Zobrazeno 1 - 10
of 634
pro vyhledávání: '"D. Pascoe"'
Autor:
Chinonye Doris Onuzulu, Samantha Lee, Sujata Basu, Jeannette Comte, Yan Hai, Nikho Hizon, Shivam Chadha, Maria Shenna Fauni, Andrew J. Halayko, Christopher D. Pascoe, Meaghan J. Jones
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Smoking is a potent cause of asthma exacerbations, chronic obstructive pulmonary disease (COPD) and many other health defects, and changes in DNA methylation (DNAm) have been identified as a potential link between smoking and these health outcomes. H
Externí odkaz:
https://doaj.org/article/43f8a707b578469baa2af0d1c31ed132
Autor:
Jignesh Vaghasiya, Aruni Jha, Sujata Basu, Alaina Bagan, Siwon K. Jengsuksavat, Amir Ravandi, Christopher D. Pascoe, Andrew J. Halayko
Publikováno v:
Biology, Vol 13, Iss 8, p 627 (2024)
Oxidative stress is associated with asthma pathobiology. We reported that oxidized phosphatidylcholines (OxPCs) are mediators of oxidative stress and accumulate in the lung in response to allergen challenge. The current study begins to unravel mechan
Externí odkaz:
https://doaj.org/article/026b672d2edd4b98a07e6a0b92ca4df0
Autor:
Dina H. D. Mostafa, Mahadevappa Hemshekhar, Hadeesha Piyadasa, Anthony Altieri, Andrew J. Halayko, Christopher D. Pascoe, Neeloffer Mookherjee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Biological sex impacts disease prevalence, severity and response to therapy in asthma, however preclinical studies often use only one sex in murine models. Here, we detail sex-related differences in immune responses using a house dust mite (
Externí odkaz:
https://doaj.org/article/6fbde9b5718e4a2594419abc7621e585
Autor:
Thomas H. Mahood, Christopher D. Pascoe, Tobias K. Karakach, Aruni Jha, Sujata Basu, Peyman Ezzati, Victor Spicer, Neeloffer Mookherjee, Andrew J. Halayko
Publikováno v:
ACS Omega, Vol 6, Iss 2, Pp 1171-1189 (2021)
Externí odkaz:
https://doaj.org/article/74375d0e46a440cb93c0276699ab6f97
Autor:
Danielle D. Wadsworth, Kameron B. Suire, Ashley Peart, Shelby Foote, Chloe Jones, Mynor Rodriguez-Hernandez, James R. McDonald, David D. Pascoe
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 7, Iss 4, p 110 (2022)
The purpose of this project was to examine the effect of a concurrent exercise program (sprint interval training and resistance exercise) on body composition in women with obesity and factors associated with continued exercise participation following
Externí odkaz:
https://doaj.org/article/63ea516d25c6490782c75ed3a4b9a335
Autor:
Jennifer M. Zerbato, Georges Khoury, Wei Zhao, Matthew J. Gartner, Rachel D. Pascoe, Ajantha Rhodes, Ashanti Dantanarayana, Megan Gooey, Jenny Anderson, Peter Bacchetti, Steven G. Deeks, James McMahon, Michael Roche, Thomas A. Rasmussen, Damian FJ Purcell, Sharon R. Lewin
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103241- (2021)
Background: One strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy (ART) is to activate latent HIV infection with a latency reversing agent (LRA). Surrogate markers that acc
Externí odkaz:
https://doaj.org/article/d906ec4beead49649c5521b1bb6e22dd
Publikováno v:
Viruses, Vol 14, Iss 5, p 1108 (2022)
Three early-career female virologists sat down with a distinguished Nobel laureate to discuss two pandemics, 39 years apart [...]
Externí odkaz:
https://doaj.org/article/f2e312901f3148018ba1d7a640bc2de9
Autor:
Renée M Van der Sluis, Jennifer M Zerbato, Jake W Rhodes, Rachel D Pascoe, Ajantha Solomon, Nitasha A Kumar, Ashanti I Dantanarayana, Surekha Tennakoon, Jérémy Dufloo, James McMahon, Judy J Chang, Vanessa A Evans, Paul J Hertzog, Martin R Jakobsen, Andrew N Harman, Sharon R Lewin, Paul U Cameron
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008151 (2020)
HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells d
Externí odkaz:
https://doaj.org/article/d333a0dcff84455782c17a524a0f5301
Autor:
Christopher D. Pascoe, Ma’en Obeidat, Bryna A. Arsenault, Yunlong Nie, Stephanie Warner, Dorota Stefanowicz, Samuel J. Wadsworth, Jeremy A. Hirota, S. Jasemine Yang, Delbert R. Dorscheid, Chris Carlsten, Tillie L. Hackett, Chun Y. Seow, Peter D. Paré
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial bar
Externí odkaz:
https://doaj.org/article/e66410ac5d12451d8dc6921708813749
Autor:
Danielle D, Wadsworth, Mynor, Rodriguez-Hernandez, Lorena S, Huffman, James R, McDonald, Katherine E, Spring, David D, Pascoe
Publikováno v:
Journal of Strength and Conditioning Research. 36:3217-3223
Wadsworth, DD, Rodriguez-Hernandez, M, Huffman, LS, McDonald, JR, Spring, KE, and Pascoe, DD. Adaptations to a concurrent exercise training program in inactive aging women. J Strength Cond Res 36(11): 3217-3223, 2022-This study assessed the effect of