí odkaz:
https://doaj.org/article/9deb4e4edc524ec78e599b9f614eaef3
Publikováno v:
eLife, Vol 9 (2020)
Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback inve
Externí odkaz:
https://doaj.org/article/efeba681793c43fb9973f17eae8a0e34
Autor:
Anjana Srivatsan, Bin-Zhong Li, Barnabas Szakal, Dana Branzei, Christopher D. Putnam, Richard D. Kolodner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
SWR-C and its substrate the histone variant Htz1 are considered important for genome maintenance. Here the authors reveal that SWR-C/Htz1 plays a critical role during replication stress caused by absence of the replication fork progression proteins M
Externí odkaz:
https://doaj.org/article/26b3c91b973843c4a9d010d3be601fc1
Publikováno v:
British Journal of Oral and Maxillofacial Surgery. 61:183-185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e62cb42e9fabcd5f23000829768b47e
https://doi.org/10.1016/j.bjoms.2022.12.011
https://doi.org/10.1016/j.bjoms.2022.12.011