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Current Immunotherapeutic Strategies in Pancreatic Cancer

Autor: Janet M. D. Plate

Publikováno v: Surgical Oncology Clinics of North America. 16:919-943

The immune systems of patients with newly diagnosed pancreatic cancers are functional, with T-cell responses capable of responding to tumor antigen presentation. Pancreatic tumors have been demonstrated to express tumor antigens as mutated, altered,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26622ad1c4fe7bf071d869cb2c32ed47
https://doi.org/10.1016/j.soc.2007.07.012

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Clinicopathological Significance of Major Histocompatibility Complex Class I-Related Chain A and B Expression in Thyroid Cancer

Autor: Janet M. D. Plate, Thomas Spies, Xiulong Xu, Michael J. Gaffud, Hans G. Klingemann, Paolo Gattuso, Guitta Maki, Sophie Caillat-Zucman, Veronika Groh, Helen G. Ding, Richard A. Prinz, Geetha Rao

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 91:2704-2712

Major histocompatibility complex class I-related chains A and B (MICA/B) are two stress-inducible ligands for the immunoreceptor NKG2D that is expressed on cytotoxic T cells and natural killer (NK) cells. It is not known whether MICA/B expression is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8df76c26ac374bc75078a521344dabe
https://doi.org/10.1210/jc.2006-0492

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A beamline for high-pressure studies at the Advanced Light Source with a superconducting bending magnet as the source

Autor: D. Plate, A. Paul Alivisatos, Wendel A. Caldwell, Arianna E. Gleason, Raymond Jeanloz, Alastair A. MacDowell, Daniella Cambie, Nicholas Kelez, Howard A. Padmore, Martin Kunz, Simon M. Clark, Robert Duarte, Edward E. Domning, Tony Yu, Richard Celestre, James Glossinger, Joeseph M. Zaug

Publikováno v: Journal of Synchrotron Radiation. 12:650-658

A new facility for high-pressure diffraction and spectroscopy using diamond anvil high-pressure cells has been built at the Advanced Light Source on Beamline 12.2.2. This beamline benefits from the hard X-radiation generated by a 6 Tesla superconduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3406f64637197afd5039953727e2b3
https://doi.org/10.1107/s0909049505020959

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Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas

Autor: Jules E. Harris, Janet M. D. Plate, Susan Bograd, Aileen E. Plate, Susan Shott

Publikováno v: Cancer Immunology, Immunotherapy. 54:915-925

Effects of gemcitabine (Gemzar) on immune cells were examined in pancreas cancer patients to determine whether it was immunosuppressive, or potentially could be combined with vaccines or other immunotherapy to enhance patient's responses to their tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60facb5380b2108a7a30428f977a7ed4
https://doi.org/10.1007/s00262-004-0638-1

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Increased expression of the putative axon growth-repulsive extracellular matrix molecule, keratan sulphate proteoglycan, following traumatic injury of the adult rat spinal cord

Autor: Johannes Noth, A. B. Schmitt, D. Plate, Gary A. Brook, Didier Martin, Jean Schoenen, Félix Scholtes, M. Krautstrunk, W. Nacimiento

Publikováno v: Acta Neuropathologica. 104:592-600

Keratan sulphate proteoglycan (KSPG) is a developmentally regulated barrier molecule, directing axonal growth during central nervous system (CNS) formation. The possible re-expression and functional significance of KSPG in preventing axon regeneratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a830f12964cb7933753f609c35f553b1
https://doi.org/10.1007/s00401-002-0589-6

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Gene expression in chronic lymphocytic leukemia B cells and changes during induction of apoptosis

Autor: Kathryn S Petersen, Janet M. D. Plate, Lela Buckingham, Homayoun Shahidi, Claude M Schofield

Publikováno v: Experimental Hematology. 28:1214-1224

Our studies in chronic lymphocytic leukemia (CLL) are directed at understanding which signals maintain viability in vivo and become lost upon removal of leukemic cells from the body, such that they immediately begin to undergo apoptosis ex vivo. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf28398f3b4c5dba675efd14c1ab2f91
https://doi.org/10.1016/s0301-472x(00)00536-1

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Design of a higher harmonic RF system for the Advanced Light Source

Autor: C. C. Lo, Kenneth Baptiste, John M. Byrd, S. Kosta, M. Franks, D. Plate, R.A. Rimmer, S. De Santis

Publikováno v: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 439:15-25

We report on the design and fabrication of a third harmonic radiofrequency (RF) system for the Advanced Light Source (ALS) to be used for lengthening the bunch and increasing the Touschek-dominated beam lifetime. We plan to install five single-cell 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fcbb44aa32e406bc3bfea217cd1f307
https://doi.org/10.1016/s0168-9002(99)00892-x

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