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Imidazoleacetic Acid, a γ-Aminobutyric Acid Receptor Agonist, Can Be Formed in Rat Brain by Oxidation of Histamine

Publikováno v: Journal of Neurochemistry. 65:818-826

It is generally accepted that in mammalian brain histamine is metabolized solely by histamine methyltransferase (HMT), to form tele-methylhistamine, then oxidized to tele-methylimidazoleacetic acid. However, histamine's oxidative metabolite in the pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6c6cbcc97198522c0a5126e92f358e
https://doi.org/10.1046/j.1471-4159.1995.65020818.x

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Disposition of Histamine, Its Metabolites, and pros-Methylimidazoleacetic Acid in Brain Regions of Rats Chronically Infused with α-Fluoromethylhistidine

Autor: Erwin Douyon, Albert Marcus Morrishow, William F. Sawyer, George D. Prell

Publikováno v: Journal of Neurochemistry. 66:2153-2159

In mammalian brain, histamine is known to be metabolized solely by histamine methyltransferase (HMT), forming tele-methylhistamine (t-MH), then tele-methylimidazoleacetic acid (t-MIAA). We previously showed that imidazoleacetic acid (IAA), a GABA ago

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243703ba96e18fb0d2205c6c9701f250
https://doi.org/10.1046/j.1471-4159.1996.66052153.x

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Inhibitors of Histamine Methylation in Brain Promote Formation of Imidazoleacetic Acid, Which Interacts with GABA Receptors

Autor: Wah S. Lee, Erwin Duoyon, Albert M. Morrishow, George D. Prell

Publikováno v: Journal of Neurochemistry. 68:142-151

In brain, the precursor of imidazoleacetic acid (IAA), a GABAA agonist but a GABAC antagonist, is not known. In the periphery, IAA derives from oxidation of histamine. But in brain, histamine is thought to be metabolized solely by histamine methyltra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6e90c765b9428aa0c77743327aca3e
https://doi.org/10.1046/j.1471-4159.1997.68010142.x

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[Untitled]

Autor: D. Prell, T. Heib, M. Bergé-Hasmann, K.H. Altemeyer, M. Albrech, D. Sinclair

Publikováno v: Notfall & Rettungsmedizin. 4:130-139

In einer retrospektiven Studie wurden die vom Team des Rettungshubschraubers (RTH) Christoph 16 in Saarbrucken in den Jahren 1994–1996 primar versorgten 51 Patienten in einem Glasgow-Coma- Scale (GCS) ≤8 mit Schadelhirntrauma (SHT) und 96 Patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6564a97ed8d2d2d6627e7731a0b0bdb9
https://doi.org/10.1007/s100490170083

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Characterization of Histaminergic H3 Receptors in Intraocular Tuberomammillary Transplants Containing Histaminergic Neurons

Autor: Carl R. Lupica, Ann-Charlotte Granholm, Hanna Bergman, George D. Prell

Publikováno v: Experimental Neurology. 136:12-21

This study was performed to investigate the physicological properties of histaminergic neurons in intraocular hypothalamic transplants. Pieces of posterolateral hypothalamus containing the tuberomammillary nucleus were dissected from Embryonic Day 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1461798e1fd08f0b8a99159ed3cc6879
https://doi.org/10.1006/exnr.1995.1079

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Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: their relationships to levels of other aminergic transmitters and ratings of symptoms

Autor: Charles A. Kaufmann, Markku Linnoila, Jack Peter Green, Darrell G. Kirch, George D. Prell, Albert M. Morrishow, Richard Jed Wyatt, Jai K. Khandelwal

Publikováno v: Schizophrenia Research. 14:93-104

Levels of the histamine metabolites, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), and metabolites of other aminergic transmitters and of norepinephrine were measured in cerebrospinal fluid of 36 inpatients with chronic sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb4fa1e13f0404f4de145af3f596638
https://doi.org/10.1016/0920-9964(94)00034-6

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Accelerating ring artifact correction for flat-detector CT using the CUDA framework

Autor: Willi A. Kalender, D. Prell, Kyriakou Y, W. Chen

Publikováno v: SPIE Proceedings.

Ring artifacts often appear in flat-detector CT because of imperfect or defect detector elements or calibration. In high-spatial resolution CT images reducing such artifacts becomes a necessity. In this paper, we used the post-processing ring correct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d08e16bcdc85f9647b77946a14623fc
https://doi.org/10.1117/12.844254

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The experience of Wernicke's aphasia

Autor: John Pile-Spellman, Ronald M. Lazar, George D. Prell, Randolph S. Marshall

Publikováno v: Neurology. 55:1222-1224

The authors induced a transient Wernicke's aphasia in a patient with left frontal arteriovenous malformation by superselective Wada injection exclusively into the lower division of the left middle cerebral artery. The patient was then asked to recall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf573df9944eaa81c2bb74f0a8d591e3
https://doi.org/10.1212/wnl.55.8.1222

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